Chronic Renal Insufficiency

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1912 relevant articles (58 outcomes, 158 trials/studies) found for this Disease

Description: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Also Known As:

Renal Insufficiency, Chronic; Chronic Kidney Insufficiency; Chronic Kidney Insufficiencies; Chronic Renal Insufficiencies; Kidney Insufficiencies, Chronic; Renal Insufficiencies, Chronic; Kidney Insufficiency, Chronic

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Insufficiency: 5313

Chronic Renal Insufficiency: 1912

Chronic Kidney Failure: 20156

Female Urogenital Diseases and Pregnancy Complications

Female Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Insufficiency: 5313

Chronic Renal Insufficiency: 1912

Chronic Kidney Failure: 20156

Related Diseases

1.	Chronic Kidney Failure (Chronic Renal Failure)
2.	Hypertension (High Blood Pressure)
3.	Anemia
4.	Infection
5.	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)

Experts

1.	Tonelli, Marcello: 5 articles (11/2004 - 08/2002)
2.	Curhan, Gary C: 4 articles (11/2004 - 11/2002)
3.	Waksman, Ron: 3 articles (03/2006 - 01/2002)
4.	Pichard, Augusto D: 3 articles (03/2006 - 01/2002)
5.	Satler, Lowell F: 3 articles (03/2006 - 01/2002)
6.	Kent, Kenneth M: 3 articles (03/2006 - 01/2002)
7.	Canaud, B: 2 articles (05/2008 - 01/2002)
8.	Zhang, Xun: 2 articles (06/2007 - 01/2006)
9.	Liang, Min: 2 articles (06/2007 - 01/2006)
10.	Jiang, Jian Ping: 2 articles (06/2007 - 01/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chronic Renal Insufficiency:

1.	CreatinineIBA 05/01/1987 - "Chronic renal insufficiency, defined as a creatinine clearance of less than 0.8 ml/second/1.73 m2 for more than 12 months, was similar in adults (40 percent) and children (34 percent). " 03/01/2008 - "METHODS: We conducted a prospective, randomized, double-blind, placebo-controlled, 2-center trial, involving 247 consecutive patients with chronic renal insufficiency (calculated creatinine clearance < or = 60 mL/min and/or serum creatinine > or = 1.1 mg/dL) undergoing coronary angiography. " 01/01/1999 - "BP and creatinine clearance were normal at the end of the trial in all but one group 2 patient, who developed chronic renal insufficiency. " 11/01/1997 - "After excluding patients who were not examined at follow-up or who poorly complied during the study period, the opened randomized study consisted of 42 patients with chronic renal insufficiency (creatinine clearance <60 mL/min and >10 mL/min). " 07/01/2009 - "However, the exact correlation between various levels of creatinine elevation relative to the baseline and subsequent mortality in patients with chronic renal insufficiency (CRI) is not well established. " Order ALL the reference details at left...
2.	Furosemide (Lasix)FDA LinkGeneric 06/01/2008 - "AIM: To compare natriuretic, kaliuretic, diuretic and free water clearance efficacy of continuous versus bolus intravenous furosemide administration in patients with chronic renal insufficiency. " 06/01/2008 - "MATERIAL AND METHODS: In a prospective randomized cross-over trial, 42 patients of chronic renal insufficiency were randomized to receive the same dose of intravenous furosemide as bolus and continuous infusion. " 08/01/1986 - "Response to furosemide in chronic renal insufficiency: rationale for limited doses." 06/01/1984 - "Thus also in the chronic renal insufficiency there is the indication of the furosemide therapy only then, when the extracellular space or the intravasal volume are enlarged. " 06/01/1984 - "[Furosemide effects in patients with chronic renal insufficiency]" Order ALL the reference details at left...
3.	benazepril (Briem)FDA LinkGeneric 09/01/2006 - "Evaluation of the clinical efficacy of benazepril in the treatment of chronic renal insufficiency in cats." 01/01/2002 - "PATIENTS AND INTERVENTIONS: In the clinical studies on which this economic analysis was based, patients with chronic renal insufficiency of various aetiologies were randomised to antihypertensive therapy with or without concomitant benazepril. " 12/01/1997 - "A prospective, randomized, double-blind trial recently demonstrated that treating patients with chronic renal insufficiency with benazepril significantly decelerates the rate of progression of the disease. " 04/06/2006 - "Benazepril for advanced chronic renal insufficiency." 04/06/2006 - "Benazepril for advanced chronic renal insufficiency." Order ALL the reference details at left...
4.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 06/01/1997 - "This study was undertaken to compare the effects of chronic angiotensin-converting enzyme (ACE) inhibition on blood pressure (BP) and renal hemodynamics in older black and nonblack hypertensive patients with chronic renal insufficiency. " 09/01/2002 - "Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency." 12/01/2001 - "Blood pressure and angiotensin converting enzyme inhibitor use in hypertensive patients with chronic renal insufficiency." 08/01/2000 - "Risk factors for moderate chronic renal insufficiency were identified using a proportional hazards model controlling for age, sex, race, systolic blood pressure, and angiotensin-converting enzyme (ACE) inhibitor use. " 01/01/1987 - "[Serum angiotensin converting enzyme activity in patients with chronic renal insufficiency]" Order ALL the reference details at left...
5.	CalciumIBA 11/01/1975 - "[Study of calcium metabolism by Ca47 during chronic renal insufficiency]" 01/01/1968 - "Studies of calcium metabolism in chronic renal insufficiency." 10/01/2005 - "Thus, chronic renal insufficiency in the absence of dialysis is not associated with increased reference segment or lesion site plaque burden and calcium. " 05/01/2002 - "Management of disturbances of calcium and phosphate metabolism in chronic renal insufficiency, with emphasis on the control of hyperphosphataemia." 06/01/1998 - "[Anomalies of phosphate and calcium metabolism in chronic renal insufficiency]" Order ALL the reference details at left...
6.	ErythropoietinIBA 02/01/1994 - "The study shows that subcutaneous recombinant human erythropoietin is both effective and safe in anaemic children and adolescents with chronic renal insufficiency." 03/01/2007 - "Erythropoietin (EPO) production is diminished in patients suffering from chronic renal insufficiency or acute rejection. " 02/01/2003 - "A 75-year-old woman with chronic renal insufficiency was treated with subcutaneous erythropoietin. " 02/01/2003 - "Erythropoietin-induced hypertensive urgency in a patient with chronic renal insufficiency: case report and review of the literature." 08/01/1996 - "Usefulness and risk of erythropoietin therapy in pregnancies of patients with chronic renal insufficiency." Order ALL the reference details at left...
7.	Acetylcysteine (Siran)FDA LinkGeneric 03/01/2003 - "In patients with chronic renal insufficiency, acetylcysteine in a dose of 600 mg twice a day before and after cardiac catheterization, along with intravenous fluids, is as effective as fluids alone in the prevention of CIN when moderate to high doses of contrast are used." 08/23/2003 - "We aimed to assess the efficacy of acetylcysteine to prevent contrast nephropathy after administration of radiocontrast media in patients with chronic renal insufficiency. " 08/23/2003 - "METHODS: We did a meta-analysis of randomised controlled trials comparing acetylcysteine and hydration with hydration alone for preventing contrast nephropathy in patients with chronic renal insufficiency. " 06/01/2006 - "Hydratation associated with acetylcysteine seems to be able to prevent contrast induced nephropathy in patients with risk factors for chronic renal insufficiency. " 12/01/2004 - "Compared with periprocedural hydration alone, acetylcysteine with hydration significantly reduces the risk of contrast nephropathy in patients with chronic renal insufficiency by 50%. " Order ALL the reference details at left...
8.	Sirolimus (Rapamycin)FDA Link 12/01/2003 - "METHODS: We performed a retrospective review of the medical records of OLT recipients suffering from chronic renal insufficiency and treated with sirolimus at the University of Miami. " 02/01/2003 - "In liver transplant recipients with chronic renal insufficiency, conversion to sirolimus-based immunosuppression allows complete withdrawal of CIs, leading to some improvement in renal function." 03/15/2006 - "Impact of chronic renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary intervention with sirolimus-eluting stents versus bare metal stents." 05/01/2008 - "The purpose of this study is to review the clinical experience with sirolimus immunosuppression in liver transplant patients with calcineurin inhibitor-induced chronic renal insufficiency. " 06/01/2008 - "Sirolimus-based immunosuppressive therapy in liver transplant recipient with tacrolimus-related chronic renal insufficiency." Order ALL the reference details at left...
9.	Mannitol (Osmitrol)FDA LinkGeneric 11/01/1981 - "We conclude that administration of hypertonic mannitol 60 minutes after administration of the radiographic contrast material is highly effective in preventing ARF after infusion IVP in patients with chronic renal insufficiency." 11/01/1981 - "Effect of hypertonic mannitol in patients with chronic renal insufficiency." 01/01/1969 - "Mannitol infusion in regular haemodialysis treatment for chronic renal insufficiency." 11/01/1966 - "[Therapeutic possibilities of the use of mannitol in chronic renal insufficiency]" 08/21/1965 - "[The influencing of kidney function with mannitol infusions in acute and chronic renal insufficiency]" Order ALL the reference details at left...
10.	Enalapril FDA LinkGeneric 09/27/1985 - "The efficacy of antihypertensive therapy with enalapril was evaluated in this animal model of chronic renal insufficiency. " 03/01/2002 - "[Effect of enalapril on progression of chronic renal insufficiency caused by diabetes and other etiologies: a 2-year study]" 04/01/1990 - "In conclusion this study shows antihypertensive therapy with enalapril during chronic renal insufficiency to be effective at low dosage (5-10 mg) in lowering blood pressure and to have a good safety profile." 02/01/2003 - "CONCLUSIONS: In moderate to severe chronic renal insufficiency the same degree of blood pressure control was achieved on low as well as moderate daily doses of enalapril. " 06/01/1989 - "Efficacy and renal effects of enalapril therapy for hypertensive patients with chronic renal insufficiency." Order ALL the reference details at left...

Therapies and Procedures

1.	Renal Dialysis (Hemodialysis) 08/01/2001 - "This study investigates genomic damage in peripheral lymphocytes from patients with moderate to severe chronic renal insufficiency and those on long-term maintenance hemodialysis (MHD) and hemodiafiltration therapy. " 07/01/1988 - "[Study of the thyroid function in patients with chronic renal insufficiency in hemodialysis]" 02/01/1987 - "The task of the study was to investigate the effect of systematic hemodialysis on lipid and hormonal metabolic indices in patients with chronic renal insufficiency (CRI). " 03/01/1985 - "[Echocardiographic studies in children with chronic kidney insufficiency and intermittent hemodialysis treatment]" 12/01/1976 - "[Electrolyte studies on erythrocytes in chronic renal insufficiency prior to and following hemodialysis using diclysates with varying electrolyte concentration]" Order ALL the reference details at left...
2.	Transplants (Transplant) 07/01/1995 - "With improved graft and patient survival, the incidence of chronic renal insufficiency has increased. " 08/01/2007 - "We queried the chronic renal insufficiency (CRI), dialysis, and transplant registries of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) to characterize the frequency of rhGH utilization, factors related to its usage, and the relationship between rhGH usage and catch-up growth. " 07/01/2000 - "Utilizing the chronological age of 18 years as the arbitrary age of final adult height for children with chronic renal insufficiency, all patients enrolled in the North American Pediatric Renal Transplant Cooperative Study prior to January 1999, and who had at least one follow-up visit at age 18 years or older, were evaluated. " 05/01/1998 - "The 1996 annual report of the Chronic Renal Insufficiency Arm of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) summarizes descriptive data and highlights important features on 1,725 patients from 130 centers. " 06/01/2008 - "[Can the renal transplant patient be really considered as a patient with chronic renal insufficiency?]" Order ALL the reference details at left...
3.	Protein-Restricted Diet (Diet, Protein Restricted) 06/01/2006 - "In three years prospective double-blind randomised multicentre study we monitored 66 patients with advanced chronic renal insufficiency, GFR 24.4-37.3 ml/min (0.41 to 0.62 ml/s) and BMI > or = 30 kg/m2 on long term low-protein diet (0.6 P/kg BW/day) and ACEI + ARB. " 07/01/1993 - "The effect of a low protein diet (LPD) on the progression of chronic renal insufficiency (CRI) was investigated by reviewing the published studies. " 01/01/1993 - "The effect of a low-protein diet (LPD) on chronic renal insufficiency (CRI) progression was investigated by reviewing the published studies. " 01/01/1993 - "Controlled trials on low-protein diet: effects on chronic renal insufficiency progression." 09/01/1972 - "[Study of the chemical composition of low-protein diets for patients with chronic renal insufficiency]" Order ALL the reference details at left...
4.	Transplantation (Transplant Recipients) 10/27/2008 - "The purpose of this study was to determine incidence, determinants, and progression of long-term chronic renal insufficiency (CRI) in a single-center series of pediatric liver transplant recipients. " 11/01/1999 - "STUDY AIM: The aim of this study was to report the results of 50 transplantations of kidney and pancreas performed in the same surgical centre for chronic renal insufficiency of patients with insulino-dependent diabetes. " 08/05/2002 - "OBJECTIVE: To investigate whether late referral to a nephrologist of patients with chronic renal insufficiency influences the likelihood of both transplantation and mortality among those who survive at least one year on dialysis. " 05/01/2002 - "This is most likely for patients with chronic renal insufficiency and for kidney transplant recipients. " 08/01/2000 - "The authors favor using the term chronic renal insufficiency to describe states of reduced GFR not severe enough to require dialysis or transplantation. " Order ALL the reference details at left...
5.	Nephrectomy 04/01/2009 - "Secondary to mild, chronic renal insufficiency, a staged approach was planned: EVAR followed by nephrectomy. " 02/01/2008 - "Rapid communication: chronic renal insufficiency after laparoscopic partial nephrectomy and radical nephrectomy for pathologic t1a lesions." 06/01/2002 - "OBJECTIVES: To compare the incidence of newly developed chronic renal insufficiency after partial nephrectomy (PN) and radical nephrectomy (RN). " 06/01/2002 - "Natural history of chronic renal insufficiency after partial and radical nephrectomy." 06/01/1997 - "Parathyroid gland CgA expression also was examined in rats with mild chronic renal insufficiency, induced by a 5/6 nephrectomy 5 weeks earlier. " Order ALL the reference details at left...

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