Abstract | RATIONALE: The pathology of gouty arthritis and reactive arthritis (ReA) partially overlaps, and both diseases are characterized by the production of inflammatory cytokines associated with the activation of monocytes and macrophages. However, the precise cytokine profile of cases with a coexistence of both diseases is unknown, and there are few reports on the course of treatment in patients with both gouty arthritis and ReA. PATIENT CONCERNS: DIAGNOSES: He was diagnosed with HLA-B27 associated Chlamydia-induced ReA accompanied by gout flares. INTERVENTIONS: OUTCOMES: After starting ADA, the patient's symptoms and laboratory findings showed rapid improvement and he achieved clinical remission 1 month after initiation of ADA treatment. As of this writing, the patient's clinical remission has been maintained for >1 year. LESSONS:
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Authors | Remi Sumiyoshi, Tomohiro Koga, Sosuke Tsuji, Yushiro Endo, Ayuko Takatani, Toshimasa Shimizu, Takashi Igawa, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Atsushi Kawakami |
Journal | Medicine
(Medicine (Baltimore))
Vol. 98
Issue 40
Pg. e17233
(Oct 2019)
ISSN: 1536-5964 [Electronic] United States |
PMID | 31577714
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Cytokines
- Inflammation Mediators
- PHB2 protein, human
- Prohibitins
- Tumor Necrosis Factor-alpha
- C-Reactive Protein
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Topics |
- Adult
- Arthritis, Reactive
(drug therapy, etiology)
- C-Reactive Protein
(analysis)
- Chlamydia Infections
(complications, drug therapy)
- Chlamydia trachomatis
- Cytokines
(metabolism)
- Gout
(complications, drug therapy)
- Humans
- Inflammation Mediators
(metabolism)
- Male
- Prohibitins
- Tumor Necrosis Factor-alpha
(antagonists & inhibitors)
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