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Yasuhiro Fujiwara Selected Research

Trastuzumab (Herceptin)

1/2020Cardiac Safety of the Trastuzumab Biosimilar ABP 980 in Women with HER2-Positive Early Breast Cancer in the Randomized, Double-Blind, Active-Controlled LILAC Study.
12/2019Totality of Scientific Evidence in the Development of ABP 980, a Biosimilar to Trastuzumab.
7/2019Comparison of the efficacy of trastuzumab emtansine between patients with metastatic human epidermal growth factor receptor 2-positive breast cancers previously treated with combination trastuzumab and pertuzumab and with trastuzumab only in Japanese population.
1/2019Trastuzumab emtansine plus pertuzumab in Japanese patients with HER2-positive metastatic breast cancer: a phase Ib study.
7/2016Fc-Gamma receptor polymorphism and gene expression of peripheral blood mononuclear cells in patients with HER2-positive metastatic breast cancer receiving single-agent trastuzumab.
1/2015Phase I and pharmacokinetic study of trastuzumab emtansine in Japanese patients with HER2-positive metastatic breast cancer.
1/2015(64)Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients.
11/2013Extended trastuzumab therapy improves the survival of HER2-positive breast cancer patients following surgery and radiotherapy for brain metastases.
8/2013A phase II study of lapatinib for brain metastases in patients with HER2-overexpressing breast cancer following trastuzumab based systemic therapy and cranial radiotherapy: subset analysis of Japanese patients.
2/2012Randomized phase II study of primary systemic chemotherapy and trastuzumab for operable HER2 positive breast cancer.
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Yasuhiro Fujiwara Research Topics

Disease

101Neoplasms (Cancer)
05/2024 - 12/2004
73Breast Neoplasms (Breast Cancer)
06/2023 - 12/2004
29Gastroesophageal Reflux (GERD)
10/2023 - 05/2004
25Neoplasm Metastasis (Metastasis)
04/2021 - 06/2008
23Hemorrhage
04/2024 - 01/2008
23Ulcerative Colitis
11/2023 - 09/2003
22Ulcer
06/2022 - 07/2002
17Pathologic Constriction (Stenosis)
12/2023 - 08/2004
17Infections
02/2022 - 07/2002
16Inflammation (Inflammations)
05/2024 - 01/2004
16Crohn Disease (Crohn's Disease)
06/2023 - 09/2003
14Disease Progression
01/2023 - 02/2005
13Stomach Neoplasms (Stomach Cancer)
04/2021 - 10/2005
12Peptic Esophagitis (Reflux Esophagitis)
01/2022 - 01/2003
10Triple Negative Breast Neoplasms
12/2023 - 04/2012
10COVID-19
11/2023 - 06/2021
10Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2022 - 09/2003
10Carcinoma (Carcinomatosis)
12/2020 - 09/2005
10Stomach Ulcer (Gastric Ulcer)
05/2013 - 07/2002
9Adenocarcinoma
12/2023 - 04/2005
9Esophagitis
01/2022 - 01/2003
8Eosinophilic Esophagitis
06/2023 - 01/2019
7Peptic Ulcer (Peptic Ulcers)
01/2024 - 09/2002
7Brain Neoplasms (Brain Tumor)
09/2022 - 11/2008
7Lung Neoplasms (Lung Cancer)
01/2022 - 09/2004
7Esophageal Neoplasms (Esophageal Cancer)
01/2021 - 12/2008
7Heartburn (Pyrosis)
03/2015 - 01/2005
6Uterine Cervical Neoplasms (Cancer of the Cervix)
05/2024 - 08/2011
6Colorectal Neoplasms (Colorectal Cancer)
01/2023 - 01/2005
6Non-Erosive Reflux Disease
01/2022 - 11/2011
6Diarrhea
01/2021 - 08/2002
6Ovarian Neoplasms (Ovarian Cancer)
12/2020 - 06/2009
6Pathologic Complete Response
12/2019 - 09/2005
6Wounds and Injuries (Trauma)
01/2017 - 10/2004
5Sarcoma (Soft Tissue Sarcoma)
05/2024 - 09/2010
5Fistula
12/2023 - 06/2008
5Pancreatic Neoplasms (Pancreatic Cancer)
12/2022 - 11/2010
5Dysbiosis
05/2022 - 01/2017
5Pain (Aches)
04/2021 - 01/2011
5Rheumatoid Arthritis
01/2017 - 01/2008
5Carcinogenesis
02/2016 - 01/2010
4Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2023 - 01/2003
4Esophageal Stenosis (Esophageal Stricture)
06/2022 - 04/2016
4Sleep Initiation and Maintenance Disorders (Insomnia)
10/2021 - 01/2016
4Endometrial Neoplasms (Endometrial Cancer)
10/2021 - 08/2005
4Colitis
09/2021 - 12/2008

Drug/Important Bio-Agent (IBA)

29Proton Pump InhibitorsIBA
10/2023 - 03/2004
27AcidsIBA
01/2024 - 01/2003
17Biomarkers (Surrogate Marker)IBA
05/2024 - 11/2005
17Trastuzumab (Herceptin)FDA Link
01/2020 - 01/2009
16Proteins (Proteins, Gene)FDA Link
12/2023 - 05/2004
15Messenger RNA (mRNA)IBA
08/2022 - 01/2003
15Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
04/2021 - 08/2002
15Paclitaxel (Taxol)FDA LinkGeneric
10/2019 - 02/2005
14ErbB Receptors (EGF Receptor)IBA
02/2023 - 11/2005
14Hormones (Hormone)IBA
01/2023 - 12/2004
14human ERBB2 proteinIBA
01/2023 - 08/2009
13CytokinesIBA
08/2022 - 01/2003
12Capsules (Microcapsules)IBA
12/2022 - 07/2006
12taxaneIBA
04/2020 - 09/2005
11AnthracyclinesIBA
01/2020 - 09/2005
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2022 - 01/2003
9Cisplatin (Platino)FDA LinkGeneric
12/2021 - 08/2005
9Estrogen ReceptorsIBA
07/2017 - 11/2008
8Monoclonal AntibodiesIBA
04/2021 - 12/2004
8Fluorouracil (Carac)FDA LinkGeneric
01/2021 - 01/2004
8PlatinumIBA
05/2012 - 09/2005
7SteroidsIBA
09/2023 - 03/2008
7AntigensIBA
01/2023 - 01/2003
7Rabeprazole (Aciphex)FDA Link
02/2021 - 01/2003
7Carboplatin (JM8)FDA LinkGeneric
11/2017 - 09/2005
7rebamipideIBA
09/2015 - 07/2002
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2014 - 08/2005
6InflammasomesIBA
06/2022 - 07/2016
6Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
02/2021 - 11/2008
6Infliximab (Remicade)FDA Link
03/2018 - 03/2014
6DenosumabFDA Link
11/2017 - 06/2008
6Progesterone Receptors (Progesterone Receptor)IBA
07/2017 - 10/2007
51- (5- (2- fluorophenyl)- 1- (pyridin- 3- ylsulfonyl)- 1H- pyrrol- 3- yl)- N- methylmethanamineIBA
04/2024 - 01/2017
5DNA (Deoxyribonucleic Acid)IBA
12/2023 - 05/2018
5Epidermal Growth Factor (EGF)IBA
02/2023 - 05/2004
5Doxorubicin (Adriamycin)FDA LinkGeneric
01/2023 - 08/2005
5Acetic Acid (Vinegar)FDA LinkGeneric
06/2022 - 07/2002
5Indomethacin (Indometacin)FDA LinkGeneric
01/2021 - 01/2004
5eribulinFDA Link
06/2020 - 12/2017
5Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
05/2020 - 01/2004
5ProstaglandinsIBA
05/2020 - 02/2010
4Polyglycolic Acid (Polyglycolide)IBA
12/2023 - 09/2016
4Adrenal Cortex Hormones (Corticosteroids)IBA
06/2023 - 01/2008
4Therapeutic UsesIBA
06/2022 - 12/2008
4NivolumabIBA
04/2021 - 01/2018

Therapy/Procedure

102Therapeutics
05/2024 - 09/2002
52Drug Therapy (Chemotherapy)
01/2023 - 09/2005
17Neoadjuvant Therapy
12/2021 - 09/2005
9Radiotherapy
01/2023 - 01/2007
8Aftercare (After-Treatment)
12/2021 - 10/2002
6Adjuvant Chemotherapy
01/2023 - 07/2007
5Hepatectomy
12/2021 - 08/2011
5Lasers (Laser)
05/2021 - 10/2017
4Gastrectomy
01/2022 - 11/2011