Glucocorticoids

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5208 relevant articles (289 outcomes, 455 trials/studies) found for this Bio-Agent

Description: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 44070

Adrenal Cortex Hormones: 17038

Glucocorticoids: 5208

Chemical Actions and Uses

Pharmacologic Actions: 50

Physiological Effects of Drugs: 1

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 44070

Glucocorticoids: 5208

Experts

1.	Storm, Gert: 6 articles (07/2008 - 01/2002)
2.	Bijlsma, J W J: 5 articles (09/2008 - 03/2003)
3.	Metselaar, Josbert M: 5 articles (07/2008 - 01/2002)
4.	Reichardt, Holger M: 5 articles (06/2008 - 06/2002)
5.	Walker, Brian R: 5 articles (05/2008 - 01/2003)
6.	Buttgereit, Frank: 4 articles (09/2008 - 11/2004)
7.	Banciu, Manuela: 4 articles (07/2008 - 01/2006)
8.	Schiffelers, Raymond M: 4 articles (07/2008 - 01/2006)
9.	Buttgereit, F: 4 articles (10/2007 - 01/2005)
10.	Kleiman, Anna: 3 articles (06/2008 - 01/2005)

Related Diseases

1.	Asthma (Bronchial Asthma) 02/27/2008 - "Although glucocorticoids are highly effective in controlling the inflammatory process in asthma, they appear to have little effect on the lower airway remodelling processes that appear to play a role in the pathophysiology of asthma at currently prescribed doses" 12/01/2006 - "Glucocorticoids (GCS) are still the most effective treatment for asthma" 03/15/2006 - "RATIONALE: Glucocorticoids (GCs) are highly effective in the treatment of asthma" 03/01/2006 - "These have proved highly effective for most asthmatic subjects, but despite these developments, there are a number of subjects with asthma who fail to respond to even high doses of inhaled or even oral glucocorticoids" 03/01/2004 - "Tertiary Al is far more common, most often secondary to iatrogenic therapy with exogenous glucocorticoids for the management of chronic diseases such as connective tissue disorders, anti-rejection regimes, and severe asthma" Get all the results and reference details, order at left...
2.	Inflammation 08/01/2005 - "Glucocorticoids are very effective in controlling the inflammation seen in asthmatic airways" 01/01/2001 - "Glucocorticoids in low doses have proven to be very effective in suppressing the inflammation associated with RA" 10/01/1997 - "Therefore the use of topically active glucocorticoids with low systemic bioactivity for the treatment of allergic inflammation may be particularly effective in modulating the cytokine activity that is an important component of the allergic response." 01/01/2002 - "Glucocorticoids may be beneficial in the fibroproliferative phase of lung injury by suppressing chronic inflammation" 07/01/2001 - "BACKGROUND: Increase in mast-cell number at sites of allergic inflammation has been observed, and glucocorticoids applied to the sites have been shown to result in a significant reduction in mast cells" Get all the results and reference details, order at left...
3.	Rheumatoid Arthritis 05/01/2007 - "Clinical studies have also had major developments, most strikingly with the publication of two randomized prospective studies on the efficacy of glucocorticoids in preventing erosions in rheumatoid arthritis" 06/01/2002 - "More than 50 years after their discovery, glucocorticoids continue to be a mainstay of treatment for many patients with rheumatoid arthritis (RA)" 10/01/2001 - "Resolved: Low-dose glucocorticoids are neither safe nor effective for the long-term treatment of rheumatoid arthritis." 09/01/2004 - "Given growing clinical and basic science evidence supporting the efficacy of glucocorticoids for the treatment of rheumatoid arthritis, their use may further increase" 05/01/2001 - "Glucocorticoids provide a large, immediate improvement in the symptoms of rheumatoid arthritis" Get all the results and reference details, order at left...
4.	Syndrome 10/01/2006 - "Since the first description of the syndrome, results from long-term exposure to glucocorticoids has not been improved upon, but our understanding of its pathophysiologic features and our ability to diagnose and treat the disorder have increased dramatically" 09/01/2002 - "Although the use of some of these substances, for example glucocorticoids, remains controversial, others may prove beneficial in the treatment of this syndrome" 11/01/2004 - "The latter may further enhance adrenal and/or ovarian androgen secretion, decrease the therapeutic efficacy of glucocorticoids and contribute to later development of the metabolic syndrome and its complications." 06/01/1986 - "Antepartum glucocorticoids are effective in reducing the incidence and severity of respiratory distress syndrome" 04/01/2003 - "Satoyoshi syndrome in a Caucasian girl improved with glucocorticoids--a clinical report." Get all the results and reference details, order at left...
5.	Infection 03/15/1999 - "These results conclusively demonstrate the importance of induced endogenous glucocorticoids in protection against life-threatening effects resulting from infection-elicited cytokine responses" 06/23/2007 - "Twenty-seven dogs enrolled in a study of ASIT were clinically assessed four times over a period of nine months; their requirement for treatment for secondary bacterial and yeast infections, for the administration of glucocorticoids as additional antipruritic therapy, and for the treatment of any adverse effects of the ASIT were evaluated" 01/01/2007 - "In the present study, we examined whether resistance of the HPA axis activation following intracerebral HSV-1 infection to dex-induced suppression is associated with modifications in hippocampal or pituitary glucocorticoids (GC) receptors or GC receptors in cultured astrocytes" 03/01/1994 - "Immunologic and virologic effects of glucocorticoids on human immunodeficiency virus infection in children: a preliminary study." 01/01/1991 - "Although the time course of both infections from the inoculation of fungi during rethoracotomy and immunosuppression with glucocorticoids to the lethal outcome was strikingly similar, histopathologic studies disclosed the disparate character of the two fungal pathogens responsible: the yeast Candida albicans and the angiotropic mold Aspergillus fumigatus." Get all the results and reference details, order at left...
799 Diseases and 5208 more articles analyzed in the Research Interface, order at left...

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1134 Drugs and Important Bio-Agents and 2664 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

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87 Therapies and Procedures and 268 more articles analyzed in the Research Interface, order at left...

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