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Ravi Alvala Selected Research

Neoplasms (Cancer)

4/2024Design and synthesis of novel coumarin-benzimidazole hybrids as human galectin-1 inhibitors.
1/2023Coumarin and Piperazine Conjugates as Selective Inhibitors of the Tumor-associated Carbonic Anhydrase IX and XII Isoforms.
8/2021An updated patent review of galectin-1 and galectin-3 inhibitors and their potential therapeutic applications (2016-present).
1/2021Synthesis and biological evaluation of novel 4,7-disubstituted coumarins as selective tumor-associated carbonic anhydrase IX and XII inhibitors.
1/2020Synthesis, 18F-radiolabeling and apoptosis inducing studies of novel 4, 7-disubstituted coumarins.
1/2020Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies.
1/2019Synthesis and Biological Evaluation of Novel Heterocyclic Imines Linked Coumarin- Thiazole Hybrids as Anticancer Agents.
1/2019Synthesis and biological evaluation of morpholines linked coumarin-triazole hybrids as anticancer agents.
1/2019Human Galectin-1 and Its Inhibitors: Privileged Target for Cancer and HIV.
1/2012Synthesis and in vitro antiproliferative activity of 2-methyl-3-(2-piperazin-1-yl-ethyl)-pyrido[1,2-a]pyrimidin-4-one derivatives against human cancer cell lines.

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Ravi Alvala Research Topics

Disease

10Neoplasms (Cancer)
04/2024 - 01/2012
2Neoplasm Metastasis (Metastasis)
01/2019 - 01/2019
1Fibrosis (Cirrhosis)
08/2021
1Lung Neoplasms (Lung Cancer)
01/2020
1Immune System Diseases (Immune Disorders)
01/2019
1Melanoma (Melanoma, Malignant)
01/2019
1Osteosarcoma (Osteogenic Sarcoma)
01/2019
1Diabetes Mellitus
04/2016
1Chronic Disease (Chronic Diseases)
04/2016
1Obesity
07/2013

Drug/Important Bio-Agent (IBA)

5coumarinIBA
04/2024 - 01/2019
4Galectin 1 (LGALS1)IBA
01/2020 - 01/2019
31-nitrohydroxyphenyl-N-benzoylalanine (GAL 1)IBA
04/2024 - 01/2019
3Proteins (Proteins, Gene)FDA Link
08/2021 - 07/2013
2benzimidazoleIBA
04/2024 - 01/2020
2Carbonic Anhydrase IXIBA
01/2023 - 01/2021
2Protein Isoforms (Isoforms)IBA
01/2023 - 01/2021
2CoumarinsIBA
01/2021 - 01/2020
2TriazolesIBA
01/2020 - 01/2019
2LectinsIBA
01/2019 - 01/2019
1CarbohydratesIBA
04/2024
1PiperazineIBA
01/2023
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
01/2021
15,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA
01/2020
1FITC-annexin A5IBA
01/2020
1Matrix Metalloproteinases (MMPs)IBA
01/2020
1DAPIIBA
01/2020
1Fluorine-18IBA
01/2020
1GalactosidesIBA
01/2019
1IminesIBA
01/2019
1MorpholinesIBA
01/2019
1ThiazolesIBA
01/2019
1Galectins (Galectin)IBA
01/2019
1Insulin (Novolin)FDA Link
04/2016
1Blood Glucose (Blood Sugar)IBA
04/2016
1Sirtuin 1IBA
07/2013
1ethyl acetateIBA
07/2013
1Messenger RNA (mRNA)IBA
07/2013
1thiazolyl blueIBA
01/2012

Therapy/Procedure

1Therapeutics
04/2024