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Paul M Clement Selected Research

monomethylauristatin F

1/2020INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma.

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Paul M Clement Research Topics

Disease

18Neoplasms (Cancer)
03/2024 - 03/2009
13Glioblastoma (Glioblastoma Multiforme)
10/2023 - 03/2009
9Squamous Cell Carcinoma of Head and Neck
03/2024 - 05/2015
7Glioma (Gliomas)
01/2023 - 11/2016
6Neuroendocrine Tumors (Neuroendocrine Tumor)
06/2023 - 01/2020
5Neoplasm Metastasis (Metastasis)
06/2022 - 06/2016
4Astrocytoma (Pilocytic Astrocytoma)
03/2024 - 11/2016
4Fatigue
01/2022 - 05/2015
3Brain Neoplasms (Brain Tumor)
05/2023 - 03/2009
2Head and Neck Neoplasms (Head and Neck Cancer)
01/2023 - 01/2022
2Inflammation (Inflammations)
01/2022 - 01/2020
2Stomatitis
10/2019 - 05/2015
2Acne Vulgaris
10/2019 - 05/2015
2Exanthema (Rash)
10/2019 - 05/2015
2Carcinoma (Carcinomatosis)
12/2016 - 06/2016
1Cachexia
01/2023
1Thrombocytopenia (Thrombopenia)
01/2023
1Weight Loss (Weight Reduction)
01/2023
1Neuroblastoma
01/2023
1Paraganglioma (Paragangliomas)
01/2023
1Renal Cell Carcinoma (Grawitz Tumor)
01/2022
1Carcinogenesis
01/2022
1Meningioma (Meningiomas)
01/2022
1Central Nervous System Neoplasms
01/2022
1Hypersensitivity (Allergy)
01/2020
1Necrosis
11/2019
1Nausea
10/2019
1Diarrhea
10/2019
1Osteonecrosis (Kienbock's Disease)
04/2018
1Ewing Sarcoma (Sarcoma, Ewing)
01/2017

Drug/Important Bio-Agent (IBA)

13Temozolomide (Temodar)FDA LinkGeneric
03/2024 - 03/2009
7Lomustine (CCNU)FDA Link
10/2023 - 11/2017
7Bevacizumab (Avastin)FDA Link
10/2023 - 03/2015
4Immune Checkpoint InhibitorsIBA
12/2023 - 01/2022
4Biomarkers (Surrogate Marker)IBA
10/2023 - 01/2020
4LigandsIBA
01/2022 - 12/2016
4ErbB Receptors (EGF Receptor)IBA
01/2020 - 03/2009
3AfatinibIBA
10/2023 - 05/2015
3Somatostatin Receptors (Somatostatin Receptor)IBA
01/2023 - 06/2020
3Radioisotopes (Radionuclides)IBA
01/2022 - 01/2020
3Peptide Receptors (Peptide Receptor)IBA
01/2022 - 01/2020
3depatuxizumab mafodotinIBA
08/2021 - 01/2020
2RNA (Ribonucleic Acid)IBA
03/2024 - 10/2023
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
10/2023 - 01/2022
2Immunoconjugates (Immunoconjugate)IBA
01/2020 - 01/2020
2epidermal growth factor receptor VIIIIBA
01/2020 - 03/2009
2Tyrosine Kinase InhibitorsIBA
01/2020 - 05/2015
2Carboplatin (JM8)FDA LinkGeneric
01/2020 - 12/2016
2Methotrexate (Mexate)FDA LinkGeneric
10/2019 - 05/2015
2PlatinumIBA
01/2019 - 05/2015
2Cisplatin (Platino)FDA LinkGeneric
01/2017 - 12/2016
2IfosfamideFDA LinkGeneric
01/2017 - 06/2016
1B7-H1 AntigenIBA
03/2024
1AntibodiesIBA
03/2024
1Programmed Cell Death 1 ReceptorIBA
10/2023
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2023
1Octreotide (Sandostatin)FDA LinkGeneric
06/2023
11,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA
06/2023
1AMG232IBA
05/2023
1Complement System Proteins (Complement)IBA
05/2023
13-Iodobenzylguanidine (Iobenguane)IBA
01/2023
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2023
1AntigensIBA
01/2023
1Peptides (Polypeptides)IBA
06/2022
1Alkaline PhosphataseIBA
06/2022
1Serum AlbuminIBA
06/2022
1Phosphotransferases (Kinase)IBA
01/2022
1Proteins (Proteins, Gene)FDA Link
01/2022
1Angiogenesis InhibitorsIBA
01/2022
1TrabectedinIBA
01/2022
1larotrectinibIBA
01/2022
1tyrosine receptor (receptor, tyrosine)IBA
01/2022
1Edotreotide (SMT 487)IBA
01/2022
1TropomyosinIBA
01/2022
1EpitopesIBA
01/2020
1NVP-BKM120IBA
01/2020
1NucleotidesIBA
01/2020
1monomethylauristatin FIBA
01/2020
1Ga(III)-DOTATOCIBA
01/2020
1DOTA-Tyr(3)- 90Y-octreotideIBA
01/2020
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2020
1Monoclonal AntibodiesIBA
01/2019
1durvalumabIBA
01/2019
1DenosumabFDA Link
04/2018
1Diphosphonates (Bisphosphonates)IBA
04/2018
1Bone Density Conservation AgentsIBA
04/2018
1Etoposide (VP 16)FDA LinkGeneric
01/2017
1Vincristine (Oncovin)FDA LinkGeneric
01/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2017
1Fluorouracil (Carac)FDA LinkGeneric
12/2016

Therapy/Procedure

11Therapeutics
03/2024 - 05/2015
10Radiotherapy
05/2023 - 05/2015
9Drug Therapy (Chemotherapy)
01/2023 - 06/2016
2Precision Medicine
01/2022 - 10/2019
2Palliative Care (Palliative Therapy)
06/2016 - 01/2014
1Immunotherapy
01/2023
1Drug Tapering
01/2023
1Conformal Radiotherapy
01/2021
1Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
01/2021
1Neoadjuvant Therapy
01/2017