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Thomas Efferth Selected Research

Complex Mixtures

2/2023Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines.
5/2022Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro.
9/2021Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against multidrug-resistant bacteria expressing active efflux pumps.
3/2021Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells.
5/2019Cytotoxicity of the crude extract and constituents of the bark of Fagara tessmannii towards multi-factorial drug resistant cancer cells.
1/2019Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells.
5/2017Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes.
12/2015Cytotoxicity of compounds from Xylopia aethiopica towards multi-factorial drug-resistant cancer cells.
11/2015Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.
1/2015Cytotoxic compounds from the fruits of Uapaca togoensis towards multifactorial drug-resistant cancer cells.
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Thomas Efferth Research Topics

Disease

353Neoplasms (Cancer)
05/2024 - 01/2002
99Leukemia
03/2024 - 03/2002
35Breast Neoplasms (Breast Cancer)
03/2023 - 01/2003
31Malaria
12/2023 - 12/2004
30Carcinoma (Carcinomatosis)
01/2023 - 01/2002
27Glioblastoma (Glioblastoma Multiforme)
12/2023 - 05/2003
21Inflammation (Inflammations)
05/2024 - 07/2010
20Neoplasm Metastasis (Metastasis)
09/2023 - 01/2002
18Carcinogenesis
03/2024 - 09/2010
17Infections
07/2023 - 12/2004
14Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2023 - 01/2002
12Multiple Myeloma
11/2023 - 01/2002
12Colonic Neoplasms (Colon Cancer)
02/2022 - 12/2005
11Necrosis
02/2021 - 06/2008
9Adenocarcinoma
09/2023 - 07/2002
9Lung Neoplasms (Lung Cancer)
07/2023 - 02/2002
9Osteoarthritis
10/2022 - 11/2018
9Alzheimer Disease (Alzheimer's Disease)
09/2022 - 10/2015
9Melanoma (Melanoma, Malignant)
07/2022 - 12/2005
8COVID-19
12/2022 - 01/2021
8Pain (Aches)
06/2022 - 01/2013
7Glioma (Gliomas)
12/2023 - 03/2004
7Neuroinflammatory Diseases
04/2023 - 11/2018
7Hepatocellular Carcinoma (Hepatoma)
01/2023 - 01/2013
7Cardiotoxicity
01/2022 - 07/2004
6Heart Failure
12/2023 - 06/2015
6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
11/2023 - 01/2002
6Squamous Cell Carcinoma of Head and Neck
10/2023 - 09/2004
6Prostatic Neoplasms (Prostate Cancer)
01/2023 - 07/2008
6Virus Diseases (Viral Diseases)
11/2022 - 08/2011
5Brain Neoplasms (Brain Tumor)
12/2023 - 07/2010
5Opioid-Related Disorders (Opiate Addiction)
12/2022 - 01/2021
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2022 - 02/2002
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2022 - 06/2015

Drug/Important Bio-Agent (IBA)

56Proteins (Proteins, Gene)FDA Link
04/2024 - 01/2002
54ArtesunateIBA
12/2023 - 03/2002
53Member 1 Subfamily B ATP Binding Cassette TransporterIBA
09/2023 - 01/2003
49Doxorubicin (Adriamycin)FDA LinkGeneric
06/2023 - 07/2002
43artemisinin (artemisinine)IBA
03/2023 - 08/2002
30ATP-Binding Cassette Transporters (ABC Transporters)IBA
03/2023 - 12/2004
29PhytochemicalsIBA
01/2023 - 07/2011
26ErbB Receptors (EGF Receptor)IBA
04/2022 - 05/2003
25resazurinIBA
08/2023 - 01/2012
24Antimalarials (Antimalarial Agents)IBA
07/2017 - 08/2003
23Messenger RNA (mRNA)IBA
09/2022 - 08/2002
20AntioxidantsIBA
01/2023 - 10/2003
15Plant ExtractsIBA
10/2023 - 03/2004
15Methanol (Carbinol)IBA
09/2023 - 04/2011
14AlkaloidsIBA
03/2024 - 04/2010
14Antiviral Agents (Antivirals)IBA
11/2022 - 04/2002
14FlavonoidsIBA
07/2022 - 12/2011
12EnzymesIBA
03/2024 - 08/2003
12Antineoplastic Agents (Antineoplastics)IBA
11/2023 - 10/2010
11DNA (Deoxyribonucleic Acid)IBA
12/2023 - 08/2003
11Complex MixturesIBA
02/2023 - 08/2013
11TeaIBA
06/2022 - 09/2010
10Transcription Factors (Transcription Factor)IBA
03/2023 - 04/2010
10Biomarkers (Surrogate Marker)IBA
01/2023 - 08/2010
10ArtemisininsIBA
01/2023 - 07/2004
10Adenosine Triphosphate (ATP)IBA
01/2022 - 12/2004
9Volatile Oils (Essential Oils)IBA
04/2023 - 08/2009
9shikoninIBA
02/2022 - 01/2012
9CaspasesIBA
12/2021 - 08/2010
9Reactive Oxygen Species (Oxygen Radicals)IBA
09/2018 - 11/2006
8AcidsIBA
01/2023 - 04/2015
8CytokinesIBA
12/2022 - 05/2003
8Matrix Metalloproteinases (MMPs)IBA
09/2018 - 09/2010
7Paclitaxel (Taxol)FDA LinkGeneric
02/2023 - 07/2008
7Phosphotransferases (Kinase)IBA
01/2023 - 04/2010
7Opioid Analgesics (Opioids)IBA
12/2022 - 01/2013
7CurcuminIBA
04/2022 - 12/2009
7NaphthoquinonesIBA
01/2022 - 05/2010
7Tyrosine Kinase InhibitorsIBA
11/2021 - 03/2004
7IronIBA
01/2020 - 10/2004
6EstersIBA
05/2024 - 10/2013
6Cisplatin (Platino)FDA LinkGeneric
10/2023 - 12/2002
6XenobioticsIBA
03/2023 - 01/2015
6Plant Preparations (Preparation, Plant)IBA
09/2022 - 05/2015
6theabrowninIBA
06/2022 - 01/2016
6multidrug resistance-associated protein 1IBA
01/2022 - 01/2003
6Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 08/2003
6Cytostatic AgentsIBA
11/2019 - 01/2003
6Cantharidin (Cantharides)IBA
02/2014 - 03/2005
5Therapeutic UsesIBA
03/2024 - 06/2008
5Temozolomide (Temodar)FDA LinkGeneric
12/2023 - 04/2013
5SesquiterpenesIBA
01/2023 - 12/2004
5Peptide Hydrolases (Proteases)FDA Link
01/2023 - 09/2010
5RNA (Ribonucleic Acid)IBA
01/2023 - 01/2020
5Translationally-Controlled 1 Tumor ProteinIBA
11/2022 - 02/2005
5CamptothecinIBA
07/2022 - 03/2008
5ResveratrolIBA
01/2021 - 10/2009
5Chalcone (Benzalacetophenone)IBA
09/2019 - 09/2010
5Arsenic Trioxide (Trisenox)FDA Link
01/2018 - 09/2004

Therapy/Procedure

135Therapeutics
04/2024 - 04/2002
101Drug Therapy (Chemotherapy)
05/2024 - 03/2004
24Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2023 - 03/2002
9Chemoprevention
07/2023 - 03/2006
6Radiotherapy
07/2022 - 03/2008
6Traditional Medicine (Folk Remedies)
03/2022 - 07/2007
5Precision Medicine
04/2024 - 01/2015