Ali Calderon-Aparicio Selected Research

Neoplasms (Cancer)

12/2021	Prostate cancer: Alternatively spliced mRNA transcripts in tumor progression and their uses as therapeutic targets.
2/2021	Roles of regulator of chromosome condensation 2 in cancer: Beyond its regulatory function in cell cycle.
12/2020	Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function.
11/2020	RCC2 Promotes Esophageal Cancer Growth by Regulating Activity and Expression of the Sox2 Transcription Factor.
1/2019	Anticancer response to disulfiram may be enhanced by co-treatment with MEK inhibitor or oxaliplatin: modulation by tetrathiomolybdate, KRAS/BRAF mutations and c-MYC/p53 status.
10/2015	Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H2O2 generation: antagonism by tetrathiomolybdate.

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Ali Calderon-Aparicio Research Topics

Disease

6	Neoplasms (Cancer) 12/2021 - 10/2015
2	Melanoma (Melanoma, Malignant) 01/2019 - 10/2015
1	Prostatic Neoplasms (Prostate Cancer) 12/2021
1	Neoplasm Metastasis (Metastasis) 12/2021
1	Colonic Neoplasms (Colon Cancer) 12/2020
1	Esophageal Neoplasms (Esophageal Cancer) 11/2020
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019
1	Breast Neoplasms (Breast Cancer) 10/2015

Drug/Important Bio-Agent (IBA)

2	Transcription Factors (Transcription Factor)IBA 02/2021 - 11/2020
2	tetrathiomolybdate (ammonium tetrathiomolybdate)IBA 01/2019 - 10/2015
2	Disulfiram (Antabuse)FDA Link 01/2019 - 10/2015
2	Chelating AgentsIBA 01/2019 - 10/2015
2	CopperIBA 01/2019 - 10/2015
1	ProteomeIBA 12/2021
1	Messenger RNA (mRNA)IBA 12/2021
1	Biomarkers (Surrogate Marker)IBA 02/2021
1	ERRalpha Estrogen-Related ReceptorIBA 12/2020
1	SOXB1 Transcription FactorsIBA 11/2020
1	Proteins (Proteins, Gene)FDA Link 11/2020
1	neocuproineIBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019
1	EnzymesIBA 01/2019
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019
1	U 0126 (UO 126)IBA 01/2019
1	1,10-phenanthrolineIBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2015

Therapy/Procedure

3	Therapeutics 12/2021 - 01/2019
1	Radiotherapy 02/2021
1	Drug Therapy (Chemotherapy) 02/2021