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Prednisolone (Predate)

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
Also Known As:
Predate; Di-Adreson-F; Predonine; Di Adreson F; DiAdresonF; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-
Networked: 12013 relevant articles (1744 outcomes, 1312 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Kawakami, Atsushi: 21 articles (04/2022 - 01/2004)
2. Kohno, Shigeru: 20 articles (01/2014 - 07/2002)
3. Nitta, Kosaku: 18 articles (10/2021 - 01/2002)
4. Tsurumi, Hisashi: 18 articles (01/2020 - 06/2002)
5. Moriwaki, Hisataka: 17 articles (12/2017 - 01/2002)
6. Origuchi, Tomoki: 15 articles (03/2020 - 01/2004)
7. Pieters, Rob: 15 articles (11/2019 - 08/2004)
8. Hara, Takeshi: 15 articles (10/2018 - 06/2002)
9. Nakamura, Hideki: 14 articles (04/2022 - 01/2006)
10. Matsuda, Masayuki: 14 articles (02/2022 - 05/2002)

Related Diseases

1. Nephrotic Syndrome (Syndrome, Nephrotic)
2. Proteinuria
3. Asthma (Bronchial Asthma)
08/01/2022 - "LGG may reduce the dosage of prednisolone and thus may be beneficial in the treatment of asthma."
02/01/2019 - "From baseline to month 24: mean change in forced expiratory volume in 1 s (FEV1) was 137 ml and the daily dose of OCS decreased (11.6 mg to 6.4 mg prednisolone equivalent); the percentage of patients with no severe clinically significant exacerbations increased (29.5% to 95.1%); Asthma Control Test scores improved (12.4 to 17.3) and mean total number of days of asthma-related medical healthcare use decreased (6.8 days to 0.4 days). "
01/01/2017 - "There was a 76.7% reduction in daily mean maintenance OCS dose (prednisolone equivalent) from 25.8 mg (n = 43) to 6.0 mg (p < 0.0001), associated with clinically significant improvement in asthma control questionnaire (ACQ) from mean score of 4.1 (range 3.7-4.7) to 2.27 (range 0.5-4.1) p < 0.0001. "
12/01/2003 - "There was a significant improvement after oral prednisolone compared with placebo in FEV1, ml (mean difference, 237; 95% confidence intervals, 43, 231; p = 0.019), morning PEF L/m (mean difference, 36.8; 95% confidence intervals (CI), 11, 62; p = 0.006), and asthma control score (mean difference, -0.72; 95% CI, -1.2, -0.3; p = 0.004) in never-smokers with asthma but no change in smokers with asthma (mean differences of 47, 6.5, and -0.05 with p values of 0.605, 0.47, and 0.865, respectively). "
09/15/2008 - "To determine whether a 5-day course of oral prednisolone is superior to a 3-day course in reducing the 2-week morbidity of children with asthma exacerbations who are not hospitalised. "
4. Inflammation (Inflammations)
5. Fever (Fevers)

Related Drugs and Biologics

1. Cyclophosphamide (Cytoxan)
2. Vincristine (Oncovin)
3. Doxorubicin (Adriamycin)
4. Steroids
5. Cyclosporine (Ciclosporin)
6. Methylprednisolone
7. Adrenal Cortex Hormones (Corticosteroids)
8. Rituximab (Mabthera)
9. Azathioprine (Imuran)
10. Dexamethasone (Maxidex)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Aftercare (After-Treatment)
4. Oral Administration
5. Combination Drug Therapy (Combination Chemotherapy)