Amalia Gastaldelli Selected Research

Insulin (Novolin)

5/2024	Clusters of adipose tissue dysfunction in adults with type 2 diabetes identify those with worse lipidomic profile despite similar glycaemic control.
4/2024	Baseline phenotypes with preserved β-cell function and high insulin concentrations have the best improvements in glucose tolerance after weight loss: results from the prospective DEXLIFE and EGIR-RISC studies.
12/2023	Reduced Insulin Clearance Differently Relates to Increased Liver Lipid Content and Worse Glycemic Control in Recent-Onset Type 2 and Type 1 Diabetes.
10/2023	Insulin Clearance in Health and Disease.
10/2023	Bariatric Surgery Alters the Postprandial Recovery From Hypoglycemia, Mediated by Cholinergic Signal.
9/2023	Contribution of endogenous glucagon-like peptide 1 to prandial counterregulatory responses to hypoglycemia after bariatric surgery.
7/2023	Emergence of a New Gluco-Regulatory Mechanism for Glycemic Control with Dapagliflozin/Exenatide Therapy in Type 2 Diabetes.
4/2023	Role of Insulin Clearance in Insulin Action and Metabolic Diseases.
3/2023	Insulinotropic effect of endogenous incretins is greater after gastric bypass than sleeve gastrectomy despite diminished beta-cell sensitivity to plasma incretins.
1/2023	Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes.

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Amalia Gastaldelli Research Topics

Disease

122	Insulin Resistance 05/2024 - 11/2002
71	Type 2 Diabetes Mellitus (MODY) 05/2024 - 11/2002
50	Non-alcoholic Fatty Liver Disease 08/2023 - 06/2005
27	Obesity 05/2024 - 12/2004
21	Fibrosis (Cirrhosis) 08/2023 - 06/2005
21	Hyperglycemia 03/2023 - 02/2002
19	Glucose Intolerance 01/2021 - 01/2005
16	Inflammation (Inflammations) 01/2022 - 11/2006
13	Weight Loss (Weight Reduction) 04/2024 - 12/2004
13	Fatty Liver 03/2022 - 05/2012
12	Body Weight (Weight, Body) 01/2022 - 08/2006
11	Hyperinsulinism (Hyperinsulinemia) 11/2023 - 05/2006
11	Liver Diseases (Liver Disease) 01/2021 - 06/2005
10	Hypoglycemia (Reactive Hypoglycemia) 02/2024 - 03/2014
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 11/2006
7	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2018 - 06/2005
5	Overweight 05/2024 - 04/2009
5	Hypertension (High Blood Pressure) 01/2021 - 02/2008
4	Alcoholic Fatty Liver 08/2023 - 10/2007
3	Metabolic Diseases (Metabolic Disease) 04/2023 - 09/2020
3	Atherosclerosis 02/2022 - 01/2009
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 06/2011
3	Weight Gain 11/2021 - 10/2007
3	Morbid Obesity 01/2021 - 01/2020
3	Neoplasms (Cancer) 01/2017 - 06/2011
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2023 - 01/2022
2	Dysbiosis 01/2021 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 11/2017
2	Infections 12/2019 - 11/2018
2	Necrosis 01/2017 - 11/2006

Drug/Important Bio-Agent (IBA)

110	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 11/2002
88	Insulin (Novolin)FDA Link 05/2024 - 02/2002
25	LipidsIBA 05/2024 - 10/2003
15	Pioglitazone (Actos)FDA Link 01/2023 - 08/2006
15	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
13	Glucagon-Like Peptide 1 (GLP 1)IBA 02/2024 - 10/2011
12	Nonesterified Fatty Acids (NEFA)IBA 11/2022 - 10/2003
12	Triglycerides (Triacylglycerol)IBA 11/2022 - 06/2005
11	Hormones (Hormone)IBA 02/2024 - 08/2006
11	Glucagon (Glukagon)FDA Link 10/2023 - 08/2009
10	AdiponectinIBA 11/2022 - 06/2005
9	EnzymesIBA 01/2023 - 01/2009
9	C-PeptideIBA 10/2019 - 12/2002
8	Metformin (Glucophage)FDA LinkGeneric 05/2024 - 06/2004
8	Exenatide (Byetta)FDA Link 07/2023 - 04/2014
8	Glycerol (Glycerine)FDA LinkGeneric 12/2020 - 09/2009
7	Fatty Acids (Saturated Fatty Acids)IBA 05/2024 - 01/2011
7	IncretinsIBA 11/2023 - 12/2002
6	Alanine Transaminase (SGPT)IBA 01/2022 - 11/2006
6	ThiazolidinedionesIBA 01/2021 - 03/2006
5	Sodium-Glucose Transporter 2 InhibitorsIBA 12/2023 - 01/2020
5	Glucagon-Like Peptide-1 ReceptorIBA 09/2023 - 10/2011
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 11/2006
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2006
4	Diethylhexyl Phthalate (DEHP)IBA 11/2023 - 09/2018
4	Amino Acids FDA Link 08/2023 - 01/2018
4	dapagliflozinIBA 07/2023 - 01/2020
4	Protons (Proton)IBA 01/2022 - 07/2011
4	Hemoglobins (Hemoglobin)IBA 01/2021 - 08/2006
4	Messenger RNA (mRNA)IBA 02/2020 - 04/2012
3	Sitagliptin Phosphate (Januvia)FDA Link 03/2023 - 08/2012
3	AdipokinesIBA 11/2022 - 05/2012
3	Serine (L-Serine)FDA Link 03/2022 - 01/2016
3	CeramidesIBA 03/2022 - 01/2018
3	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 01/2022 - 11/2006
3	Advanced Glycation End ProductsIBA 01/2022 - 11/2006
3	Peptides (Polypeptides)IBA 01/2022 - 07/2009
3	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2021 - 05/2012
3	C-Reactive ProteinIBA 01/2021 - 11/2006
3	mastihaIBA 01/2021 - 01/2021
3	LeptinIBA 12/2019 - 01/2018
3	LigandsIBA 08/2019 - 11/2006
3	Rosiglitazone (Avandia)FDA Link 11/2006 - 06/2004
2	AcidsIBA 05/2024 - 05/2012
2	Blood Glucose (Blood Sugar)IBA 02/2024 - 04/2012
2	bisphenol AIBA 11/2023 - 12/2022
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 03/2022 - 01/2018
2	Glutamic Acid (Glutamate)FDA Link 03/2022 - 01/2018
2	Environmental Pollutants (Pollutants, Environmental)IBA 02/2022 - 01/2019
2	IronIBA 01/2022 - 01/2021
2	AcyltransferasesIBA 01/2022 - 02/2020
2	Phospholipases (Phospholipase)IBA 01/2022 - 07/2011
2	SphingolipidsIBA 01/2022 - 01/2021
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2021 - 01/2017
2	DiglyceridesIBA 01/2021 - 12/2019
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 12/2019
2	PhosphoenolpyruvateIBA 01/2021 - 01/2018
2	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 01/2021 - 01/2018
2	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2021
2	Liver GlycogenIBA 12/2020 - 01/2020
2	Phosphatidylinositols (Phosphatidylinositol)IBA 02/2020 - 01/2017
2	GhrelinIBA 10/2018 - 06/2016
2	Insulin ReceptorIBA 01/2017 - 07/2009
2	Insulin Glargine (Lantus)FDA Link 01/2017 - 11/2006

Therapy/Procedure

16	Bariatric Surgery 10/2023 - 12/2004
15	Gastric Bypass (Roux-en-Y Gastric Bypass) 02/2024 - 02/2011
11	Glycemic Control 12/2023 - 11/2002
8	Gastrectomy 11/2023 - 09/2014
8	Therapeutics 07/2023 - 11/2006
3	Liver Transplantation 08/2020 - 06/2011