Frances L Byrne Selected Research

Endometrial Neoplasms (Endometrial Cancer)

3/2024	The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues.
3/2023	Investigation of circular RNA transcriptome in obesity-related endometrial cancer.
9/2022	Investigation of Transcriptome Patterns in Endometrial Cancers from Obese and Lean Women.
4/2022	Differences in the Active Endometrial Microbiota across Body Weight and Cancer in Humans and Mice.
5/2020	The Role of Hyperglycemia in Endometrial Cancer Pathogenesis.
1/2020	The NF-κB signalling pathway regulates GLUT6 expression in endometrial cancer.
1/2018	Analysis of the circular RNA transcriptome in endometrial cancer.
1/2018	Knockout of glucose transporter GLUT6 has minimal effects on whole body metabolic physiology in mice.
12/2017	Transcriptome landscape of long intergenic non-coding RNAs in endometrial cancer.
10/2014	Metabolic vulnerabilities in endometrial cancer.

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Frances L Byrne Research Topics

Disease

20	Neoplasms (Cancer) 03/2024 - 04/2014
10	Endometrial Neoplasms (Endometrial Cancer) 03/2024 - 10/2014
10	Obesity 01/2024 - 04/2014
5	Liver Neoplasms (Liver Cancer) 01/2024 - 07/2014
5	Fatty Liver 01/2024 - 07/2014
4	Hyperglycemia 01/2023 - 02/2016
4	Carcinogenesis 09/2018 - 01/2015
3	Insulin Resistance 08/2022 - 03/2015
3	Neoplasm Metastasis (Metastasis) 04/2022 - 01/2015
2	Hypoxia (Hypoxemia) 03/2024 - 01/2023
2	Body Weight (Weight, Body) 01/2024 - 01/2023
2	Hypertriglyceridemia 01/2024 - 01/2023
2	Weight Loss (Weight Reduction) 01/2024 - 01/2023
2	Neuroblastoma 01/2022 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2020 - 10/2019
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2017 - 10/2015
2	Glucose Intolerance 02/2016 - 03/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2015 - 01/2011
1	Metabolic Diseases (Metabolic Disease) 01/2023
1	Hepatocellular Carcinoma (Hepatoma) 04/2022
1	Diabetes Mellitus 11/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2020
1	Prediabetic State (Prediabetes) 11/2020
1	Atherosclerosis 11/2020
1	Sepsis (Septicemia) 05/2020
1	Necrosis 01/2020
1	Type 2 Diabetes Mellitus (MODY) 06/2017
1	Overnutrition 02/2016
1	Hyperinsulinism (Hyperinsulinemia) 02/2016
1	Adenocarcinoma 02/2015
1	Pancreatic Neoplasms (Pancreatic Cancer) 02/2015

Drug/Important Bio-Agent (IBA)

7	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 06/2017
7	Proteins (Proteins, Gene)FDA Link 09/2022 - 01/2015
4	EnzymesIBA 03/2024 - 07/2014
4	Biomarkers (Surrogate Marker)IBA 09/2022 - 10/2016
3	CholesterolIBA 03/2024 - 11/2020
3	Long Noncoding RNAIBA 09/2022 - 10/2016
3	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 08/2022 - 10/2014
3	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2011
3	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 11/2021 - 03/2015
3	Insulin (Novolin)FDA Link 01/2020 - 03/2015
3	Dietary SugarsIBA 09/2018 - 03/2015
2	Squalene Monooxygenase (Squalene Epoxidase)IBA 03/2024 - 01/2023
2	Oxygen (Dioxygen)IBA 03/2024 - 01/2023
2	semaglutideIBA 01/2024 - 01/2024
2	Circular RNAIBA 03/2023 - 01/2018
2	mitochondrial uncoupler BAM15IBA 01/2023 - 01/2020
2	RNA (Ribonucleic Acid)IBA 09/2022 - 12/2017
2	Blood Glucose (Blood Sugar)IBA 08/2022 - 05/2020
2	AntioxidantsIBA 05/2020 - 01/2017
2	Glutamine (L-Glutamine)FDA Link 01/2020 - 10/2019
2	SugarsIBA 02/2016 - 03/2015
2	CarcinogensIBA 02/2016 - 03/2015
2	LipidsIBA 02/2016 - 07/2014
2	Dietary Fats (Dietary Fat)IBA 02/2016 - 03/2015
2	TubulinIBA 01/2015 - 01/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2014 - 04/2014
1	SterolsIBA 03/2024
1	Rosiglitazone (Avandia)FDA Link 01/2024
1	FructoseIBA 01/2024
1	SqualeneIBA 01/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2023
1	16S Ribosomal RNAIBA 04/2022
1	Sulfoglycosphingolipids (Sulfatides)IBA 04/2022
1	GlycosphingolipidsIBA 04/2022
1	GlobosidesIBA 04/2022
1	GangliosidesIBA 04/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022
1	Polysaccharides (Glycans)IBA 01/2022
1	StathminIBA 01/2022
1	ceramide glucosyltransferaseIBA 11/2021
1	Therapeutic UsesIBA 01/2021
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 11/2020
1	Receptor for Advanced Glycation End ProductsIBA 11/2020
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 05/2020
1	Tocopherols (Tocopherol)IBA 05/2020
1	QuinonesIBA 01/2020
1	tanespimycin (17AAG)IBA 01/2020
1	NaphthoquinonesIBA 01/2020
1	CytokinesIBA 01/2020
1	1,4-naphthoquinoneIBA 01/2020
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2020
1	Vitamin K 3 (Menadione)FDA Link 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	SphingolipidsIBA 10/2019
1	Hemoglobins (Hemoglobin)IBA 06/2017
1	Messenger RNA (mRNA)IBA 06/2017
1	Estrogens (Estrogen)FDA Link 02/2016
1	LuciferasesIBA 01/2016
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 10/2015
1	Sirolimus (Rapamycin)FDA Link 10/2015
1	Interleukin-6 (Interleukin 6)IBA 03/2015
1	AdiponectinIBA 03/2015
1	lardIBA 03/2015
1	Guanosine Triphosphate (GTP)IBA 02/2015

Therapy/Procedure

4	Therapeutics 01/2021 - 10/2016
2	Drug Therapy (Chemotherapy) 01/2023 - 01/2020
1	Bariatric Surgery 05/2020
1	Ketogenic Diet 09/2018