Central Nervous System Cysts (Suprasellar Cyst)

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37 relevant articles (1 outcomes, 1 trials/studies) found for this Disease

Description: Congenital or acquired cysts of the brain, spinal cord, or meninges which may remain stable in size or undergo progressive enlargement.

Also Known As:

Suprasellar Cyst; Rathke's Cleft Cysts; Cleft Cysts, Rathke's; Cyst, Suprasellar; Cysts, Rathke Cleft; Cysts, Suprasellar; Rathkes Cleft Cysts; Suprasellar Cysts; Cysts, Central Nervous System; Rathke Cleft Cysts

Relationship Network

Disease Context: Research Results

Neoplasms: 387349

Neoplasms by Site: 1

Nervous System Neoplasms: 143

Central Nervous System Neoplasms: 245

Central Nervous System Cysts: 37

Arachnoid Cysts: 219

Nervous System Diseases: 3414

Nervous System Neoplasms: 143

Central Nervous System Neoplasms: 245

Central Nervous System Cysts: 37

Arachnoid Cysts: 219

Nervous System Malformations: 21

Central Nervous System Cysts: 37

Arachnoid Cysts: 219

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 421

Congenital Abnormalities: 9330

Nervous System Malformations: 21

Central Nervous System Cysts: 37

Arachnoid Cysts: 219

Related Diseases

1.	Craniopharyngioma (Craniopharyngiomas)
2.	Neoplasms (Cancer)
3.	Pituitary ACTH Hypersecretion
4.	Prolactinoma (Prolactinomas)
5.	Acromegaly

Experts

1.	Fahlbusch, Rudolf: 1 article (12/2006)
2.	Hofmann, Bernd M: 1 article (12/2006)
3.	Buchfelder, Michael: 1 article (12/2006)
4.	Buslei, Rolf: 1 article (12/2006)
5.	Blümcke, Ingmar: 1 article (12/2006)
6.	Kreutzer, Jürgen: 1 article (12/2006)
7.	Saeger, Wolfgang: 1 article (12/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Central Nervous System Cysts:

1.	ProlactinIBA 02/01/2003 - "At a median follow-up period of 16 months (range 3-45 months), surgical remission rates were as follows: in 40 patients with endocrine-inactive macroadenomas, 95% for noninvasive and 40% for invasive tumors; in the 20 patients with prolactinomas, 75% for prolactinomas with an initial prolactin (PRL) level lower than 200 ng/ml, 33% for those with a PRL level between 200 and 600 ng/ml, and 0% for those with a PRL level higher than 1400 ng/ml; in the 15 patients with Cushing disease, 73% for microadenomas and 25% for macroadenomas; in the 10 patients with acromegaly, 75% for microadenomas and 50% for macroadenomas; in the five patients with Rathke cleft cysts, 80%; and in the five patients with craniopharyngiomas, 40%" Order ALL the reference details at left...
2.	Colloids (Colloid)IBA 10/01/1993 - "We present the immunohistochemical study of 11 cases of intracranial cysts: two extraventricular ependymal cysts, three colloid cysts of the third ventricle, four extraventricular choroidal cysts and two Rathke's cleft cysts" 10/01/1993 - "This finding supports the neuroepithelial origin for choroid and ependymal cysts, and an endodermal nature for colloid and Rathke's cleft cysts" 01/01/1993 - "Colloid cysts, Rathke's cleft cysts and epithelial cysts in the spinal canal expressed complex type cytokeratins, while enterogenous cysts and neuroectodermal cysts showed only simple type cytokeratins" 01/01/1990 - "Colloid cysts of the third ventricle, Rathke's cleft cysts in the sella and epithelial cysts in the spinal canal expressed complex type cytokeratins while enterogenous cysts and neuro-ectodermal cysts showed only simple type cytokeratins" 01/01/1995 - "Pathological and immunohistochemical profiles were consistent with neurenteric cysts, Rathke's cleft cysts or colloid cysts and was also in keeping with an endodermal origin" Order ALL the reference details at left...
3.	beta CateninIBA 12/01/2006 - "Nuclear beta-catenin accumulation as reliable marker for the differentiation between cystic craniopharyngiomas and rathke cleft cysts: a clinico-pathologic approach." 06/01/2005 - "Furthermore, the expression pattern of beta-catenin was immunohistochemically analysed in a cohort of tumours and cysts of the sellar region including pituitary adenomas (n=58), craniopharyngiomas (n=57), arachnoidal cysts (n=8), Rathke's cleft cysts (n=10) and xanthogranulomas (n=6)" Order ALL the reference details at left...
4.	Gadolinium DTPA (Magnevist)FDA Link 03/01/1994 - "MR imaging with gadopentetate dimeglumine does assist in the diagnosis of Rathke cleft cysts" 07/01/1994 - "We compared the position of the normal pituitary gland as estimated by gadolinium (Gd)-DTPA-enhanced MRI, with its position at surgery in 40 patients with intra- and juxtasellar tumours: 22 pituitary adenomas, 4 craniopharyngiomas, 7 meningiomas, 2 germinomas, and 5 Rathke cleft cysts" Order ALL the reference details at left...
5.	Growth Hormone (Somatotropin)IBA 01/01/1995 - "Rathke's cleft cysts within a growth hormone producing pituitary adenoma." 05/01/2004 - "In childhood, the most common presenting symptoms of Rathke's cleft cysts are endocrine abnormalities, such as reduced growth hormone secretion, hyperprolactinemia, or diabetes insipidus" Order ALL the reference details at left...
6.	SiliconesIBA 06/01/2002 - "Silicone plates were used in 10 patients who had 7 pituitary adenomas, 2 Rathke's cleft cysts, and 1 metastatic tumor" 06/01/1998 - "METHODS: A silicone plate was used to reconstruct the sellar floor in 69 consecutive patients with sellar tumors that included 60 pituitary adenomas and nine Rathke's cleft cysts" Order ALL the reference details at left...
7.	S100 Proteins (S 100 Protein)IBA 01/01/1993 - "Many cells of follicles in the pars intermedia as well as individual cells of five Rathke's cleft cysts were also immunoreactive for chromogranin, S-100 protein, GFAP, and pituitary hormones" 11/01/2003 - "Chordoid glioma was immunoreactive for glial fibrillary acidic protein, S-100 protein and vimentin, and focally positive for epithelial membrane antigen and CD34, while cytokeratin highlighted epithelial cells lining Rathke's cleft cysts" Order ALL the reference details at left...
8.	MucinsIBA 05/01/1997 - "The lining cells and mucin of Rathke's cleft cysts also revealed CA19-9" 07/01/1985 - "A tumor of Rathke's cleft origin was studied, which showed some histologic features consistent with craniopharyngioma, but also had ciliated and mucin-containing cells more commonly observed in Rathke's cleft cysts" Order ALL the reference details at left...
9.	Keratins (Keratin)IBA 10/01/2002 - "RESULTS: Craniopharyngiomas had a cytokeratin expression pattern distinct from that of Rathke cleft cysts and pituitary gland pars intermedia: craniopharyngiomas did not express cytokeratins 8 and 20, whereas Rathke cleft cysts and pars intermedia of pituitary glands both expressed cytokeratins 8 and 20" 11/01/2003 - "Chordoid glioma was immunoreactive for glial fibrillary acidic protein, S-100 protein and vimentin, and focally positive for epithelial membrane antigen and CD34, while cytokeratin highlighted epithelial cells lining Rathke's cleft cysts" Order ALL the reference details at left...
10.	CholesterolIBA 01/01/1999 - "CONCLUSION: The unique MR finding of Rathke cleft cysts--high signal intensity on T1-weighted images and low signal intensity on T2-weighted images--might depend mainly on protein concentration, not on cholesterol." 10/01/1994 - "The high signal intensity in magnetic resonance images of Rathke's cleft cysts may be explained by hemorrhage and a deposition of cholesterol crystal and may be considered in certain cases of Rathke's cleft cyst, especially when they are large." Order ALL the reference details at left...

Therapies and Procedures

1.	Colonic Pouches (S Pouch) 05/01/2004 - "Rathke's cleft cysts arise from remnants of Rathke's pouch and are usually found incidentally on MRI or autopsy" 11/01/1995 - "Rathke's cleft cysts (RCCs) are considered to arise from the remnants of Rathke's pouch, an invagination of the stomodeum" 11/01/2008 - "Rathke cleft cysts (RCCs) arise from embryonic remnants of Rathke's pouch, and usually manifest as headaches, visual impairments and endocrine disturbances" Order ALL the reference details at left...
2.	Craniotomy 01/01/1989 - "By a right frontotemporal craniotomy, the suprasellar cyst was explored" 04/01/1987 - "She had a right frontal craniotomy and a suprasellar cyst was subtotally removed" Order ALL the reference details at left...
3.	Endoscopes 10/01/2005 - "Our data suggest that suprasellar cysts are well treated by endoscopic or endoscope-assisted procedures with good clinical outcome and low surgical morbidity." 10/01/2005 - "Between December 1996 and December 2003, 13 patients (7 female and 6 male patients), mean age 29 years, underwent endoscopic or endoscope-assisted procedures for suprasellar cysts at our department" Order ALL the reference details at left...

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