1. The concentration of ATII in
respiratory failure group was higher than that in the healthy people and in the
COPD patients. The activity of ACE was lower and PRA was higher in the
respiratory failure group than those in the other groups. 2. ATII in the dead was higher than that in the remittent. 3. After
oxygen treatment, ATII of the patients with PaO2 greater than 8.0 kPa was lower than that of the patients with PaO2 less than 8.0 kPa, but ACE and PRA of the former were lower than those of the latter. 4. ATII and ACE of the
respiratory failure group were closely related to PaO2. It was concluded that during
hypoxemia one of the responses to high ATII in the human body was the decrease of ACE. But both the increase of PRA and the insufficient decrease of ACE in the patients with
respiratory failure enhance the concentration of ATII. Also the concentration of ATII was related to the prognosis of the patients, and merely supplying the patient with
oxygen cannot restore normal ATII. So, in addition to
oxygen treatment, it is significant to inhibit PRA and ACE and use ATII as an
indicator while dealing with
cor pulmonale with cardiac and
respiratory failure.