Protein Sorting Signals (Signal Peptide)

626  relevant articles (11 outcomes, 29 trials/studies) found for this Bio-Agent

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Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Shah, Gul N: 2 articles (12/2007 - 04/2004)
2.	Sly, William S: 2 articles (12/2007 - 04/2004)
3.	Waheed, Abdul: 2 articles (12/2007 - 04/2004)
4.	Lou, Sai: 1 article (08/2008)
5.	Fang, Jie: 1 article (08/2008)
6.	Lehtimäki, Terho: 1 article (08/2008)
7.	Pörsti, Ilkka: 1 article (08/2008)
8.	Viiri, Leena E: 1 article (08/2008)
9.	Liu, Zheng-Wen: 1 article (08/2008)
10.	Ilveskoski, Erkki: 1 article (08/2008)

Related Diseases

1.	Infection 09/01/2009 - "A large body of evidence from the past decade supports the existence, in membrane from animal and yeast cells, of functional microdomains playing important roles in protein sorting, signal transduction, or infection by pathogens. " 09/29/2006 - "This intramembrane protease cleaves within a C-terminal signal sequence in the viral core protein, but the molecular determinants of cleavage and whether it is required for infection in vivo are unknown. " 08/01/2006 - "A large body of evidence from the past decade supports the existence, in membrane from animal and yeast cells, of functional microdomains that play important roles in protein sorting, signal transduction, or infection by pathogens. " 05/25/2006 - "Further investigation of the first two protected regions by band shift assays revealed a new band that appeared in new infection cycles, suggesting that viral infection induces new factors that interact with the late leader peptide region of JCV. " 08/27/2004 - "A large body of evidence from the past decade supports the existence of functional microdomains in membranes of animal and yeast cells, which play important roles in protein sorting, signal transduction, or infection by pathogens. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 06/21/2008 - "METHODS: In this study, we designed a secretory protein by adding a secretory signal peptide (SP) to the N terminus of Transactivating Transcription (TAT)-apoptin (SP-TAT-apoptin), to test the hypothesis that it gains an additive bystander effect as an anti-cancer therapy. " 09/01/2003 - "In the present study, we investigated the feasibility of modifying a cytokine signal peptide with a tumor antigenic epitope. " 01/01/2009 - "Finally, we apply our approach to a set of recently produced large-scale cancer somatic mutations from colon and breast cancers and generate a prioritized list of mutations in signal peptides that might impair protein function." 09/16/2008 - "Splicing variation, leading to a 9-amino acid insertion in the signal peptide region, was proposed to be because of a single-nucleotide polymorphism (rs4072037) at the 5' end of exon 2, but is also reported to be cancer-associated. " 03/07/2008 - "URB/DRO1 contains N-terminal signal sequence and is thought to play a role in apoptosis of tumor cells. " Order ALL the reference details at left...
3.	Melanoma (Melanoma, Malignant) 02/21/2007 - "METHODS: KISS1 containing an internal FLAG epitope with (KFM) or without (KFMdeltaSS) a signal sequence was transfected into C8161.9 human melanoma cells, which do not express endogenous KISS1. " 03/02/2000 - "The high basal activity of the mda-7 promoter in uninduced melanoma cells and the absence of enhancing effect upon treatment with differentiation inducers is corroborated by transfection studies using the promoter region of mda-7 linked to a luciferase reporter gene containing the SV40 polyadenylation signal sequence. " 08/01/2000 - "We report here that the addition of synthetic signal sequences at the N terminus, but not at the C terminus, of an epitope from the human melanoma antigen MART-1 greatly enhances its presentation in both TAP-deficient and TAP-expressing cells. " 08/01/2000 - "Synthetic insertion signal sequences enhance MHC class I presentation of a peptide from the melanoma antigen MART-1." 03/02/2000 - "Substitution of the SV40 polyadenylation signal sequence in the luciferase reporter plasmid with the mda-7-ARE-3'-UTR renders the Luciferase message unstable when expressed in proliferating and reversibly differentiated melanoma cells. " Order ALL the reference details at left...
4.	Malaria 02/21/2003 - "The signal sequence of exported protein-1 directs the green fluorescent protein to the parasitophorous vacuole of transfected malaria parasites." 02/09/2007 - "Previous studies have shown that the immunogenicity of rodent malaria parasite-derived circumsporozoite protein (CS) can be improved by deleting the glycosyl-phosphatidyl-inositol (GPI) signal sequence. " 10/01/2006 - "Similar to other oomycete avirulence proteins, AVR3aKI carries a signal peptide followed by a conserved motif centered on the consensus RXLR sequence that is functionally similar to a host cell-targeting signal of malaria parasites. " 04/01/2004 - "A gene encoding a 352 amino acid protein with a putative signal sequence, transmembrane domain and thrombospondin structural homology repeat was identified in the genome of the human malaria parasite, Plasmodium falciparum and the rodent malaria parasite, Plasmodium berghei. " 07/04/2003 - "Mammalian expression vectors encoding region C of malaria transmission-blocking vaccine candidate Pfs230 (aa 443-1132) with and without a 3' glycosylphosphatidylinositol (GPI) anchor signal sequence were tested for their immunogenicity in mice. " Order ALL the reference details at left...
5.	Starvation 02/25/1991 - "As expected, the presence of a nonsense codon early in the leader peptide coding region decreased basal expression and eliminated starvation control. " 10/01/2005 - "Mature form of HSA was expressed under the control of the sucrose starvation-inducible rice alpha Amy3 promoter, and secretion of HSA into the culture medium was achieved by using the alpha Amy3 signal sequence. " 03/01/1994 - "Strains MC7 (csi7::phoA) and MC19 (csi19::phoA) contain fusions of a signal peptide-deficient phoA reporter sequence to a csi (carbon starvation-inducible) gene. " 12/01/1978 - "The effect of starvation for a number of the amino acids in the trp leader peptide was determined. " 04/01/2001 - "Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antigens
2.	DNA (Deoxyribonucleic Acid)
3.	Epitopes
4.	A-Form DNA (A-DNA)
5.	Histocompatibility Antigens Class I
6.	Phosphatidylinositols (Phosphatidylinositol)
7.	Proline (L-Proline)
8.	Tissue Plasminogen Activator (Alteplase)
9.	Interleukin-12 (IL 12)
10.	peptide permease

Related Therapies and Procedures

1.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
2.	Transplantation (Transplant Recipients)
3.	Ligation
4.	Bioreactors
5.	Injections