More on hepatic granulomas.

Abstract

We have read the case report of Nihon-Yanagi et al. The patient they described developed hepatic granuloma two times and the granulomatous lesion was surrounding metal staples/clips suggesting that the granuloma was due to surgical staples/clips. Hepatic granulomas (HGs) are reported in around 5% of patient who undergo a liver biopsy and caused by several diseases including sarcoidosis, tuberculosis, hydatid cyst, brucellosis, typhoid fever, chronic hepatitis B and C and primary biliary cirrhosis (PBC). Chronic hepatitis B and C infections are the most common and serious causes of liver damage in patient with renal failure. Their prevalence is a higher than people without renal failure. We have previously reported that the prevalences of HGs in patients with chronic hepatitis B and C are 1.5 and 1.3% respectively. The described patient was on hemodialysis for 12 years. The other causes of HG seem excluded; however hepatitis B and C infections and PBC should have been tested and excluded before ascribing the HGs to surgical staples/clipping material.

• Authors: Resat Ozaras, Mucahit Yemisen, Ilker Inanc Balkan
• Journal: Diagnostic pathology (Diagn Pathol) Vol. 10 Pg. 203 (Nov 19 2015) ISSN: 1746-1596 [Electronic] England
• PMID: 26586239 (Publication Type: Letter, Comment)

Chemical References

• Titanium

Topics

• Granuloma, Foreign-Body (etiology)
• Hepatectomy (adverse effects)
• Humans
• Hypersensitivity (etiology)
• Laparoscopy (adverse effects)
• Liver Neoplasms (surgery)
• Male
• Sigmoid Neoplasms (surgery)
• Surgical Instruments (adverse effects)
• Sutures (adverse effects)
• Titanium (adverse effects)