Effects of 12 weeks of combined training without caloric restriction on inflammatory markers in overweight girls.

Abstract

The objective of the present study was to investigate the effects of combined training without caloric restriction on inflammatory markers in overweight girls. Thirty-three girls (13-17 years) were assigned into overweight training (n = 17) or overweight control (n = 16) groups. Additionally, a normal-weight group (n = 15) was used as control for the baseline values. The combined training programme consisted of six resistance exercises (three sets of 6-10 repetitions at 60-70% 1 RM) followed by 30 min of aerobic exercise (walking/running) at 50-80% VO2peak, performed in the same 60 min session, 3 days/weeks, for 12 weeks. Body composition, dietary intake, aerobic fitness (VO2peak), muscular strength (1 RM), glycaemia, insulinemia, lipid profile and inflammatory markers (C-reactive protein, interleukin-6, tumour necrosis factor-alpha, interleukin-10, leptin, resistin and adiponectin) were measured before and after intervention. There was a significant decrease in body fat (P < 0.01) and increase in fat-free mass (P < 0.01), VO2peak (P < 0.01), 1 RM for leg press (P < 0.01) and bench press (P < 0.01) in the overweight training group. Concomitantly, this group presented significant decreases in serum concentrations of C-reactive protein (P < 0.05) and leptin (P < 0.05), as well as in insulin resistance (P < 0.05) after the experimental period. In conclusion, 12 weeks of combined training without caloric restriction reduced inflammatory markers associated with obesity in overweight girls.

• Authors: Wendell Arthur Lopes, Neiva Leite, Larissa Rosa da Silva, Diego Trevisan Brunelli, Arthur Fernandes Gáspari, Rosana Bento Radominski, Mara Patrícia Traina Chacon-Mikahil, Cláudia Regina Cavaglieri
• Journal: Journal of sports sciences (J Sports Sci) Vol. 34 Issue 20 Pg. 1902-12 (Oct 2016) ISSN: 1466-447X [Electronic] England
• PMID: 26852885 (Publication Type: Controlled Clinical Trial, Journal Article)

Chemical References

• Adipokines
• Biomarkers
• Cytokines
• Inflammation Mediators
• Leptin
• C-Reactive Protein

Topics

• Adipokines (blood)
• Adipose Tissue (metabolism)
• Adolescent
• Biomarkers
• Body Composition
• Body Fluid Compartments (metabolism)
• C-Reactive Protein (metabolism)
• Caloric Restriction
• Cytokines (blood)
• Exercise (physiology)
• Female
• Humans
• Inflammation (prevention & control)
• Inflammation Mediators (blood)
• Insulin Resistance
• Leptin (blood)
• Muscle Strength
• Obesity (complications, metabolism, therapy)
• Overweight
• Oxygen Consumption
• Resistance Training