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Type 2 Diabetes Mellitus (MODY)

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Also Known As:
MODY; Noninsulin Dependent Diabetes Mellitus; Diabetes Mellitus, Type II; NIDDM; Diabetes Mellitus, Type 2; Diabetes Mellitus, Non Insulin Dependent; Diabetes Mellitus, Noninsulin Dependent; Diabetes Mellitus, Noninsulin-Dependent; Maturity-Onset Diabetes; Noninsulin-Dependent Diabetes Mellitus; Type 2 Diabetes; Adult-Onset Diabetes Mellitus; Diabetes Mellitus, Adult Onset; Diabetes Mellitus, Ketosis Resistant; Diabetes Mellitus, Maturity Onset; Diabetes Mellitus, Slow Onset; Diabetes, Maturity-Onset; Diabetes, Type 2; Ketosis-Resistant Diabetes Mellitus; Maturity Onset Diabetes; Maturity Onset Diabetes Mellitus; Non-Insulin-Dependent Diabetes Mellitus; Slow-Onset Diabetes Mellitus; Stable Diabetes Mellitus; Diabetes Mellitus, Adult-Onset; Diabetes Mellitus, Ketosis-Resistant; Diabetes Mellitus, Maturity-Onset; Diabetes Mellitus, Non-Insulin-Dependent; Diabetes Mellitus, Slow-Onset; Diabetes Mellitus, Stable; Maturity-Onset Diabetes Mellitus
Networked: 95492 relevant articles (6741 outcomes, 22158 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Obesity
2. Insulin Resistance
3. Weight Loss (Weight Reduction)
4. Type 2 Diabetes Mellitus (MODY)
5. Hyperglycemia

Experts

1. Hu, Frank B: 217 articles (02/2022 - 03/2002)
2. Holst, Jens J: 209 articles (10/2022 - 01/2002)
3. Zinman, Bernard: 208 articles (10/2022 - 08/2001)
4. Rosenstock, Julio: 185 articles (01/2022 - 04/2002)
5. Khunti, Kamlesh: 172 articles (11/2022 - 03/2008)
6. Ji, Linong: 170 articles (06/2022 - 11/2002)
7. Buse, John B: 159 articles (11/2022 - 07/2002)
8. Vilsbøll, Tina: 159 articles (10/2022 - 09/2003)
9. Jia, Weiping: 157 articles (08/2021 - 05/2002)
10. Leiter, Lawrence A: 153 articles (12/2022 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Type 2 Diabetes Mellitus:
1. Insulin (Novolin)FDA Link
2. Glucose (Dextrose)FDA LinkGeneric
3. Metformin (Glucophage)FDA LinkGeneric
4. Hypoglycemic Agents (Hypoglycemics)IBA
5. Blood Glucose (Blood Sugar)IBA
10/17/2010 - "Early detection of blood glucose abnormalities is essential to improve long term prognosis of type 2 diabetes, as intervention strategies could be the most effective in youngsters. "
07/01/2015 - "Dorsolateral frontal lobe is associated with aspects of cognition especially right frontal lobe is involved in episodic memory retrieval, ninety percent of the diabetic cases are type 2 in nature globally and yoga is very effective in stabilizing the brain metabolites by bringing the blood glucose levels to near or within the physiological range in type 2 diabetes. "
01/01/2009 - "Executive Summary Table 1:Meta-Analyses of Reduction in HbA(1c) Values for Analyzed StudiesGroupEstimate of effect(95% Confidence Interval)Statistical Heterogeneity (I(2))FOLLOW-UP values     All studies-0.48 [-0.70 to -0.26]45%     Upload studies-0.39 [-0.66 to -0.13]48%     Web entry studies-0.66 [-0.99 to -0.33]0%Change-from-baseline values (p=0.5)     All studies-0.50 [-0.80 to -0.19]65%     Upload studies-0.26 [-0.55 to 0.02]45%     Web entry studies-0.78 [-1.14 to -0.43]0%Change-from-baseline values (p=0.65)     All studies-0.52 [-0.82 to -0.21]73%     Upload studies-0.25 [-0.51 to 0.01]46%     Web entry studies-0.78 [-1.08 to -0.48]0%Change-from-baseline values (p=0.85)     All studies-0.54 [-0.84 to -0.24]85%     Upload studies-0.21 [-0.41 to 0.00]47%     Web entry studies-0.81 [-1.11 to -0.51]49% Based on low quality evidence, blood glucose home telemonitoring technologies confer a statistically significant reduction in HbA1c of ~0.50% in comparison to usual care when used adjunctively to a broader telemedicine initiative for adults with type 2 diabetes.Exploratory"
01/01/2009 - "Meta-analysis of the seven trials identified a moderate but significant reduction in HbA1c levels (~0.5% reduction) in favour blood glucose home telemonitoring compared to usual care for adults with type 2 diabetes). "
11/01/2022 - "It was hypothesized that muscle mass could have a significant influence on blood glucose level and this corelation if established successfully could pave way for novel treatment modalities for type 2 diabetes mellitus (T2DM). "
6. LipidsIBA
7. Glucagon-Like Peptide 1 (GLP 1)IBA
8. Sitagliptin Phosphate (Januvia)FDA Link
9. LiraglutideFDA Link
10. Pioglitazone (Actos)FDA Link

Therapies and Procedures

1. Therapeutics
2. Glycemic Control
3. Bariatric Surgery
4. Gastric Bypass (Roux-en-Y Gastric Bypass)
5. Gastrectomy