Nonsense Codon (Nonsense Mutation)

An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
Also Known As:
Nonsense Mutation; Nonsense Mutations; Premature Stop Codon; Unassigned Codon; Codon, Nonsense; Amber Nonsense Codon; Amber Nonsense Mutation; Nonsense Codon, Amber; Ochre Nonsense Codon; Ochre Nonsense Mutation; Opal Nonsense Codon; Opal Nonsense Mutation; Premature Termination Codon; Amber Nonsense Codons; Amber Nonsense Mutations; Codon, Amber Nonsense; Codon, Ochre Nonsense; Codon, Opal Nonsense; Codon, Premature Stop; Codon, Premature Termination; Codons, Amber Nonsense; Codons, Nonsense; Codons, Ochre Nonsense; Codons, Opal Nonsense; Codons, Premature Stop; Codons, Premature Termination; Codons, Unassigned; Mutation, Amber Nonsense; Mutation, Ochre Nonsense; Mutation, Opal Nonsense; Mutations, Amber Nonsense; Mutations, Nonsense; Mutations, Ochre Nonsense; Mutations, Opal Nonsense; Nonsense Codon, Ochre; Nonsense Codon, Opal; Nonsense Codons; Nonsense Codons, Amber; Nonsense Codons, Ochre; Nonsense Codons, Opal; Nonsense Mutation, Amber; Nonsense Mutation, Ochre; Nonsense Mutation, Opal; Nonsense Mutations, Amber; Nonsense Mutations, Ochre; Nonsense Mutations, Opal; Ochre Nonsense Codons; Ochre Nonsense Mutations; Opal Nonsense Codons; Opal Nonsense Mutations; Premature Stop Codons; Premature Termination Codons; Stop Codon, Premature; Stop Codons, Premature; Termination Codon, Premature; Termination Codons, Premature; Unassigned Codons; Codon, Termination, Premature; Codon, Unassigned; Mutation, Nonsense
Networked: 1644 relevant articles (12 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Nürnberg, Gudrun: 8 articles (02/2014 - 03/2008)
2. Nürnberg, Peter: 8 articles (02/2014 - 03/2008)
3. Matsuo, Masafumi: 8 articles (06/2012 - 03/2004)
4. Takeshima, Yasuhiro: 7 articles (06/2012 - 03/2004)
5. Najmabadi, Hossein: 6 articles (03/2015 - 02/2007)
6. Rouleau, Guy A: 6 articles (01/2015 - 11/2010)
7. Baasov, Timor: 6 articles (04/2014 - 05/2009)
8. Zeviani, Massimo: 5 articles (07/2015 - 03/2007)
9. Moore, Anthony T: 5 articles (04/2015 - 01/2009)
10. Elfring, Gary L: 5 articles (10/2014 - 04/2007)

Related Diseases

1. Infection
2. Heart Failure
3. Cystic Fibrosis (Mucoviscidosis)
4. Neoplasms (Cancer)
5. Muscular Dystrophies (Muscular Dystrophy)

Related Drugs and Biologics

1. ataluren
2. Messenger RNA (mRNA)
3. RNA (Ribonucleic Acid)
4. Protein Sorting Signals (Signal Peptide)
5. Adenosine
6. Incretins
7. Tobramycin (Nebcin)
8. Glyburide (Glibenclamide)
9. AMP Deaminase (Myoadenylate Deaminase)
10. sitagliptin (Januvia)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Cord Blood Stem Cell Transplantation
4. Heart Transplantation (Grafting, Heart)
5. Transplantation (Transplant Recipients)