Ricardo Castro Selected Research

Septic Shock (Toxic Shock Syndrome)

4/2024	Capillary refill time response to a fluid challenge or a vasopressor test: an observational, proof-of-concept study.
1/2023	Exploring the relationship between capillary refill time, skin blood flow and microcirculatory reactivity during early resuscitation of patients with septic shock: a pilot study.
2/2022	Current practice and evolving concepts in septic shock resuscitation.
1/2022	Hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial study protocol.
11/2020	Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial.
8/2020	A lactate-targeted resuscitation strategy may be associated with higher mortality in patients with septic shock and normal capillary refill time: a post hoc analysis of the ANDROMEDA-SHOCK study.
6/2020	Hypoxia-related parameters during septic shock resuscitation: Pathophysiological determinants and potential clinical implications.
6/2020	Optimal target in septic shock resuscitation.
1/2020	Systematic assessment of fluid responsiveness during early septic shock resuscitation: secondary analysis of the ANDROMEDA-SHOCK trial.
1/2020	Effects of a Resuscitation Strategy Targeting Peripheral Perfusion Status versus Serum Lactate Levels among Patients with Septic Shock. A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial.

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Ricardo Castro Research Topics

Disease

25	Septic Shock (Toxic Shock Syndrome) 04/2024 - 05/2006
10	Shock 05/2024 - 08/2016
8	COVID-19 01/2023 - 01/2021
8	Hyperlactatemia 12/2017 - 08/2011
5	Infections 01/2023 - 03/2020
5	Sepsis (Septicemia) 01/2017 - 08/2011
3	Critical Illness (Critically Ill) 01/2024 - 01/2009
2	Inflammation (Inflammations) 01/2023 - 01/2021
2	Anastomotic Leak 11/2022 - 06/2022
2	Respiratory Insufficiency (Respiratory Failure) 10/2021 - 01/2021
2	Hypoxia (Hypoxemia) 11/2020 - 06/2020
2	Hypotension (Low Blood Pressure) 01/2016 - 05/2006
2	Thrombosis (Thrombus) 03/2012 - 01/2012
1	Hyperemia 01/2024
1	Respiratory Tract Infections (Respiratory Tract Infection) 09/2022
1	Coinfection 09/2022
1	Alopecia (Baldness) 06/2021
1	Acne Vulgaris 06/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 06/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 03/2020
1	Myocarditis (Carditis) 03/2020
1	Cardiomyopathies (Cardiomyopathy) 03/2020
1	Bronchiectasis 03/2019
1	Heart Failure 01/2019
1	Soft Tissue Infections 09/2018
1	Sialadenitis 12/2015
1	Thyroid Neoplasms (Thyroid Cancer) 12/2015
1	Low Cardiac Output 08/2013
1	Heart Arrest (Cardiac Arrest) 07/2012
1	Embolism (Embolus) 03/2012
1	Pulmonary Embolism 03/2012
1	Lung Injury 03/2012
1	Intra-Abdominal Hypertension 12/2008
1	Lactic Acidosis 05/2006
1	Osteoarthritis 01/2002

Drug/Important Bio-Agent (IBA)

12	Lactic Acid (Lactate)FDA LinkGeneric 11/2020 - 08/2011
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2024 - 05/2006
3	InflammasomesIBA 01/2023 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2021
2	Interleukin-18 (Interleukin 18)IBA 01/2023 - 01/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2022 - 08/2016
2	Biomarkers (Surrogate Marker)IBA 06/2020 - 03/2012
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2022
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 06/2022
1	C-Reactive ProteinIBA 06/2022
1	Immunomodulating AgentsIBA 01/2022
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2021
1	Liposomes (Liposome)IBA 06/2021
1	AlbuminsIBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 06/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2020
1	Methicillin (Metin)FDA Link 03/2020
1	TroponinIBA 03/2020
1	trans-crotonin (CTN)IBA 03/2020
1	Heterophile AntibodiesIBA 03/2020
1	CarbonIBA 09/2018
1	Ionic LiquidsIBA 09/2018
1	imidazoleIBA 09/2018
1	Protein CIBA 12/2016
1	Hydrocortisone (Cortisol)FDA LinkGeneric 08/2016
1	esmolol (Brevibloc)FDA LinkGeneric 01/2016
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2016
1	Dexmedetomidine FDA Link 01/2016
1	EndotoxinsIBA 01/2016
1	SteroidsIBA 12/2015
1	Dobutamine FDA LinkGeneric 08/2013
1	pro-brain natriuretic peptide (1-76)IBA 03/2012
1	Brain Natriuretic Peptide (Natrecor)FDA Link 03/2012
1	Adenosine (Adenocard)FDA LinkGeneric 01/2012
1	CreatinineIBA 12/2008
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2002
1	EtoricoxibIBA 01/2002

Therapy/Procedure

25	Resuscitation 04/2024 - 01/2009
5	Length of Stay 09/2022 - 03/2019
4	Artificial Respiration (Mechanical Ventilation) 05/2024 - 01/2021
3	Therapeutics 02/2022 - 12/2015
2	Early Goal-Directed Therapy 07/2018 - 04/2018
2	Controlled Hypotension 01/2012 - 08/2011
1	Critical Care (Surgical Intensive Care) 01/2024
1	Patient Readmission 11/2022
1	Cannula 11/2021
1	Urinary Catheters 03/2020
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2019
1	Radiotherapy 12/2015
1	Catheters 03/2012
1	Hemofiltration 05/2006
1	Salvage Therapy 05/2006