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Richard Béliveau Selected Research

Neoplasms (Cancer)

1/2024Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing.
9/2022The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells.
4/2022The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers.
10/2021TH1902, a new docetaxel-peptide conjugate for the treatment of sortilin-positive triple-negative breast cancer.
1/2021New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells.
3/2014Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation.
2/2013MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells.
8/2012Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway.
5/2012Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration.
11/2010Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells.
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Richard Béliveau Research Topics

Disease

65Neoplasms (Cancer)
01/2024 - 01/2002
16Brain Neoplasms (Brain Tumor)
11/2010 - 01/2002
11Medulloblastoma
02/2013 - 11/2003
10Glioblastoma (Glioblastoma Multiforme)
05/2012 - 02/2006
8Glioma (Gliomas)
08/2010 - 01/2003
6Melanoma (Melanoma, Malignant)
01/2024 - 09/2003
6Neoplasm Metastasis (Metastasis)
01/2021 - 11/2004
6Inflammation (Inflammations)
02/2013 - 03/2002
5Fibrosarcoma
12/2009 - 01/2005
4Carcinoma (Carcinomatosis)
01/2021 - 05/2005
4Hypoxia (Hypoxemia)
12/2004 - 01/2003
3Triple Negative Breast Neoplasms
01/2024 - 10/2021
3Hemangioma (Angioma)
11/2010 - 11/2009
3Carcinogenesis
08/2008 - 11/2003
3Ischemia
10/2005 - 11/2004
2Ovarian Neoplasms (Ovarian Cancer)
04/2022 - 01/2021
2Acute Kidney Injury (Acute Renal Failure)
10/2005 - 03/2005
2Renal Cell Carcinoma (Grawitz Tumor)
06/2003 - 02/2003
1Endometrial Neoplasms (Endometrial Cancer)
04/2022
1Breast Neoplasms (Breast Cancer)
10/2021
1Neutropenia
10/2021
1Lymphatic Metastasis
10/2021
1Pathologic Processes
03/2014
1Bone Neoplasms (Bone Cancer)
03/2014
1Pain (Aches)
03/2014
1Chronic Pain
03/2014

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
07/2010 - 01/2002
12Matrix Metalloproteinase 14 (MT1-MMP)IBA
02/2013 - 04/2004
11Matrix Metalloproteinases (MMPs)IBA
02/2013 - 03/2002
10Peptides (Polypeptides)IBA
01/2024 - 12/2004
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2014 - 01/2002
6EnzymesIBA
06/2010 - 01/2003
6TeaIBA
09/2007 - 07/2002
6Messenger RNA (mRNA)IBA
08/2007 - 01/2003
6PlasminogenIBA
07/2007 - 09/2003
5matrigelIBA
01/2021 - 12/2004
4Docetaxel (Taxotere)FDA Link
01/2024 - 10/2021
4sortilinIBA
01/2024 - 01/2021
4PolyphenolsIBA
08/2012 - 11/2003
4Collagen Type I (Type I Collagen)IBA
06/2010 - 05/2004
4Tyrosine (L-Tyrosine)FDA Link
06/2010 - 05/2007
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2009 - 01/2003
4Caveolin 1IBA
04/2007 - 01/2002
3Biomarkers (Surrogate Marker)IBA
10/2021 - 01/2012
3Oxygen (Dioxygen)IBA
01/2021 - 01/2003
3Propranolol (Inderal)FDA LinkGeneric
11/2010 - 11/2009
3AntigensIBA
02/2009 - 08/2005
3ElementsIBA
02/2009 - 01/2004
3tigapotideIBA
07/2006 - 01/2005
3shark cartilage extractIBA
07/2004 - 04/2002
2Paclitaxel (Taxol)FDA LinkGeneric
04/2022 - 04/2007
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
02/2013 - 03/2009
2PhytochemicalsIBA
08/2012 - 11/2007
2CytokinesIBA
05/2012 - 01/2003
2QuercetinIBA
05/2012 - 04/2009
2CarcinogensIBA
01/2012 - 06/2008
2Adrenergic Agents (Adrenergic Drugs)IBA
11/2010 - 11/2009
2Hemoglobins (Hemoglobin)IBA
08/2010 - 08/2007
2LDL Receptors (LDL Receptor)IBA
07/2010 - 07/2007
2Thromboplastin (Tissue Factor)IBA
05/2010 - 07/2009
2Cell Surface ReceptorsIBA
01/2010 - 10/2009
2CollagenIBA
12/2009 - 08/2008
2sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
10/2009 - 05/2007
2LysophospholipidsIBA
10/2009 - 05/2007
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
07/2009 - 04/2009
2FibrinIBA
07/2009 - 01/2005
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
04/2009 - 04/2007
2Monoclonal AntibodiesIBA
02/2009 - 09/2003
2Metalloproteases (Metalloproteinases)IBA
08/2008 - 04/2002
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
06/2008 - 01/2003
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
04/2007 - 08/2005
2FibrinolysinFDA Link
02/2007 - 04/2006
2delphinidinIBA
01/2007 - 05/2006
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
05/2006 - 01/2002
2Amino AcidsFDA Link
04/2006 - 01/2005
2Conditioned Culture MediaIBA
02/2006 - 01/2003
2epigallocatechin gallate (epigallocatechin-3-gallate)IBA
02/2006 - 11/2003
2Tissue Inhibitor of Metalloproteinase-2IBA
10/2005 - 03/2005
2CreatinineIBA
10/2005 - 03/2005
2Complementary DNA (cDNA)IBA
09/2005 - 08/2005
2CaveolinsIBA
08/2005 - 05/2004
2Hyaluronic Acid (Hyaluronan)IBA
08/2005 - 05/2004
2TubulinIBA
11/2004 - 11/2002
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
11/2004 - 01/2003
2rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA
11/2004 - 06/2003
1Carboplatin (JM8)FDA LinkGeneric
04/2022
1Taxoids (Taxanes)IBA
04/2022
1human ERBB2 proteinIBA
10/2021
1LigandsIBA
10/2021
1Estrogen ReceptorsIBA
10/2021
1Olive OilIBA
03/2014
1AntioxidantsIBA
03/2014
1Plant Oils (Vegetable Oils)IBA
03/2014
1ANG2002IBA
03/2014
1Analgesics (Analgesic Drugs)IBA
03/2014
1Formaldehyde (Formol)FDA Link
03/2014

Therapy/Procedure

18Therapeutics
01/2021 - 01/2002
4Radiotherapy
11/2006 - 11/2003
2Drug Therapy (Chemotherapy)
05/2010 - 08/2005
1Analgesia
03/2014