Akihiko Gemma Selected Research

Idiopathic Interstitial Pneumonias

1/2024	Identification of kynurenine and quinolinic acid as promising serum biomarkers for drug-induced interstitial lung diseases.
9/2023	Carboplatin and weekly paclitaxel in combination with bevacizumab for the treatment of advanced non-small cell lung cancer complicated by idiopathic interstitial pneumonias: A feasibility study.
11/2022	Identification and characterization of lysophosphatidylcholine 14:0 as a biomarker for drug-induced lung disease.
4/2020	Acute exacerbation of idiopathic interstitial pneumonias related to chemotherapy for lung cancer: nationwide surveillance in Japan.
12/2019	Weekly paclitaxel in combination with carboplatin for advanced non-small-cell lung cancer complicated by idiopathic interstitial pneumonias: a single-arm phase II study.
4/2011	The feasibility study of Carboplatin plus Etoposide for advanced small cell lung cancer with idiopathic interstitial pneumonias.
1/2011	The safety and efficacy of weekly paclitaxel in combination with carboplatin for advanced non-small cell lung cancer with idiopathic interstitial pneumonias.
1/2009	Exacerbation of idiopathic interstitial pneumonias associated with lung cancer therapy.

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Akihiko Gemma Research Topics

Disease

83	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2023 - 06/2003
62	Lung Neoplasms (Lung Cancer) 09/2023 - 06/2003
50	Neoplasms (Cancer) 01/2024 - 06/2003
34	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2024 - 08/2003
17	Chronic Obstructive Pulmonary Disease (COPD) 02/2024 - 01/2011
15	Adenocarcinoma 01/2020 - 06/2003
14	Disease Progression 02/2024 - 12/2009
14	Adenocarcinoma of Lung 04/2022 - 02/2007
14	Idiopathic Pulmonary Fibrosis 09/2021 - 04/2009
11	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022 - 06/2003
9	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 01/2012
9	Pneumonia (Pneumonitis) 12/2019 - 03/2010
8	Idiopathic Interstitial Pneumonias 01/2024 - 01/2009
8	Dyspnea (Shortness of Breath) 01/2023 - 10/2011
7	Lung Diseases (Lung Disease) 01/2024 - 02/2014
7	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2003
7	Renal Cell Carcinoma (Grawitz Tumor) 08/2020 - 01/2013
7	Emphysema 01/2018 - 02/2012
6	Respiratory Insufficiency (Respiratory Failure) 02/2024 - 07/2012
6	Lung Injury 01/2024 - 07/2008
6	Pleural Effusion (Pleural Effusions) 09/2022 - 04/2011
6	Neutropenia 12/2021 - 06/2008
6	Carcinogenesis 01/2021 - 08/2003
6	Drug-Related Side Effects and Adverse Reactions 08/2020 - 07/2011
5	Inflammation (Inflammations) 01/2024 - 08/2012
5	Fever (Fevers) 11/2022 - 06/2008
5	Fibrosis (Cirrhosis) 01/2021 - 06/2015
5	Malignant Mesothelioma 02/2019 - 06/2008
4	Pulmonary Hypertension 02/2024 - 01/2015
4	Brain Neoplasms (Brain Tumor) 01/2020 - 04/2016
4	Nausea 01/2019 - 04/2014
4	Infections 05/2018 - 03/2010
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2016 - 07/2005
4	Colorectal Neoplasms (Colorectal Cancer) 12/2015 - 08/2003
3	Granuloma 01/2023 - 01/2013
3	Vomiting 04/2022 - 01/2016
3	Organizing Pneumonia 01/2022 - 01/2019
3	Leukopenia 12/2021 - 11/2006
3	Febrile Neutropenia 12/2021 - 04/2014
3	Mesothelioma 01/2021 - 06/2008
3	Breast Neoplasms (Breast Cancer) 01/2020 - 06/2010
3	Malignant Pleural Effusion 01/2020 - 04/2011
3	Diarrhea 08/2019 - 05/2013
3	Pulmonary Edema 01/2019 - 01/2014

Drug/Important Bio-Agent (IBA)

28	ErbB Receptors (EGF Receptor)IBA 04/2022 - 08/2003
26	Carboplatin (JM8)FDA LinkGeneric 09/2023 - 06/2006
24	Tyrosine Kinase InhibitorsIBA 04/2021 - 02/2007
22	Proteins (Proteins, Gene)FDA Link 03/2021 - 08/2003
22	Gefitinib (Iressa)FDA Link 01/2021 - 08/2003
18	Biomarkers (Surrogate Marker)IBA 01/2024 - 12/2006
17	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 04/2004
16	Paclitaxel (Taxol)FDA LinkGeneric 09/2023 - 06/2006
14	Docetaxel (Taxotere)FDA Link 06/2023 - 06/2006
10	Bevacizumab (Avastin)FDA Link 09/2023 - 02/2013
9	osimertinibIBA 02/2022 - 01/2018
8	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2023 - 07/2016
8	MicroRNAs (MicroRNA)IBA 03/2023 - 07/2009
8	pembrolizumabIBA 11/2022 - 01/2018
7	B7-H1 AntigenIBA 06/2023 - 01/2018
7	Pemetrexed (MTA)FDA Link 02/2022 - 06/2008
7	AfatinibIBA 04/2021 - 10/2018
7	Anaplastic Lymphoma KinaseIBA 03/2021 - 05/2013
7	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021 - 04/2011
7	Irinotecan (Camptosar)FDA LinkGeneric 05/2013 - 04/2004
6	130-nm albumin-bound paclitaxelIBA 06/2023 - 08/2017
6	Gemcitabine FDA Link 01/2018 - 06/2006
5	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2024 - 02/2012
5	LigandsIBA 03/2023 - 12/2006
5	Immune Checkpoint InhibitorsIBA 03/2023 - 01/2020
5	NivolumabIBA 11/2021 - 07/2017
5	CrizotinibIBA 07/2019 - 04/2015
5	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2019 - 11/2012
5	DNA (Deoxyribonucleic Acid)IBA 08/2012 - 11/2003
4	Bosentan (Tracleer)FDA Link 02/2024 - 01/2015
4	Antineoplastic Agents (Antineoplastics)IBA 01/2024 - 10/2007
4	SteroidsIBA 01/2022 - 02/2009
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021 - 01/2012
4	Monoclonal AntibodiesIBA 01/2019 - 08/2015
4	Vinorelbine (Navelbine)FDA LinkGeneric 01/2018 - 06/2006
4	Etoposide (VP 16)FDA LinkGeneric 10/2012 - 12/2007
4	Histone Deacetylase InhibitorsIBA 06/2010 - 11/2007
4	Complementary DNA (cDNA)IBA 01/2009 - 06/2003
3	TOR Serine-Threonine KinasesIBA 01/2024 - 04/2015
3	Everolimus FDA Link 01/2024 - 01/2013
3	AntibodiesIBA 06/2023 - 01/2020
3	nintedanibIBA 01/2023 - 06/2015
3	CytokinesIBA 08/2022 - 08/2007
3	Albumin-Bound Paclitaxel FDA Link 04/2022 - 02/2019
3	Carbon MonoxideIBA 09/2021 - 01/2013
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 03/2021 - 05/2012
3	AsbestosIBA 01/2021 - 05/2015
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 02/2013
3	RNA (Ribonucleic Acid)IBA 01/2020 - 11/2003
3	PlatinumIBA 05/2019 - 07/2015

Therapy/Procedure

56	Therapeutics 02/2024 - 06/2003
41	Drug Therapy (Chemotherapy) 09/2023 - 08/2003
7	Aftercare (After-Treatment) 09/2022 - 12/2009
5	Combination Drug Therapy (Combination Chemotherapy) 04/2020 - 12/2007
4	Activities of Daily Living (ADL) 02/2024 - 10/2011
4	Radiotherapy 01/2019 - 04/2011