Richard D Gelber Selected Research

Letrozole (Femara)

2/2021	Cumulative incidence of cardiovascular events under tamoxifen and letrozole alone and in sequence: a report from the BIG 1-98 trial.
3/2020	Correction: Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
10/2019	Neoadjuvant Degarelix Versus Triptorelin in Premenopausal Patients Who Receive Letrozole for Locally Advanced Endocrine-Responsive Breast Cancer: A Randomized Phase II Trial.
10/2019	Adjuvant Letrozole and Tamoxifen Alone or Sequentially for Postmenopausal Women With Hormone Receptor-Positive Breast Cancer: Long-Term Follow-Up of the BIG 1-98 Trial.
1/2019	Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial.
1/2018	Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial.
4/2016	Identifying treatment effect heterogeneity in clinical trials using subpopulations of events: STEPP.
1/2016	Treatment Adherence and Its Impact on Disease-Free Survival in the Breast International Group 1-98 Trial of Tamoxifen and Letrozole, Alone and in Sequence.
12/2015	ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer.
9/2015	Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.

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Richard D Gelber Research Topics

Disease

142	Breast Neoplasms (Breast Cancer) 02/2024 - 03/2003
57	Neoplasms (Cancer) 01/2024 - 04/2002
6	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 02/2007 - 03/2002
4	Cardiotoxicity 02/2022 - 03/2002
4	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 12/2005
4	Heart Failure 01/2020 - 12/2002
4	Amenorrhea 01/2019 - 03/2006
4	Hypercholesterolemia 04/2017 - 12/2005
3	Pathologic Complete Response 11/2022 - 04/2016
3	Arthralgia (Joint Pain) 01/2018 - 02/2007
3	Hot Flashes 11/2016 - 01/2007
3	Acquired Immunodeficiency Syndrome (AIDS) 06/2007 - 07/2002
2	Melanoma (Melanoma, Malignant) 02/2023 - 01/2018
2	Left Ventricular Dysfunction 02/2022 - 12/2002
2	Diarrhea 01/2020 - 07/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 01/2018
2	Lung Neoplasms (Lung Cancer) 01/2019 - 04/2002
2	Premature Menopause 01/2019 - 07/2007
2	Hypertension (High Blood Pressure) 01/2018 - 12/2007
2	Triple Negative Breast Neoplasms 01/2016 - 06/2010
2	Lobular Carcinoma 09/2015 - 06/2013
2	Obesity 11/2012 - 01/2010
2	Bone Fractures (Bone Fracture) 04/2008 - 02/2007
2	Uterine Hemorrhage (Uterine Bleeding) 02/2007 - 12/2005
1	Fatigue 02/2024
1	Chronic Disease (Chronic Diseases) 02/2024
1	Myocardial Ischemia (Ischemic Heart Diseases) 02/2021
1	Overweight 10/2020
1	Autoimmune Diseases (Autoimmune Disease) 02/2019
1	Spontaneous Abortion (Miscarriage) 01/2019
1	Leukopenia 10/2016
1	Vaginal Discharge 10/2016
1	Adenoma (Adenomas) 01/2016
1	Polyps 01/2016
1	Ductal Carcinoma 09/2015
1	Erythema 09/2014
1	Exanthema (Rash) 09/2014

Drug/Important Bio-Agent (IBA)

48	Tamoxifen FDA LinkGeneric 06/2023 - 09/2003
43	Hormones (Hormone)IBA 05/2023 - 10/2004
33	Trastuzumab (Herceptin)FDA Link 01/2024 - 10/2005
28	Letrozole (Femara)FDA LinkGeneric 02/2021 - 12/2005
25	Estrogen ReceptorsIBA 01/2020 - 03/2003
14	human ERBB2 proteinIBA 01/2024 - 06/2009
14	Aromatase InhibitorsIBA 06/2023 - 12/2005
13	Progesterone Receptors (Progesterone Receptor)IBA 01/2023 - 03/2003
12	ErbB Receptors (EGF Receptor)IBA 02/2024 - 07/2013
12	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019 - 04/2003
10	exemestane (Aromasin)FDA Link 01/2023 - 07/2014
9	Methotrexate (Mexate)FDA LinkGeneric 10/2016 - 04/2003
8	Lapatinib (GW572016)FDA Link 01/2021 - 02/2012
7	Estrogens (Estrogen)FDA Link 01/2023 - 09/2007
7	Fluorouracil (Carac)FDA LinkGeneric 06/2010 - 04/2003
7	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2010 - 03/2002
6	pertuzumabIBA 01/2024 - 07/2017
6	Biomarkers (Surrogate Marker)IBA 11/2022 - 03/2003
5	Goserelin (Zoladex)FDA Link 01/2019 - 12/2003
5	SteroidsIBA 11/2011 - 10/2004
4	Paclitaxel (Taxol)FDA LinkGeneric 02/2022 - 09/2014
4	Monoclonal AntibodiesIBA 01/2017 - 10/2005
4	Nevirapine (Viramune)FDA Link 06/2007 - 07/2002
3	Immune Checkpoint InhibitorsIBA 01/2024 - 01/2018
3	Phenobarbital (Luminal)FDA Link 01/2024 - 10/2019
3	Epidermal Growth Factor (EGF)IBA 01/2023 - 02/2014
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 10/2019 - 12/2003
3	DNA (Deoxyribonucleic Acid)IBA 12/2015 - 06/2010
3	Progesterone FDA LinkGeneric 04/2013 - 09/2007
3	AnthracyclinesIBA 08/2010 - 01/2006
2	olaparibIBA 02/2024 - 01/2021
2	Ado-Trastuzumab EmtansineIBA 02/2022 - 01/2021
2	Estrogen Receptor alphaIBA 11/2016 - 12/2015
2	Proteins (Proteins, Gene)FDA Link 11/2012 - 04/2003
2	Docetaxel (Taxotere)FDA Link 01/2010 - 01/2008
2	Epirubicin (Ellence)FDA LinkGeneric 01/2009 - 01/2006
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2023
1	Poly Adenosine Diphosphate RiboseIBA 01/2021
1	AntidiarrhealsIBA 01/2020
1	antineoplaston A10 (A 10)IBA 01/2020
1	taxaneIBA 01/2020
1	Triptorelin Pamoate (Trelstar)FDA Link 10/2019
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 10/2019
1	Cyclin D1IBA 01/2018
1	CholesterolIBA 04/2017
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2016
1	Transaminases (Aminotransferases)IBA 10/2016
1	Hematoxylin (Haematoxylon)IBA 01/2016
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2016
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2016

Therapy/Procedure

86	Therapeutics 02/2024 - 07/2002
54	Drug Therapy (Chemotherapy) 01/2024 - 04/2002
24	Adjuvant Chemotherapy 02/2024 - 04/2003
9	Radiotherapy 02/2024 - 07/2004
4	Neoadjuvant Therapy 11/2022 - 02/2008
4	Immunotherapy 11/2022 - 01/2018
3	Mastectomy (Mammectomy) 01/2018 - 06/2008
3	Segmental Mastectomy (Lumpectomy) 10/2016 - 06/2008
1	Induced Abortion (Induced Abortions) 01/2019
1	Aftercare (After-Treatment) 01/2019
1	Chemoprevention 01/2016
1	Maintenance Chemotherapy 01/2016