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Cyclophosphamide (Cytoxan)

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Also Known As:
Cytoxan; Neosar; (+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate; B-518; Cyclophosphamide Anhydrous; Cyclophosphamide Monohydrate; Cyclophosphamide, (R)-Isomer; Cyclophosphamide, (S)-Isomer; Cyclophosphane; Cytophosphan; Cytophosphane; Endoxan; NSC-26271; Procytox; Sendoxan; B 518; B518; NSC 26271; NSC26271
Networked: 25473 relevant articles (2932 outcomes, 4365 trials/studies)

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Drug Context: Research Results

Experts

1. Jones, Richard J: 63 articles (01/2022 - 07/2002)
2. Mohty, Mohamad: 51 articles (10/2022 - 10/2013)
3. Luznik, Leo: 51 articles (01/2022 - 05/2008)
4. Fuchs, Ephraim J: 49 articles (10/2022 - 05/2008)
5. Nagler, Arnon: 49 articles (10/2022 - 10/2013)
6. Blaise, Didier: 45 articles (10/2022 - 01/2015)
7. Labopin, Myriam: 45 articles (10/2022 - 10/2013)
8. Hortobagyi, Gabriel N: 45 articles (01/2022 - 01/2002)
9. Brodsky, Robert A: 43 articles (11/2020 - 03/2002)
10. Ciceri, Fabio: 41 articles (10/2022 - 01/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Lymphoma (Lymphomas)
4. Lupus Nephritis
5. Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)

Related Drugs and Biologics

1. Doxorubicin (Adriamycin)
2. Vincristine (Oncovin)
3. Prednisone (Sone)
4. Rituximab (Mabthera)
5. Etoposide (VP 16)
6. Prednisolone (Predate)
7. Methotrexate (Mexate)
8. Adrenal Cortex Hormones (Corticosteroids)
9. Steroids
10. Fluorouracil (Carac)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Combination Drug Therapy (Combination Chemotherapy)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Transplantation