[An successful case of combined daily oral administration of UFT and low-dose etoposide for multiple metastases of lung cancer].

Abstract

The authors treated a 49-year old female patient, who had multiple metastases of lung cancer, by combined daily oral administration of UFT and low-dose ETP. She was admitted to our hospital due to complaints of cough and dyspnea, and multiple nodular shadows were seen in both lungs on chest X-rays. The pulmonary lesion was diagnosed as pulmonary metastasis of lung cancer (squamous cell car) by lung biopsy under CT-guide. She also had bone metastasis of the ribs and cerebellar metastasis from the lung cancer. Combination chemotherapy of UFT 300 mg/body daily and etoposide 25 mg/body daily was performed for 13 months. The pulmonary metastatic tumors were reduced significantly. No side effects of the carcinostatic agents were noted. She is now doing well. Combined daily oral administration of UFT and low-dose etoposide is considered to be safe and effective, and the treatment useful for recovering QOL in advanced lung cancer patients.

• Authors: M Imaizumi, M Takeuchi, Y Seki, H Yoshioka, K Yamada
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 27 Issue 7 Pg. 1035-8 (Jul 2000) ISSN: 0385-0684 [Print] Japan
• PMID: 10925690 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Tegafur
• Uracil
• Etoposide

Topics

• Administration, Oral
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Carcinoma, Squamous Cell (drug therapy)
• Drug Administration Schedule
• Etoposide (administration & dosage)
• Female
• Humans
• Lung Neoplasms (drug therapy)
• Middle Aged
• Neoplasms, Multiple Primary (drug therapy)
• Tegafur (administration & dosage)
• Uracil (administration & dosage)