Marco Gobbi Selected Research

Doxycycline (Periostat)

10/2021	Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice.
1/2021	Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity.
9/2019	The Anti-Amyloidogenic Action of Doxycycline: A Molecular Dynamics Study on the Interaction with Aβ42.
1/2019	Plasma and Brain Concentrations of Doxycycline after Single and Repeated Doses in Wild-Type and APP23 Mice.
10/2018	Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models.
2/2014	Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.
9/2013	Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.
6/2012	Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study.

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Marco Gobbi Research Topics

Disease

21	Neoplasms (Cancer) 10/2022 - 04/2002
20	Alzheimer Disease (Alzheimer's Disease) 09/2019 - 03/2009
12	Multiple Myeloma 02/2024 - 02/2002
11	Leukemia 11/2023 - 01/2003
11	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2019 - 01/2006
10	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 11/2004
10	Lymphoma (Lymphomas) 01/2022 - 03/2007
8	Prion Diseases (Transmissible Spongiform Encephalopathies) 10/2021 - 01/2006
7	Infections 07/2023 - 02/2003
7	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 10/2019 - 02/2003
7	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019 - 02/2004
6	Hodgkin Disease (Hodgkin's Disease) 01/2022 - 10/2005
5	Heart Arrest (Cardiac Arrest) 11/2023 - 08/2014
5	Hematologic Neoplasms (Hematological Malignancy) 10/2020 - 06/2009
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2014 - 10/2005
4	Brain Injuries (Brain Injury) 11/2023 - 09/2012
4	Amyloidosis 11/2022 - 09/2013
4	COVID-19 02/2022 - 01/2021
4	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2013 - 10/2003
3	Breast Neoplasms (Breast Cancer) 10/2022 - 07/2012
3	Residual Neoplasm 11/2021 - 11/2012
3	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 02/2014 - 01/2006
3	Disease Progression 01/2013 - 04/2002
3	Anemia 11/2011 - 02/2004
3	Seizures (Absence Seizure) 06/2008 - 02/2005
2	Neutropenia 12/2023 - 01/2008
2	Fatal Familial Insomnia 10/2021 - 09/2013
2	Reperfusion Injury 01/2021 - 03/2016
2	Polyneuropathies (Polyneuropathy) 01/2021 - 06/2007
2	Brain Ischemia (Cerebral Ischemia) 01/2021 - 09/2012
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020 - 01/2014
2	Neuroinflammatory Diseases 01/2019 - 10/2018
2	Gliosis 01/2019 - 03/2017
2	Hairy Cell Leukemia 01/2018 - 11/2009
2	Genomic Instability 03/2016 - 01/2015
2	Cognitive Dysfunction 10/2014 - 02/2010
2	Inflammation (Inflammations) 08/2014 - 04/2010

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 02/2024 - 04/2002
14	Amyloid (Amyloid Fibrils)IBA 10/2018 - 01/2006
12	Peptides (Polypeptides)IBA 07/2023 - 04/2010
10	Cytarabine (Cytosar-U)FDA LinkGeneric 12/2023 - 11/2004
10	fludarabineIBA 01/2019 - 02/2003
8	Doxycycline (Periostat)FDA LinkGeneric 10/2021 - 06/2012
8	Rituximab (Mabthera)FDA Link 01/2020 - 07/2004
6	Prion ProteinsIBA 10/2021 - 01/2006
6	NAD (NADH)IBA 01/2018 - 01/2011
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2010
5	CytokinesIBA 01/2014 - 07/2004
5	Imatinib Mesylate (Gleevec)FDA Link 04/2011 - 01/2006
4	KynurenineIBA 11/2023 - 08/2014
4	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2021 - 09/2012
4	Dexamethasone (Maxidex)FDA LinkGeneric 12/2020 - 01/2018
4	Bortezomib (Velcade)FDA Link 12/2020 - 08/2013
4	Tyrosine Kinase InhibitorsIBA 10/2020 - 10/2015
4	Bendamustine Hydrochloride FDA Link 10/2019 - 09/2011
4	AntibodiesIBA 01/2019 - 06/2007
4	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2018 - 11/2004
4	LigandsIBA 03/2017 - 08/2011
4	Etoposide (VP 16)FDA LinkGeneric 11/2014 - 10/2005
4	Erythropoietin FDA Link 06/2013 - 02/2004
4	Amyloid beta-PeptidesIBA 07/2012 - 03/2009
3	Azacitidine (5 Azacytidine)FDA Link 12/2023 - 08/2009
3	EnzymesIBA 11/2023 - 10/2012
3	Neuroprotective AgentsIBA 11/2023 - 12/2020
3	Antiviral Agents (Antivirals)IBA 02/2022 - 01/2021
3	Complement System Proteins (Complement)IBA 01/2020 - 07/2011
3	PrionsIBA 01/2019 - 02/2014
3	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2019 - 11/2008
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2018 - 10/2007
3	nilotinib FDA Link 01/2018 - 02/2008
3	Nicotinamide PhosphoribosyltransferaseIBA 12/2016 - 08/2013
3	Melphalan (Alkeran)FDA LinkGeneric 11/2014 - 10/2005
3	Valproic Acid (Depakote)FDA LinkGeneric 02/2012 - 08/2009
3	Mitoxantrone (Novantrone)FDA LinkGeneric 04/2008 - 07/2004
2	ursodoxicoltaurineIBA 02/2024 - 06/2012
2	Oxidoreductases (Dehydrogenase)IBA 02/2024 - 01/2021
2	Liposomes (Liposome)IBA 12/2023 - 08/2011
2	Glucose (Dextrose)FDA LinkGeneric 11/2023 - 01/2022
2	Tryptophan (L-Tryptophan)FDA Link 11/2023 - 08/2014
2	SugarsIBA 11/2023 - 04/2011
2	VaccinesIBA 01/2022 - 05/2020
2	Infliximab (Remicade)FDA Link 01/2021 - 01/2019
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 04/2002
2	Thalidomide (Thalomid)FDA Link 12/2020 - 04/2002
2	ibrutinibIBA 10/2020 - 12/2016
2	Phosphotransferases (Kinase)IBA 10/2020 - 02/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2015
2	Protein Isoforms (Isoforms)IBA 01/2017 - 03/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 03/2016 - 01/2011
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 09/2015 - 10/2014
2	N- (4- (1- benzoylpiperidin- 4- yl)butyl)- 3- (pyridin- 3- yl)acrylamideIBA 09/2015 - 06/2009
2	Ranolazine FDA Link 10/2014 - 09/2014

Therapy/Procedure

30	Therapeutics 11/2023 - 04/2002
6	Drug Therapy (Chemotherapy) 12/2018 - 02/2002
5	Stem Cell Transplantation 11/2021 - 04/2002
4	Transplantation 01/2020 - 01/2008
3	Salvage Therapy 10/2005 - 04/2002
2	Induction Chemotherapy 12/2023 - 11/2008
2	Cardiopulmonary Resuscitation (CPR) 12/2020 - 09/2014
2	Retreatment 01/2020 - 01/2018