Erdem Coskun Selected Research

Neoplasms (Cancer)

1/2021	Inhibition by Tetrahydroquinoline Sulfonamide Derivatives of the Activity of Human 8-Oxoguanine DNA Glycosylase (OGG1) for Several Products of Oxidatively induced DNA Base Lesions.
1/2019	Identification and quantification of DNA repair protein poly(ADP ribose) polymerase 1 (PARP1) in human tissues and cultured cells by liquid chromatography/isotope-dilution tandem mass spectrometry.
1/2017	Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics.
1/2016	Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements.
10/2015	Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).
9/2015	Addiction to MTH1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry.
3/2011	Micronucleus frequencies in lymphocytes and buccal epithelial cells from patients having head and neck cancer and their first-degree relatives.
3/2010	Increased micronucleus frequencies in surrogate and target cells from workers exposed to crystalline silica-containing dust.

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Erdem Coskun Research Topics

Disease

8	Neoplasms (Cancer) 01/2021 - 03/2010
2	Carcinogenesis 01/2022 - 01/2019
2	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2019
2	Inflammation (Inflammations) 01/2019 - 12/2018
2	Ischemia 01/2017 - 01/2017
2	Breast Neoplasms (Breast Cancer) 09/2015 - 09/2015
1	Chromosome Breakage 06/2023
1	Glomerulonephritis 01/2021
1	Infections 01/2019
1	Hepatitis B 01/2019
1	Pneumonia (Pneumonitis) 12/2018
1	Chromosome Aberrations (Chromosome Abnormalities) 10/2012

Drug/Important Bio-Agent (IBA)

10	DNA (Deoxyribonucleic Acid)IBA 06/2023 - 10/2012
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 03/2011
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 09/2015
2	DNA Glycosylases (DNA Glycosylase)IBA 01/2021 - 01/2017
2	Aflatoxin B1 (Aflatoxin B)IBA 01/2019 - 01/2019
2	Propofol (Diprivan)FDA LinkGeneric 01/2017 - 01/2017
2	Sevoflurane (Ultane)FDA LinkGeneric 01/2017 - 01/2017
2	IsotopesIBA 09/2015 - 09/2015
1	pyrimidineIBA 01/2022
1	purineIBA 01/2022
1	Antinuclear AntibodiesIBA 01/2021
1	AflatoxinsIBA 01/2019
1	DNA AdductsIBA 01/2019
1	8-hydroxyguanineIBA 10/2015
1	EnzymesIBA 10/2015
1	EndonucleasesIBA 09/2015
1	Bleomycin (Blenoxane)FDA LinkGeneric 10/2012
1	Silicon Dioxide (Silica)FDA LinkGeneric 03/2010
1	CarcinogensIBA 03/2010
1	QuartzIBA 03/2010

Therapy/Procedure

6	Therapeutics 01/2021 - 09/2015
2	Anesthesia 01/2017 - 01/2017
2	Tourniquets 01/2017 - 01/2017