Juan Carlos Aguillón Selected Research

Rheumatoid Arthritis

8/2022	TNF-α Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2.
1/2019	Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies.
12/2014	Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients.
6/2012	Weak CD4+ T-cell responses to citrullinated vimentin in rheumatoid arthritis patients carrying HLA-DR9 alleles.
12/2011	Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-γ-producing NK cell and regulatory T cell subsets.

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Juan Carlos Aguillón Research Topics

Disease

5	Rheumatoid Arthritis 08/2022 - 12/2011
4	Neoplasms (Cancer) 11/2017 - 08/2004
3	Autoimmune Diseases (Autoimmune Disease) 08/2022 - 11/2016
2	Melanoma (Melanoma, Malignant) 01/2006 - 08/2004
1	Adenocarcinoma 11/2017
1	Stomach Neoplasms (Stomach Cancer) 03/2016
1	Hypersensitivity (Allergy) 01/2014
1	Latex Hypersensitivity (Latex Allergy) 01/2014
1	Chronic Periodontitis 10/2011

Drug/Important Bio-Agent (IBA)

3	CytokinesIBA 08/2022 - 08/2004
3	Interleukin-10 (Interleukin 10)IBA 10/2011 - 08/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2022 - 12/2014
2	micaIBA 11/2017 - 03/2016
2	AntigensIBA 11/2016 - 06/2012
2	Proteins (Proteins, Gene)FDA Link 03/2016 - 01/2014
2	alanyl- tyrosyl- methionyl- threonyl- methionyl- lysyl- isoleucyl- arginyl- asparagineIBA 10/2011 - 08/2004
2	Peptides (Polypeptides)IBA 10/2011 - 08/2004
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 11/2017
1	Transcription Factors (Transcription Factor)IBA 11/2017
1	Metalloproteases (Metalloproteinases)IBA 11/2017
1	LigandsIBA 03/2016
1	Messenger RNA (mRNA)IBA 03/2016
1	Biomarkers (Surrogate Marker)IBA 12/2014
1	Immunoglobulin E (IgE)IBA 01/2014
1	Rubber (Elastica)IBA 01/2014
1	AllergensIBA 01/2014
1	LatexIBA 01/2014
1	HLA-DR9 antigenIBA 06/2012
1	Anti-Citrullinated Protein AntibodiesIBA 06/2012
1	VimentinIBA 06/2012
1	interleukin-21 (interleukin 21)IBA 10/2011

Therapy/Procedure

3	Therapeutics 01/2019 - 08/2004
1	Drug Therapy (Chemotherapy) 01/2006