Sarah-Maria Fendt Selected Research

Carcinogenesis

1/2021	Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis.
2/2016	Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.

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Sarah-Maria Fendt Research Topics

Disease

50	Neoplasms (Cancer) 05/2024 - 08/2012
12	Neoplasm Metastasis (Metastasis) 03/2024 - 10/2016
11	Breast Neoplasms (Breast Cancer) 03/2024 - 01/2016
3	Melanoma (Melanoma, Malignant) 04/2023 - 01/2018
3	Glioblastoma (Glioblastoma Multiforme) 09/2022 - 01/2020
3	Hypoxia (Hypoxemia) 09/2022 - 01/2013
3	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2019
3	Ischemia 01/2020 - 02/2016
3	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 07/2013
2	Starvation 05/2024 - 11/2021
2	Triple Negative Breast Neoplasms 03/2024 - 10/2020
2	Obesity 01/2023 - 01/2021
2	Carcinoma (Carcinomatosis) 01/2022 - 01/2019
2	Carcinogenesis 01/2021 - 02/2016
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021 - 11/2019
2	Liver Neoplasms (Liver Cancer) 01/2021 - 01/2016
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 11/2019 - 01/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 01/2017
1	Disease Progression 04/2024
1	Frailty 08/2023
1	Pain (Aches) 08/2023
1	Heart Diseases (Heart Disease) 06/2023
1	Pancreatic Neoplasms (Pancreatic Cancer) 06/2023
1	Hyperglycemia 01/2023
1	Fatty Liver 01/2023
1	Insulin Resistance 01/2023
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2022
1	Ovarian Epithelial Carcinoma 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2016
6	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 07/2013
6	LipidsIBA 04/2023 - 01/2017
6	Serine (L-Serine)FDA Link 01/2022 - 08/2012
5	EnzymesIBA 01/2024 - 02/2016
4	Fatty Acids (Saturated Fatty Acids)IBA 05/2024 - 01/2013
4	Mechanistic Target of Rapamycin Complex 1IBA 05/2024 - 05/2013
4	Proline (L-Proline)FDA Link 01/2023 - 11/2017
4	PalmitatesIBA 01/2023 - 01/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 02/2016
3	Phosphotransferases (Kinase)IBA 05/2024 - 01/2021
3	RNA (Ribonucleic Acid)IBA 04/2024 - 10/2019
3	Pyruvic Acid (Pyruvate)IBA 04/2024 - 01/2019
3	Lactic Acid (Lactate)FDA LinkGeneric 04/2024 - 01/2020
3	Methylmalonic AcidIBA 03/2024 - 01/2022
3	Amino Acids FDA Link 01/2021 - 02/2016
3	Messenger RNA (mRNA)IBA 02/2020 - 11/2019
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 01/2018
3	Glutamine (L-Glutamine)FDA Link 01/2017 - 01/2013
2	NAD (NADH)IBA 04/2024 - 01/2022
2	Oxygen (Dioxygen)IBA 01/2023 - 02/2016
2	FructoseIBA 09/2022 - 01/2021
2	Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)IBA 01/2022 - 02/2016
2	Glutathione (Reduced Glutathione)IBA 11/2021 - 02/2020
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2021 - 11/2019
2	CarbonIBA 02/2020 - 01/2013
2	TOR Serine-Threonine KinasesIBA 01/2020 - 10/2014
2	CollagenIBA 01/2019 - 01/2019
2	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2015
1	Eukaryotic Initiation Factor-4EIBA 05/2024
1	Carrier Proteins (Binding Protein)IBA 05/2024
1	Glyceraldehyde 3-Phosphate (Glyceraldehyde 3 Phosphate)IBA 04/2024
1	Oxidoreductases (Dehydrogenase)IBA 04/2024
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 03/2024
1	Phenobarbital (Luminal)FDA Link 03/2024
1	Biomarkers (Surrogate Marker)IBA 08/2023
1	PerhexilineIBA 06/2023
1	Gemcitabine FDA Link 06/2023
1	TVB-3664IBA 04/2023
1	Membrane LipidsIBA 04/2023
1	GoldIBA 04/2023
1	Arsenic Trioxide (Trisenox)FDA Link 04/2023
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 01/2023
1	HexokinaseIBA 01/2023
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2023
1	Lysine AcetyltransferasesIBA 01/2023
1	NF-kappa B (NF-kB)IBA 01/2023
1	Blood Glucose (Blood Sugar)IBA 01/2023
1	Temozolomide (Temodar)FDA LinkGeneric 01/2022
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2022
1	Histones (Histone)IBA 01/2022
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022
1	PlatinumIBA 01/2022
1	PropionatesIBA 01/2022
1	ProteomeIBA 11/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2021
1	Tricarboxylic AcidsIBA 11/2021
1	PhosphoenolpyruvateIBA 11/2021
1	Sertraline (Zoloft)FDA LinkGeneric 01/2021
1	IronIBA 01/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	Thimerosal (Thiomersal)IBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021

Therapy/Procedure

14	Therapeutics 08/2023 - 11/2012
4	Drug Therapy (Chemotherapy) 06/2023 - 01/2021
2	Immunotherapy 01/2020 - 01/2019
1	Precision Medicine 04/2024
1	Activities of Daily Living (ADL) 08/2023
1	Polypharmacy 08/2023
1	Radiotherapy 01/2021