Abstract |
An 88-year-old woman, with a history of resection of stage IIA lung cancer in 1998, was referred to our hospital in August 2010 complaining of upper abdominal pain, vomiting, and dark brown stools. After endoscopic examination, she was admitted with a diagnosis of Mallory-Weiss syndrome. Vomiting occurred when food intake was resumed after fasting. Intestinal obstruction was suspected on abdominal radiography, and complete small bowel obstruction was confirmed by contrast-enhanced imaging after placement of an ileus tube. A small intestinal tumor with intussusception was detected by computed tomography. At laparotomy, there was no ascites. Intussusception was found due to an ileal tumor located approximately 50 cm from the ileocecal valve, and we performed partial small bowel resection. The resected small intestine contained a submucosal tumor approximately 40 mm in diameter that had penetrated the bowel wall to reach the serosa. Pathological examination revealed a submucosal tumor that showed poor continuity with the surrounding mucosa, while the histology was squamous cell carcinoma. Immunohistochemistry showed that the tumor was CK7 positive, CK20 negative, TTF-1 negative, and CK10 positive. Based on these findings, we made a diagnosis of small intestinal metastasis at 12 years after radical resection of squamous cell carcinoma of the lung.
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Authors | Tomoki Nakamura, Osamu Chino, Takayuki Tajima, Yoichi Tanaka, Daiki Yokoyama, Tomoko Hanashi, Sotaro Sadahiro, Hiroyasu Makuuchi |
Journal | The Tokai journal of experimental and clinical medicine
(Tokai J Exp Clin Med)
Vol. 40
Issue 4
Pg. 137-40
(Dec 20 2015)
ISSN: 2185-2243 [Electronic] Japan |
PMID | 26662663
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Aged, 80 and over
- Biomarkers, Tumor
(analysis)
- Carcinoma, Squamous Cell
(diagnosis, pathology, secondary, surgery)
- Diagnostic Imaging
- Digestive System Surgical Procedures
(methods)
- Female
- Humans
- Ileal Diseases
(diagnosis, etiology, pathology, surgery)
- Ileal Neoplasms
(diagnosis, pathology, secondary, surgery)
- Intestine, Small
(surgery)
- Intussusception
(diagnosis, etiology, pathology, surgery)
- Lung Neoplasms
(pathology)
- Time Factors
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