Abdominal Pain (Pain, Abdominal)

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4396 relevant articles (249 outcomes, 244 trials/studies) found for this Disease

Description: Sensation of discomfort, distress, or agony in the abdominal region; generally associated with functional disorders, tissue injuries, or diseases.

Also Known As:

Pain, Abdominal; Abdominal Pains; Pains, Abdominal

Relationship Network

Disease Context: Research Results

Signs and Symptoms Pathological Conditions

Digestive Signs and Symptoms

Abdominal Pain: 4396

Colic: 1682

Acute Abdomen: 531

Related Diseases

1.	Diarrhea
2.	Nausea
3.	Fever (Fevers)
4.	Constipation
5.	Vomiting

Experts

1.	Goldman, Ran D: 2 articles (01/2008 - 01/2006)
2.	Ball, Thomas M: 2 articles (01/2006 - 07/2003)
3.	Monheim, Cynthia J: 2 articles (01/2006 - 07/2003)
4.	Weydert, Joy A: 2 articles (01/2006 - 07/2003)
5.	Shapiro, Daniel E: 2 articles (01/2006 - 07/2003)
6.	Bardhan, K D: 2 articles (07/2004 - 10/2001)
7.	Kim, Michael K: 2 articles (11/2003 - 04/2002)
8.	Hennes, Halim M: 2 articles (11/2003 - 04/2002)
9.	Sato, Thomas T: 2 articles (11/2003 - 04/2002)
10.	Harrison, M: 2 articles (09/2000 - 03/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Abdominal Pain:

1.	tegaserod (Zelnorm)FDA Link 01/01/2004 - "Tegaserod did not significantly improve the patients' individual symptoms of abdominal pain and discomfort although bowel habit showed a statistically significant improvement with tegaserod 4 mg and there was a non-significant trend in favour of tegaserod 12 mg. When GI symptoms were assessed separately, those indicative of GI motility such as number of bowel movements and days without bowel movements were generally improved with tegaserod although the proportion of patients experiencing diarrhoea was significantly higher in the tegaserod 12 mg group compared with placebo (RR 2.75, 95% CI 1.90, 3.97), with a number needed to harm (NNH) of 20. " 11/01/2004 - "Patients who were treated with tegaserod had an overall improvement in IBS symptoms (Subject's Assessment of Global Relief) as well as in secondary end points, such as abdominal pain and discomfort, stool consistency, change in bowel movements and relief of bloating. " 01/01/2004 - "Tegaserod has been assessed in a number of international multicentre trials and its use leads to an improvement in abdominal pain and bowel dysfunction as well as global well-being, at the expense of remarkably few adverse effects. " 04/01/2003 - "In clinical trials with tegaserod, the Subject's Global Assessment (SGA) of Relief (a global measure that includes overall wellbeing, abdominal pain/discomfort, and bowel function) was used to identify responders. " 01/01/2008 - "In the group with other indications to start tegaserod therapy, moderate or significant relief of abdominal pain and bloating was noted in 64% and 68% of patients, respectively. " Order ALL the reference details at left...
2.	AmylasesIBA 08/01/1991 - "The study population included 133 consecutive patients with a chief complaint of abdominal pain who had amylase drawn over a 2-week period at a university hospital ED. " 12/01/2008 - "Serum amylase levels before and 24 hours after ERCP, and abdominal pain were recorded. " 12/01/2007 - "No significant differences were seen between the groups concerning levels of amylase, CRP, leukocytes, abdominal pain or number of gastrointestinal symptoms. " 10/01/2007 - "RESULTS: Compared with those in the control group, the alleviating time of clinical symptoms, such as abdominal pain and distention, time of hospitalization and time of blood amylase recovery in the treated group were shorter, with lesser complications and lower rate of transferring to operation (all with P < 0.05), showing a better efficacy in all aspects, but the mortality in the two groups was not different (P > 0.05). " 06/01/2007 - "Levels of amylase, the incidence of abdominal pain, and other complications occurred similarly. " Order ALL the reference details at left...
3.	Anti-Bacterial Agents (Antibiotics)IBA 02/01/1995 - "Of 40 patients admitted with a duration of abdominal pain of less than 72 h, 20 received antibiotics intravenously for 2 days followed by oral treatment for 8 days and 20 considered as controls were randomized to surgery. " 10/01/1991 - "It is concluded that if women complain of chronic lower abdominal pain laparoscopic evaluation should be carried out to confirm the diagnosis of PID to avoid unnecessary prescription of antibiotics." 03/01/1991 - " She had experienced 3 episodes of lower abdominal pain treated with antibiotics and spasmolytic. " 07/10/1989 - " 2 patients complained of abdominal pain postoperatively and were treated with antibiotics for suspected perimetritis. " 04/01/1976 - "Three case histories illustrate the diagnostic dilemma encountered whenever a patient with CF who is receiving antibiotics is evaluated for abdominal pain. " Order ALL the reference details at left...
4.	Misoprostol (Cytotec)FDA LinkGeneric 04/01/2008 - "Self-administered vaginal misoprostol of 1000 micrograms at home the evening before operative hysteroscopy is safe and highly acceptable, although a small proportion of women experienced severe lower abdominal pain. " 11/01/2005 - "Only 2 women (3.9%) experienced mild lower abdominal pain after misoprostol application. " 07/01/2004 - "Lower abdominal pain peaked at 1 and 2 hours after oral misoprostol, while it did so at 2 and 3 hours after vaginal misoprostol. " 05/01/2001 - "The increased blood pressure, as for the trend towards increased abdominal pain, may be secondary to the uterotonic effect of misoprostol. " 05/01/2002 - "CONCLUSION: Intravaginal 400 microg misoprostol is significantly more effective for termination of blighted ovum than placebo, but lower abdominal pain and fever are signifcantly higher in the misoprostol group." Order ALL the reference details at left...
5.	Morphine (MS Contin)FDA LinkGeneric 01/01/2003 - "STUDY DESIGN: The study was a prospective, double-blind clinical trial in which adult Emergency Department (ED) patients with undifferentiated abdominal pain were randomized to receive placebo (control group, n = 36) or morphine sulphate (MS group, n = 38). " 11/01/1997 - "We conducted a randomized, prospective, placebo-controlled trial to investigate changes in physical examination following the administration of placebo, 5 mg, or 10 mg of morphine to 49 patients with acute abdominal pain. " 12/01/2008 - "INF was used most commonly for fractures and morphine for abdominal pain. " 08/01/2006 - "ED patients with acute abdominal pain were randomized in a double-blind fashion to 0.1 mg/kg intravenous morphine or placebo. " 08/01/2006 - "We test the hypothesis that morphine given to emergency department (ED) patients with acute abdominal pain will reduce discomfort and improve clinically important diagnostic accuracy. " Order ALL the reference details at left...
6.	Lactose FDA LinkGeneric 05/01/2003 - "A trial of dietary lactose restriction may be beneficial in reducing abdominal pain in children with lactose maldigestion." 05/21/1994 - "A lactose-free diet was proposed and led to the disappearance of abdominal pain in 24% and a clear improvement in 32%. " 05/15/1985 - "Incomplete lactose absorption is a relatively benign condition that can be added to the differential diagnosis of gas-fluid levels in the colon and may account for some cases of spontaneous resolution of clinical and radiologic signs in children presenting with acute recurrent abdominal pain." 06/01/1981 - "This result compared with improvement occurring in five of 12 (42%) absorbers with recurrent abdominal pain who received a regular diet for one year and suggests that the elimination of lactose will not affect the overall frequency of improvement in recurrent abdominal pain. " 05/01/2003 - "There was a significant increase in abdominal pain experienced by study participants during the lactose ingestion period when compared to the lactose-free period. " Order ALL the reference details at left...
7.	Prednisolone (Predate)FDA LinkGeneric 07/01/2003 - "Although lamina propria T-lymphocyte counts decreased significantly after prednisolone (22.0% +/- 5.6%, P = 0.003), but not after placebo (11.5% +/- 8.6%, P = 0.1), this was not associated with any significant treatment-related improvement in abdominal pain, diarrhoea, frequency or urgency. " 02/01/2004 - "His abdominal pain and muscle involvement improved 1 week after commencing oral prednisolone therapy. " 10/01/1999 - "The patient improved with conservative treatment but complained of abdominal pain when the prednisolone (PSL) dose was decreased. " 06/01/2008 - "The patient was referred to our hospital because of severe abdominal pain that was unresponsive to prednisolone. " 03/01/2005 - "Seventeen days after operation, intermittent abdominal pain occurred again, and subsided upon 30 mg per day treatment with prednisolone. " Order ALL the reference details at left...
8.	Omeprazole (Esomeprazole)FDA LinkGeneric 11/15/2004 - "CONCLUSION: The study demonstrated significant problems in the current classification of dyspepsia: 'the most bothersome symptom' was not independently related to the omeprazole effect and, in patients with abdominal pain, the response to omeprazole was dependent on the presence or absence of other dyspeptic symptoms. " 03/01/2005 - "The frequency and severity of three symptoms (heartburn, acid regurgitation and upper abdominal pain) were assessed before and at the end of one month treatment with esomeprazole 40 mg once daily. " 03/01/2004 - "RESULTS: Before omeprazole therapy rebounding was observed in 94% children, heartburn in 84%, vomits in 38% and abdominal pain in 90% children. " 09/01/1998 - "Significant between group differences favoring omeprazole were also observed in GSRS total scores (p<0.0001), abdominal pain scale scores (p = 0.003), and indigestion scale scores (p = 0.003), Impact on Daily Activities (p = 0.001), PGWB positive well-being (p = 0.015), anxiety (p = 0. " 03/01/1995 - "CONCLUSIONS: These findings indicate that (1) peptic esophagitis was a common cause of chronic abdominal pain in pediatric patients and (2) omeprazole was effective in the treatment of esophagitis in children and adolescents that was resistant to high-dose histamine2-receptor antagonists." Order ALL the reference details at left...
9.	alosetron (Lotronex)FDA Link 07/01/2006 - "Alosetron, a 5-HT(3) antagonist, is superior to placebo for reducing bowel frequency, improving stool consistency, and relieving abdominal pain in women with D-IBS. " 03/01/2000 - "In clinical trials in patients with IBS, alosetron 1 mg twice daily was effective in relieving abdominal pain and discomfort. " 08/01/2006 - "Alosetron improved abdominal pain and discomfort and stool consistency in both female and male patients, but it did not improve other symptoms (sense of urgency, stool frequency and bloating) in male patients. " 11/01/2003 - "Studies involving healthy volunteers and IBS patients have demonstrated a beneficial effect of treatment with alosetron on global IBS symptoms, abdominal pain and discomfort, altered bowel function as well as improvement of quality of life (QOL). " 12/01/2002 - "Favorable satisfaction ratings for alosetron were assigned to the five medication attributes that patients considered to be most important, including relief of urgency (68% alosetron vs 41% placebo), speed of relief (71% vs 40%), time to return to normal activities (75% vs 49%), relief of abdominal pain (62% vs 44%), and prevention of return of urgency (68% vs 42%). " Order ALL the reference details at left...
10.	BariumIBA 09/01/2002 - "METHODS: After ruling out the more obvious causes of abdominal pain by barium studies, gastrointestinal endoscopies, and biochemical studies, blood lead levels were estimated by atomic absorption spectrophotometry. " 08/01/2002 - "As such, barium studies have a role in clarifying the differential diagnosis of patients with abdominal pain and altered gut function. " 11/01/2001 - "PURPOSE: A clinical evaluation of hydro-MRI as an alternative method to barium studies in children with abdominal pain of unknown origin is presented. " 02/01/2009 - "METHODS: Sixty-seven cases with chronic abdominal pain underwent a previous negative gastroscopy, colonoscopy, gastrointestinal barium, B ultrasound and electrocardiogram were received double balloon enteroscopy during June 2005 to June 2008. " 01/01/1994 - "We report the barium meal and computed tomography findings of a 70-year-old man who presented with a long history of postprandial abdominal pain." Order ALL the reference details at left...

Therapies and Procedures

1.	Cholecystectomy 01/01/1989 - "The authors believe that elective cholecystectomy is to be recommended (emergency cholecystectomy is associated with a high morbidity) as the children operated were improved by surgery, with resolution of abdominal pain." 01/01/1998 - "Although more than one-third complained of abdominal pain after cholecystectomy, 93% had improved or were cured. " 11/01/2006 - "Of the patients whose symptoms improved, those who underwent cholecystectomy had a quicker resolution of abdominal pain than those who did not undergo surgery. " 05/01/1994 - "Subsequent operations included cholecystectomy (35%), pseudocyst drainage (32%), splanchnicectomy (16%), and pancreatic biopsy (16%); and eliminated abdominal pain in 24 patients (83%). " 11/28/1992 - "Gallbladder pathology was responsible for the abdominal pain and the febrile general condition which was relieved by cholecystectomy." Order ALL the reference details at left...
2.	Drug Therapy (Chemotherapy) 05/01/2008 - "The abdominal pain and appetite loss improved after the first course of chemotherapy, and therapeutic efficacy was rated PR. " 12/01/1994 - "A 43 year old woman in remission from acute myeloid leukaemia developed abdominal pain, severe melaena, diarrhoea and gram-negative septicaemia whilst severely pancytopenic following consolidation chemotherapy. " 08/01/1991 - "Chest X ray findings improved after 4 months' antituberculous chemotherapy, but he complained of right lower abdominal pain and a mass with tenderness. " 11/01/1983 - "5) Obstinate abdominal pain and abnormal liver function remarkably were improved during the chemotherapy in 11 of 18 cases (61%), and 6 of 46 cases (13 %), respectively. " 01/01/2003 - "One trial found that drug therapies which reduce gastric acidity improve gastro-intestinal symptoms such as abdominal pain. " Order ALL the reference details at left...
3.	Enema (Enemas) 01/01/2004 - "The author suggests that the ROME II criteria for FFR could be improved by including the following additional items: a history of BMs that obstruct the toilet, a history of chronic abdominal pain relieved by enemas or laxatives, and the presence of an abdominal fecal mass or rectal fecal mass." 11/01/2005 - "The patient developed abdominal pain approximately 3.5 h after a pre-procedural enema was administered. " 07/01/2004 - "The RS procedure provided excellent continence control, with a shortening of the enema duration, a lower fluid volume, and good cosmesis, and without any ACE-related abdominal pain. " 10/01/2003 - "He administered rectal enema using a garden hose directly connected to the water two hours before admission, until he felt a sudden sharp abdominal pain. " 04/01/2001 - "Seventeen continued to experience abdominal pain, and 13 still used laxatives and enemas. " Order ALL the reference details at left...
4.	Aftercare (After-Treatment) 01/01/2008 - "The minimum duration of therapy considered was one week, and studies had to report either a global assessment of cure or improvement in symptoms, or cure of or improvement in abdominal pain, after treatment. " 07/01/2008 - "The symptoms of hemafecia and abdominal pain were improved, the disease active index (DAI) was lowered after treatment in both groups (P <0.01), but the improvement of hemafecia, time of disappearance of mucous bloody stool and decrease of DAI in the treatment group were superior to those in the control group (P <0.05 or P <0.01). " 01/01/1983 - "Frequency, stool consistency, abdominal pain and signs of venous stasis improved after treatment. " 06/01/2009 - "The total efficacy in them was compared, and data of scoring on stool (Bristol method), abdominal pain, abdominal distension, and mental condition were collected before treatment and 2 and 4 weeks after treatment. " 11/01/2007 - "After treatment for 4 weeks, there was significant difference in the scores of postprandial fullness, early satiation, abdominal pain and total symptom score as well as the effective rate of every symptom and total effective rate between Group A or B and Group C (P < 0.05). " Order ALL the reference details at left...
5.	Appendectomy 09/01/2005 - "The therapeutic value of elective laparoscopic appendectomy in the management of chronic abdominal pain." 06/01/1999 - "Three patients had undergone previous diagnostic explorations for abdominal pain, the appendix was not removed, and a subsequent appendectomy relieved the discomfort. " 01/01/1998 - "Sonographic diagnosis of right sided abdominal pain helped to reduce the risk of restricted indication for diagnostic laparoscopy respectively appendectomy by reducing the number of unnecessary operations without relevant change of perforation rate." 11/01/1980 - "Ninety-six per cent of these 70 children had been relieved of their recurrent abdominal pain by appendectomy. " 07/01/2009 - "Due to the complex nature of confirming the diagnosis of pelvic and abdominal pain, this study supports the routine performance of an incidental appendectomy in the female patient." Order ALL the reference details at left...

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