Paul Baas Selected Research

defactinib

1/2019

Maintenance Defactinib Versus Placebo After First-Line Chemotherapy in Patients With Merlin-Stratified Pleural Mesothelioma: COMMAND-A Double-Blind, Randomized, Phase II Study.

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Paul Baas Research Topics

Disease

54	Neoplasms (Cancer) 04/2024 - 02/2002
41	Malignant Mesothelioma 04/2024 - 02/2002
40	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2024 - 03/2002
40	Mesothelioma 11/2023 - 02/2002
16	Lung Neoplasms (Lung Cancer) 04/2024 - 03/2002
6	Disease Progression 11/2023 - 05/2013
6	Neutropenia 01/2021 - 07/2008
5	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2002
3	Fatigue 01/2021 - 02/2015
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2016 - 09/2009
2	Pneumonia (Pneumonitis) 01/2021 - 01/2016
2	Anemia 01/2020 - 02/2015
2	Leukopenia 01/2020 - 05/2012
2	Constipation 02/2015 - 05/2005
2	Dyspnea (Shortness of Breath) 09/2011 - 01/2002
2	Carcinogenesis 04/2008 - 05/2007
2	multiple Basal cell carcinoma 11/2006 - 02/2003
1	Chronic Obstructive Pulmonary Disease (COPD) 11/2023
1	Breast Neoplasms (Breast Cancer) 01/2023
1	Encephalitis (Encephalitis, Rasmussen) 01/2021
1	Heart Failure 01/2021
1	Asthenia 01/2021
1	Pain (Aches) 01/2021
1	Infections 01/2021
1	Cough 01/2021
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Pleural Effusion (Pleural Effusions) 02/2019
1	Drug-Related Side Effects and Adverse Reactions 01/2018

Drug/Important Bio-Agent (IBA)

15	NivolumabIBA 04/2024 - 07/2015
12	Biomarkers (Surrogate Marker)IBA 04/2024 - 02/2002
12	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 02/2002
9	pembrolizumabIBA 11/2023 - 04/2016
8	IpilimumabIBA 01/2023 - 01/2019
8	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2006 - 02/2003
7	PlatinumIBA 11/2023 - 02/2006
7	Immune Checkpoint InhibitorsIBA 01/2023 - 12/2020
7	Gemcitabine FDA Link 02/2021 - 09/2003
7	temoporfinIBA 06/2007 - 02/2003
6	Pemetrexed (MTA)FDA Link 11/2023 - 07/2008
6	AsbestosIBA 12/2022 - 11/2004
6	B7-H1 AntigenIBA 10/2021 - 10/2018
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2008
4	Docetaxel (Taxotere)FDA Link 10/2021 - 07/2015
3	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2007 - 02/2002
2	AntibodiesIBA 04/2024 - 02/2003
2	Ribosomal Protein S6IBA 12/2022 - 12/2022
2	AntigensIBA 01/2022 - 10/2018
2	antigen CYFRA21.1IBA 11/2021 - 03/2008
2	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 01/2020
2	Vinorelbine (Navelbine)FDA LinkGeneric 01/2021 - 02/2002
2	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2008
2	Tyrosine Kinase InhibitorsIBA 02/2019 - 01/2018
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 05/2013
2	Bortezomib (Velcade)FDA Link 09/2013 - 09/2012
2	Carboplatin (JM8)FDA LinkGeneric 05/2013 - 07/2008
2	Thalidomide (Thalomid)FDA Link 05/2013 - 05/2005
2	MesothelinIBA 05/2012 - 01/2008
2	Acetylcysteine (Siran)FDA LinkGeneric 09/2011 - 02/2002
2	taxaneIBA 07/2008 - 04/2004
2	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2008 - 05/2007
2	Fluticasone (Cutivate)FDA LinkGeneric 04/2008 - 05/2007
2	SmokeIBA 05/2007 - 02/2002
2	Photosensitizing Agents (Photosensitizers)IBA 07/2006 - 09/2005
1	Immune Checkpoint ProteinsIBA 04/2024
1	relatlimabIBA 04/2024
1	lenvatinibIBA 11/2023
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2023
1	Complementarity Determining Regions (Complementarity Determining Region)IBA 01/2023
1	Peptides (Polypeptides)IBA 01/2022
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022
1	LigandsIBA 10/2020
1	ElectrolytesIBA 01/2020
1	AlbuminsIBA 01/2020
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2020
1	Cell-Free Nucleic AcidsIBA 02/2019
1	defactinibIBA 01/2019
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2019
1	Neurofibromin 2 (Merlin)IBA 01/2019
1	Glycoproteins (Glycoprotein)IBA 10/2018
1	Immunoconjugates (Immunoconjugate)IBA 10/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Genetic Markers (Genetic Marker)IBA 01/2018
1	Circulating Tumor DNAIBA 01/2018
1	Phosphotransferases (Kinase)IBA 01/2017

Therapy/Procedure

34	Drug Therapy (Chemotherapy) 04/2024 - 02/2002
33	Therapeutics 04/2024 - 03/2002
18	Immunotherapy 04/2024 - 01/2016
13	Radiotherapy 01/2021 - 02/2002
8	Photochemotherapy (Photodynamic Therapy) 11/2006 - 02/2003
3	Pneumonectomy (Lung Volume Reduction) 01/2020 - 06/2015
2	Electronic Nose 11/2023 - 10/2021
2	Lasers (Laser) 10/2019 - 01/2019
2	Thoracotomy 01/2016 - 02/2002
2	Cytoreduction Surgical Procedures 10/2007 - 02/2002
2	Conformal Radiotherapy 09/2006 - 02/2003
1	Retreatment 10/2020
1	Adjuvant Chemotherapy 10/2018
1	Operative Surgical Procedures 10/2018
1	Molecular Targeted Therapy 01/2017
1	Postoperative Care 11/2016