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Beatrice Cardinali Selected Research

Myotonic Dystrophy (Dystrophia Myotonica)

4/2022Molecular Therapies for Myotonic Dystrophy Type 1: From Small Drugs to Gene Editing.
3/2022Time-controlled and muscle-specific CRISPR/Cas9-mediated deletion of CTG-repeat expansion in the DMPK gene.
1/2021Design of novel small molecule base-pair recognizers of toxic CUG RNA transcripts characteristics of DM1.
1/2018High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2.

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Beatrice Cardinali Research Topics

Disease

7Neoplasms (Cancer)
08/2022 - 02/2002
4Myotonic Dystrophy (Dystrophia Myotonica)
04/2022 - 01/2018
3Neuroblastoma
01/2018 - 02/2002
2Neoplasm Metastasis (Metastasis)
06/2020 - 01/2012
1Glioblastoma (Glioblastoma Multiforme)
08/2022
1Brain Neoplasms (Brain Tumor)
06/2020
1Melanoma (Melanoma, Malignant)
06/2020
1Disease Progression
06/2020
1Colorectal Neoplasms (Colorectal Cancer)
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2017
1Medulloblastoma
10/2015
1Lung Neoplasms (Lung Cancer)
01/2015
1Ovarian Neoplasms (Ovarian Cancer)
01/2015

Drug/Important Bio-Agent (IBA)

2MicroRNAs (MicroRNA)IBA
08/2022 - 06/2020
23' Untranslated Regions (3' UTR)IBA
03/2022 - 01/2021
2Biomarkers (Surrogate Marker)IBA
06/2020 - 01/2012
1Oncogene Proteins (Oncogene Protein)IBA
08/2022
1ProteomeIBA
08/2022
1Proteins (Proteins, Gene)FDA Link
08/2022
16- (4- hydroxyphenyl)- 2- thioxo- 2,3- dihydro- 4(1H)- pyrimidinoneIBA
01/2018
1DNA (Deoxyribonucleic Acid)IBA
01/2018
1RNA-Induced Silencing ComplexIBA
01/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1ErbB Receptors (EGF Receptor)IBA
11/2017
1PolyaminesIBA
10/2015
1Tyrosine Kinase InhibitorsIBA
01/2015
1Galectin 3 (LGALS3)IBA
01/2012
1nutlin 3IBA
01/2012
1Oxidoreductases (Dehydrogenase)IBA
02/2002
1alcohol dehydrogenase (NAD(P)+)IBA
02/2002
1retinol dehydrogenaseIBA
02/2002
1RetinoidsIBA
02/2002
1Tretinoin (Retinoic Acid)FDA LinkGeneric
02/2002
1Vitamin A (Retinol)FDA LinkGeneric
02/2002

Therapy/Procedure

4Therapeutics
04/2022 - 01/2012
1Aftercare (After-Treatment)
02/2021
1Molecular Targeted Therapy
01/2015
1Combined Modality Therapy
01/2012