Abstract |
This retrospective review presented the prevalence and manifestations of tuberculosis among renal transplant recipients in our center between 1987 and mid 2007. The prevalence of tuberculosis was 5/151 (3.3%) recipients with a median age of 49 years (range = 38-55). The median time of diagnosis after transplantation was 23 months (range = 1-47). All five patients had pulmonary tuberculosis. None developed extrapulmonary infection. Presenting symptoms were fever (60%), productive cough (80%), weight loss (40%), and hemoptysis (20%). One patient had non-parathyroid-related hypercalcemia. Cyclosporine dosage needed to be increased in all patients. Two subjects who experienced side effects of hepatitis and/or jaundice from rifampicin were switched to second-line drugs. Infection with Mycobacterial tuberculosis is a not uncommon problem in renal transplant recipients especially in endemic areas. Tuberculosis must be excluded for immunosuppressed patients with clinical or radiological suspicion.
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Authors | P Ruangkanchanasetr, C Natejumnong, S Kitpanich, A Chaiprasert, L Luesutthiviboon, T Supaporn |
Journal | Transplantation proceedings
(Transplant Proc)
Vol. 40
Issue 7
Pg. 2380-1
(Sep 2008)
ISSN: 0041-1345 [Print] United States |
PMID | 18790240
(Publication Type: Journal Article)
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Topics |
- Adult
- Female
- Humans
- Kidney Transplantation
(adverse effects)
- Male
- Middle Aged
- Opportunistic Infections
(epidemiology)
- Prevalence
- Thailand
- Tuberculosis, Pulmonary
(epidemiology)
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