Abstract | BACKGROUND: OBJECTIVES: SETTING: University of Heidelberg, Germany. METHODS: A systematic literature search was performed in December 2018 using the MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials databases without language restrictions or time limit. Studies reporting exact data on change in urinary albumin- creatinine ratio (uACR) or albuminuria as well as change in body mass index in patients with T2D undergoing metabolic surgery were included. Out of 2145 potentially eligible hits, 15 studies were included. Study quality was assessed using the Downs and Black score. Data were pooled using a random-effects model, and a Spearman's rank correlation was performed. RESULTS: No correlation was found between improved renal injury (change in uACR or albuminuria) and weight loss (change in body mass index) (rs = -.306, P = 0.504, and rs = -.086, P = .872), and no significant correlation was found between improved renal injury (change in uACR or albuminuria) and improved glycemic control (change in A1C) (rs = .378, P = .403, and rs = .500, P = .391. CONCLUSION:
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Authors | Katharina M Scheurlen, Pascal Probst, Stefan Kopf, Peter P Nawroth, Adrian T Billeter, Beat P Müller-Stich |
Journal | Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
(Surg Obes Relat Dis)
Vol. 15
Issue 6
Pg. 1006-1020
(06 2019)
ISSN: 1878-7533 [Electronic] United States |
PMID | 31104957
(Publication Type: Journal Article, Meta-Analysis, Systematic Review)
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Copyright | Copyright © 2019 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Bariatric Surgery
(statistics & numerical data)
- Diabetes Mellitus, Type 2
(complications)
- Diabetic Nephropathies
(complications, physiopathology)
- Female
- Humans
- Male
- Middle Aged
- Obesity, Morbid
(complications, surgery)
- Weight Loss
(physiology)
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