Type III membranoproliferative glomerulonephritis in a patient with primary Sjögren's syndrome.

Abstract

Renal involvement in the form of glomerulonephritis in Sjögren's syndrome (SS) is less common and usually a latent sequel in the course of the disease. We report a patient with Type III membarnoproliferative glomerulonephritis (MPGN) with hypothyroidism, which precedes the onset of the clinical manifestation of SS. She received immunosuppressions consisting of i.v. cyclophosphamide and high-dose corticosteroid and subsequently oral corticosteroid resulting in complete remission of nephrotic syndrome. To our knowledge, this is the first report of successfully treated Type III MPGN associated with SS.

• Authors: In O Sun, Yu Ah Hong, Hoon Suk Park, Sun Ryoung Choi, Seok Hui Kang, Byung Ha Chung, Bum Soon Choi, Yeong Jin Choi, Chul Woo Yang, Yong Soo Kim, Cheol Whee Park
• Journal: Clinical nephrology (Clin Nephrol) Vol. 79 Issue 2 Pg. 171-4 (Feb 2013) ISSN: 0301-0430 [Print] Germany
• PMID: 22967808 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins

Topics

• Adult
• Female
• Glomerulonephritis, Membranoproliferative (complications)
• Humans
• Immunoglobulins (analysis, immunology)
• Immunohistochemistry
• Kidney (chemistry, immunology)
• Sjogren's Syndrome (complications)