Abstract | PURPOSE: METHODS: RESULTS: CONCLUSION: The assessed combination of statins with thiazolidinediones shows a synergistic cytotoxic effect against glioblastoma cells in vitro, which could represent a feasible therapeutic schema.
|
Authors | Jorge Humberto Tapia-Pérez, Elmar Kirches, Christian Mawrin, Raimund Firsching, Thomas Schneider |
Journal | Cancer chemotherapy and pharmacology
(Cancer Chemother Pharmacol)
Vol. 67
Issue 5
Pg. 1193-201
(May 2011)
ISSN: 1432-0843 [Electronic] Germany |
PMID | 21120479
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Antineoplastic Agents
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Thiazolidinediones
- Caspase 3
|
Topics |
- Animals
- Antineoplastic Agents
(pharmacology)
- Brain Neoplasms
- Caspase 3
(metabolism)
- Cell Hypoxia
- Cell Line, Tumor
- Drug Screening Assays, Antitumor
- Drug Synergism
- Glioma
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
(pharmacology)
- Rats
- Thiazolidinediones
(pharmacology)
|