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Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

Abstract
The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the prior position statements, published in 2012 and 2015, on the management of type 2 diabetes in adults. A systematic evaluation of the literature since 2014 informed new recommendations. These include additional focus on lifestyle management and diabetes self-management education and support. For those with obesity, efforts targeting weight loss, including lifestyle, medication and surgical interventions, are recommended. With regards to medication management, for patients with clinical cardiovascular disease, a sodium-glucose cotransporter-2 (SGLT2) inhibitor or a glucagon-like peptide-1 (GLP-1) receptor agonist with proven cardiovascular benefit is recommended. For patients with chronic kidney disease or clinical heart failure and atherosclerotic cardiovascular disease, an SGLT2 inhibitor with proven benefit is recommended. GLP-1 receptor agonists are generally recommended as the first injectable medication.
AuthorsMelanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
JournalDiabetologia (Diabetologia) Vol. 61 Issue 12 Pg. 2461-2498 (12 2018) ISSN: 1432-0428 [Electronic] Germany
PMID30288571 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Glucagon-Like Peptide-1 Receptor
  • Hypoglycemic Agents
  • Insulin
  • Sodium-Glucose Transporter 2 Inhibitors
  • Liraglutide
Topics
  • Cardiovascular Diseases (drug therapy)
  • Consensus
  • Diabetes Mellitus, Type 2 (drug therapy)
  • Europe
  • Glucagon-Like Peptide-1 Receptor (agonists)
  • Heart Failure (drug therapy)
  • Humans
  • Hyperglycemia (drug therapy)
  • Hypoglycemic Agents (therapeutic use)
  • Insulin (therapeutic use)
  • Liraglutide (therapeutic use)
  • Renal Insufficiency, Chronic (drug therapy)
  • Sodium-Glucose Transporter 2 Inhibitors (therapeutic use)
  • United States

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