Kin-Chow Chang Selected Research

Antiviral Agents (Antivirals)

1/2022	Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals.
12/2021	Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin.
1/2021	Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus.
1/2021	IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
1/2020	Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication.
1/2014	High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance.

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Kin-Chow Chang Research Topics

Disease

12	Infections 07/2022 - 01/2010
9	Influenza in Birds (Avian Flu) 07/2022 - 11/2014
5	Human Influenza (Influenza) 12/2021 - 01/2010
1	Coinfection 12/2021
1	Virus Diseases (Viral Diseases) 01/2020
1	Blister (Bulla) 03/2015
1	Bites and Stings (Sting) 01/2014
1	Hypertrophy 01/2009

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 07/2022 - 08/2015
6	Antiviral Agents (Antivirals)IBA 01/2022 - 01/2014
4	RNA (Ribonucleic Acid)IBA 12/2021 - 10/2012
3	Viral RNAIBA 12/2021 - 10/2018
2	VaccinesIBA 01/2021 - 01/2020
2	Virulence Factors (Pathogenicity Factors)IBA 12/2015 - 11/2014
1	Hemagglutinins (Hemagglutinin)IBA 07/2022
1	AerosolsIBA 12/2021
1	AcidsIBA 01/2021
1	Interferon Type IIBA 10/2018
1	sialic acid receptorIBA 01/2016
1	NucleoproteinsIBA 03/2015
1	IFIH1 Interferon-Induced HelicaseIBA 03/2015
1	Matrix-MIBA 03/2015
1	Interferon-betaIBA 03/2015
1	Annexin A5IBA 03/2015
1	Caspase 3 (Caspase-3)IBA 03/2015
1	InterferonsIBA 01/2014
1	CytokinesIBA 09/2012
1	Chemokine CXCL9IBA 09/2012
1	ChemokinesIBA 09/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2012
1	Interleukin-6 (Interleukin 6)IBA 09/2012
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2010
1	Virus ReceptorsIBA 01/2010
1	CalcineurinIBA 01/2009
1	EnzymesIBA 01/2009
1	Ion Channels (Ion Channel)IBA 01/2009

Therapy/Procedure

1	Oral Administration 01/2020