Wuguo Deng Selected Research

Lung Neoplasms (Lung Cancer)

9/2023	Correction: Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells.
11/2021	Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells.
1/2020	PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
4/2019	Sequence-dependent synergistic cytotoxicity of icotinib and pemetrexed in human lung cancer cell lines in vitro and in vivo.
10/2017	Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas.
1/2017	β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
10/2016	Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
5/2016	Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death.
4/2016	hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers.
2/2016	CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.

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Wuguo Deng Research Topics

Disease

70	Neoplasms (Cancer) 06/2023 - 07/2007
23	Lung Neoplasms (Lung Cancer) 09/2023 - 07/2007
15	Neoplasm Metastasis (Metastasis) 06/2023 - 01/2014
13	Breast Neoplasms (Breast Cancer) 06/2023 - 01/2011
13	Nasopharyngeal Carcinoma 01/2023 - 01/2012
10	Adenocarcinoma of Lung 01/2021 - 01/2013
8	Melanoma (Melanoma, Malignant) 01/2021 - 01/2013
7	Carcinogenesis 09/2022 - 10/2014
6	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 01/2016
6	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2013
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020 - 07/2007
4	Inflammation (Inflammations) 01/2023 - 01/2011
4	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 01/2017
4	Carcinoma (Carcinomatosis) 10/2020 - 06/2014
3	Hypertrophic Cicatrix (Hypertrophic Scar) 01/2024 - 01/2017
3	Fibrosis (Cirrhosis) 01/2024 - 01/2017
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2023 - 01/2020
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2020 - 01/2016
2	Thyroid Neoplasms (Thyroid Cancer) 11/2023 - 01/2021
2	Wounds and Injuries (Trauma) 10/2023 - 01/2023
2	Triple Negative Breast Neoplasms 06/2023 - 01/2023
2	Keloid 01/2023 - 01/2023
2	Infections 01/2023 - 07/2014
2	Squamous Cell Carcinoma of Head and Neck 01/2021 - 06/2014
2	Leukemia 01/2019 - 01/2019
2	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 01/2017
2	Adenocarcinoma 01/2016 - 01/2015
1	Hyperglycemia 10/2023
1	Salpingitis 01/2023
1	Ulcer 01/2023
1	Infertility (Sterility) 01/2023
1	Diabetic Foot 01/2023

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 06/2023 - 07/2007
15	MelatoninIBA 01/2024 - 08/2012
15	Small Interfering RNA (siRNA)IBA 01/2019 - 01/2013
14	CaspasesIBA 01/2020 - 07/2007
11	Telomerase (Telomerase Reverse Transcriptase)IBA 03/2022 - 05/2014
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2013
7	Cytochromes c (Cytochrome c)IBA 01/2018 - 01/2013
6	Messenger RNA (mRNA)IBA 02/2023 - 01/2011
6	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 06/2014
6	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2017 - 01/2011
5	Carrier Proteins (Binding Protein)IBA 01/2017 - 10/2014
4	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2018
4	Fluorouracil (Carac)FDA LinkGeneric 09/2022 - 03/2017
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 01/2012
4	Dinoprostone (PGE2)FDA Link 10/2017 - 08/2012
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2014 - 01/2012
3	Epirubicin (Ellence)FDA LinkGeneric 06/2023 - 01/2021
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2017
3	CateninsIBA 01/2020 - 01/2017
3	EnzymesIBA 01/2020 - 01/2016
3	LuciferasesIBA 02/2019 - 10/2014
3	Caspase 3 (Caspase-3)IBA 10/2017 - 01/2013
2	bufadienolideIBA 09/2023 - 08/2014
2	gamabufotalinIBA 09/2023 - 08/2014
2	Amphibian VenomsIBA 09/2023 - 08/2014
2	VemurafenibIBA 01/2021 - 02/2019
2	Proto-Oncogene Proteins B-rafIBA 01/2021 - 02/2019
2	Nuclear Receptor Coactivator 3IBA 11/2020 - 01/2018
2	RNA Splicing FactorsIBA 01/2020 - 01/2020
2	Poly UIBA 01/2020 - 01/2020
2	palbociclibIBA 10/2019 - 12/2015
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 02/2019 - 11/2014
2	Indicators and Reagents (Reagents)IBA 08/2017 - 01/2015
2	B7-H1 AntigenIBA 08/2017 - 01/2017
2	Biotin (Vitamin H)FDA Link 01/2017 - 10/2014
2	streptavidin-agaroseIBA 01/2017 - 01/2017
2	CREB-Binding ProteinIBA 01/2017 - 02/2016
2	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2017 - 04/2016
2	Sirolimus (Rapamycin)FDA Link 05/2016 - 07/2014
2	BerberineIBA 01/2016 - 01/2013
2	ChromatinIBA 12/2014 - 10/2014
2	Ursolic AcidIBA 05/2013 - 01/2013
1	Hormones (Hormone)IBA 01/2024
1	MT2 Melatonin ReceptorIBA 01/2024
1	raf KinasesIBA 11/2023
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 10/2023
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 01/2023
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2023
1	phenylpyruvic acidIBA 01/2023
1	Protein Deglycase DJ-1IBA 01/2023
1	TensinsIBA 01/2023
1	7- chloro- 8- hydroxy- 1- (3'- iodophenyl)- 3- methyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepine (TISCH)IBA 01/2023
1	Interleukin-18 (Interleukin 18)IBA 01/2023
1	InflammasomesIBA 01/2023
1	CytokinesIBA 01/2023
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2023
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2023
1	Immune Checkpoint ProteinsIBA 01/2023
1	Sincalide FDA Link 01/2023
1	CollagenIBA 01/2023
1	NADP (NADPH)IBA 12/2022
1	Progesterone Receptors (Progesterone Receptor)IBA 09/2022

Therapy/Procedure

18	Therapeutics 01/2023 - 01/2013
11	Drug Therapy (Chemotherapy) 01/2023 - 01/2012
8	Radiotherapy 01/2023 - 01/2013
4	Immunotherapy 01/2023 - 01/2020
3	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 08/2016 - 12/2015
1	Conservative Treatment 11/2023