Jun-Ichi Akagi Selected Research

Neoplasms (Cancer)

4/2019	Dimethylarsinic acid may promote prostate carcinogenesis in rats.
1/2019	4-Methylthio-3-butenyl isothiocyanate (MTBITC) induced apoptotic cell death and G2/M cell cycle arrest via ROS production in human esophageal epithelial cancer cells.
1/2018	4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells.
12/2015	Early Detection of Genotoxic Urinary Bladder Carcinogens by Immunohistochemistry for γ-H2AX.
5/2015	Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats.
5/2009	Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.

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Jun-Ichi Akagi Research Topics

Disease

7	Body Weight (Weight, Body) 04/2019 - 10/2016
6	Neoplasms (Cancer) 04/2019 - 05/2009
6	Carcinogenesis 04/2019 - 06/2013
3	Xeroderma Pigmentosum (Kaposi's Disease) 02/2012 - 06/2004
2	Hypertrophy 01/2018 - 05/2015
1	Chromosome Aberrations (Chromosome Abnormalities) 01/2023
1	Anemia 01/2017
1	Hyperlipidemias (Hyperlipidemia) 01/2017
1	Necrosis 01/2017
1	Obesity 01/2017
1	Cholangiocarcinoma 01/2017
1	Papilloma (Papillomatosis) 10/2016
1	Hyperplasia 12/2015
1	Genomic Instability 12/2015

Drug/Important Bio-Agent (IBA)

5	CarcinogensIBA 04/2019 - 06/2013
4	4-(methylthio)-3-butenyl isothiocyanateIBA 01/2019 - 10/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 06/2013
2	Rad30 proteinIBA 05/2009 - 06/2004
1	TitaniumIBA 01/2023
1	2-Acetylaminofluorene (2 Acetylaminofluorene)IBA 04/2019
1	ArsenicIBA 04/2019
1	Arsenicals (Arsenic Compounds)IBA 04/2019
1	Cacodylic Acid (Cacodylate)IBA 04/2019
1	HMGB2 ProteinIBA 04/2019
1	Ether (Diethyl Ether)IBA 03/2019
1	5-hexenyl isothiocyanateIBA 12/2018
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2018
1	alpha-ChlorohydrinIBA 01/2017
1	Methylene Chloride (Dichloromethane)IBA 01/2017
1	propylene dichlorideIBA 01/2017
1	nitrosobenzylmethylamineIBA 10/2016
1	UracilIBA 12/2015
1	phenethyl isothiocyanate (PEITC)IBA 12/2015
1	melamineIBA 12/2015
1	GlobulinsIBA 05/2015
1	AlbuminsIBA 05/2015
1	Serum AlbuminIBA 05/2015
1	Diethylhexyl Phthalate (DEHP)IBA 05/2015
1	DNA Repair EnzymesIBA 06/2013
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 02/2012
1	Pyrimidine DimersIBA 02/2012
1	Benzo(a)pyreneIBA 06/2004

Therapy/Procedure

2	Oral Administration 01/2023 - 01/2017