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Keratins (Keratin)

A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Also Known As:
Keratin; Cytokeratin; Keratin-Associated Proteins; alpha-Keratin; Associated Protein, Keratin; Keratin Associated Proteins; Protein, Keratin Associated; alpha Keratin; Keratin Associated Protein
Networked: 10369 relevant articles (162 outcomes, 957 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Omary, M Bishr: 42 articles (12/2022 - 02/2002)
2. Terada, Tadashi: 39 articles (07/2015 - 01/2008)
3. Strnad, Pavel: 27 articles (11/2020 - 02/2003)
4. Magin, Thomas M: 26 articles (12/2022 - 07/2002)
5. Epstein, Jonathan I: 26 articles (12/2019 - 09/2002)
6. Moran, Cesar A: 24 articles (01/2021 - 04/2002)
7. Pantel, Klaus: 23 articles (01/2022 - 01/2002)
8. Coulombe, Pierre A: 21 articles (01/2020 - 02/2002)
9. Tsubura, Airo: 21 articles (06/2016 - 01/2006)
10. McLean, W H Irwin: 20 articles (03/2016 - 02/2002)

Related Diseases

1. Neoplasms (Cancer)
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3. Adenocarcinoma
4. Wounds and Injuries (Trauma)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

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9. Monoclonal Antibodies
10. Biomarkers (Surrogate Marker)

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5. Decompression