Abstract | BACKGROUND: METHODS: RESULTS:
Diarrhea occurred most frequently in children ≤4 years (95%); abdominal pain in the lower right quadrant was most common in children 5-14 years of age (63%). Twenty-seven per cent of patients were hospitalized, 37% were treated with antimicrobials. In 6% of yersiniosis patients ≥5 years of age, appendectomies were performed. Self-reported symptoms consistent with ReA were reported by 12% of yersiniosis patients compared to 5% in a reference group not exposed to yersiniosis. Symptoms consistent with EN were reported by 3% of yersiniosis patients compared to 0.1% in the reference group. Symptoms of conjunctivitis occurred with the same frequency in yersiniosis patients and the reference group. CONCLUSIONS: Acute Y. enterocolitica infections cause considerable burden of illness with symptoms lasting for about 10 days and hospitalizations in more than a quarter of patients. The proportion of yersiniosis patients treated with antimicrobial drugs appears to be relatively high despite guidelines recommending their use only in severe cases. Appendectomies and post-infectious complications (ReA and EN) are more frequently reported in yersiniosis patients than in the reference group suggesting that they can be attributed to infections with Y. enterocolitica. Physicians should keep recent Y. enterocolitica infection in mind in patients with symptoms resembling appendicitis as well as in patients with symptoms of unclear arthritis.
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Authors | Bettina M Rosner, Dirk Werber, Michael Höhle, Klaus Stark |
Journal | BMC infectious diseases
(BMC Infect Dis)
Vol. 13
Pg. 236
(May 23 2013)
ISSN: 1471-2334 [Electronic] England |
PMID | 23701958
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Bacterial Agents
- PHB2 protein, human
- Prohibitins
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Topics |
- Adolescent
- Adult
- Anti-Bacterial Agents
(therapeutic use)
- Appendectomy
- Case-Control Studies
- Child
- Child, Preschool
- Diarrhea
(microbiology)
- Female
- Germany
(epidemiology)
- Hospitalization
- Humans
- Male
- Prohibitins
- Risk Factors
- Yersinia Infections
(diagnosis, drug therapy, physiopathology)
- Yersinia enterocolitica
(isolation & purification)
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