Trihexyphenidyl (Artane)

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221 relevant articles (28 outcomes, 17 trials/studies) found for this Drug

Description: One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Also Known As:

Artane; AHP Brand of Trihexyphenidyl Hydrochloride; Apo-Trihex; Apotex Brand of Trihexyphenidyl Hydrochloride; Aventis Brand of Trihexyphenidyl Hydrochloride; Cyclodol; Cypress Brand of Trihexyphenidyl Hydrochloride; Eisai Brand of Trihexyphenidyl Hydrochloride; Hexal Brand of Trihexyphenidyl Hydrochloride; Hipokinon; Lederle Brand of Trihexyphenidyl Hydrochloride; Liquipharm Brand of Trihexyphenidyl Hydrochloride; Parkinane; Parkopan; Pharmaceutical Associates Brand of Trihexyphenidyl Hydrochloride; Psicofarma Brand of Trihexyphenidyl Hydrochloride; Rugby Brand of Trihexyphenidyl Hydrochloride; Schrein Brand of Trihexyphenidyl Hydrochloride; Trihexane; Trihexyphenidyl Hydrochloride; Trihexyphenidyl Hydrochloride Elixir; Wyeth Brand of Trihexyphenidyl; Wyeth Brand of Trihexyphenidyl Hydrochloride; Apo Trihex; ApoTrihex; Elixir, Trihexyphenidyl Hydrochloride; Hydrochloride Elixir, Trihexyphenidyl; Trihexyphenidyl Wyeth Brand; Benzhexol; 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Experts

1.	Appendino, Juan Pablo: 1 article (07/2008)
2.	Soman, Teesta: 1 article (07/2008)
3.	Sherman-Levine, Sara: 1 article (05/2007)
4.	Mink, Jonathan W: 1 article (05/2007)
5.	Gaebler-Spira, Deborah: 1 article (05/2007)
6.	Child Motor Study Group: 1 article (05/2007)
7.	Welty, Leah J: 1 article (05/2007)
8.	Damiano, Diane: 1 article (05/2007)
9.	Bastian, Amy: 1 article (05/2007)
10.	Dure, Leon: 1 article (05/2007)

Related Diseases

1.	Dystonia (Limb Dystonia) 10/01/1992 - "The action dystonia was markedly improved by giving trihexyphenidyl" 02/01/1986 - "Thirty-seven per cent of the 35 idiopathic dystonia patients had a moderate to marked improvement with an average dosage of 21.5 mg of trihexyphenidyl" 09/01/1996 - "Response to medical treatment (trihexyphenidyl dose as high as 40 mg daily) in 5 patients was disappointing; 4 of the 5 patients who underwent functional stereotaxic operations were improved, but dystonia was still present at the end of the follow-up" 08/01/1999 - "The symptoms abated under therapy with trihexyphenidyl-HCL, so that the patient has been able to work as a tennis coach with improved athletic performance for the past 3 yr. It is concluded that the various forms of dystonia should be included in the differential diagnosis of impaired coordinative movements under athletic exercise, especially of the upper extremities." 01/01/2005 - "The dystonia was ameliorated but not abolished with trihexyphenidyl" Order ALL the reference details at left...
2.	Tremor (Tremors) 11/15/2007 - "We report on a patient who developed left arm rest/postural tremor at age 24 and responded well to trihexyphenidyl" 03/01/2006 - "The tremor was successfully controlled by a single high daily dose of trihexyphenidyl (38 mg) without severe or uncomfortable side effects" 01/01/2003 - "Re-administration of trihexyphenidyl decreased the tremors" 01/01/2003 - "Ten weeks after the accident, a coarse tremor in the head and right upper extremity developed after withdrawal of trihexyphenidyl" 01/01/2003 - "Administration of trihexyphenidyl decreased the tremor" Order ALL the reference details at left...
3.	Parkinsonian Disorders (Parkinsonism) 08/27/1949 - "Artane therapy for parkinsonism; a preliminary study of results in 117 cases." 11/01/2003 - "CONCLUSION: NYG has obvious efficacy enhancing and toxicity attenuating effects caused by the anti-Parkinsonism treatment with Medopa and Artane." 11/01/2003 - "METHODS: Adopting the randomized double-blinded method, the effect of adding NYG to 30 patients with Parkinsonism in the treated group, who already received anti-Parkinsonism treatment but showing decreased response to Medopa and Artane and with obvious adverse reaction, was observed and controlled by 30 patients treated by adding placebo" 11/09/1967 - "Treatment of parkinsonism with benzhexole (Artane and Artane-sequel)]" 11/01/1966 - "Treatment of parkinsonism with artane and slow release artane." Order ALL the reference details at left...
4.	Dystonic Disorders (Writer's Cramp) 05/09/1952 - "A case of writer's cramp cured by trihexyphenidyl.]" 05/01/2007 - "A prospective, open-label, multicenter pilot trial of high-dose trihexyphenidyl was conducted in 23 children aged 4 to 15 years with cerebral palsy judged to have secondary dystonia impairing function in the dominant upper extremity" 07/01/2008 - "Correspondence on "Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy"." 05/01/2007 - "Although trihexyphenidyl is used clinically to treat both primary and secondary dystonia in children, limited evidence exists to support its effectiveness, particularly in dystonia secondary to disorders such as cerebral palsy" 05/01/2007 - "Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy." Order ALL the reference details at left...
5.	Blepharospasm 01/01/1989 - "A 64-year-old woman with blepharospasm, sustained clenching of the jaw, antecollis, and a strained, high-pitched phonation continued chronic trihexyphenidyl therapy despite the lack of any obvious benefit" 01/01/1984 - "Relief of blepharospasm was achieved with clonazepan (CNZ, 1 mg i.v.) and benzhexol (BH, 5 mg i.m.) by acute parenteral administration in 5 cases of Meige's syndrome" 06/01/1985 - "Blepharospasm: a case study comparison of trihexyphenidyl (Artane) versus EMG biofeedback." 06/01/2004 - "Based on this review, we conclude: (i) botulinum toxin has obvious benefit (level A, class I-II evidence) for the treatment of cervical dystonia and blepharospasm; (ii) trihexyphenidyl in high dosages is effective for the treatment of segmental and generalized dystonia in young patients (level A, class I-II evidence); (iii) all other methods of pharmacological intervention for generalized or focal dystonia, including botulinum toxin injections, have not been confirmed as being effective according to accepted evidence-based criteria (level U, class IV studies)." 04/01/1983 - "Tetrabenazine, lithium, and trihexyphenidyl were most useful for the treatment of oromandibular dystonia, and clonazepam was useful in some patients with blepharospasm." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Levodopa (L Dopa)
2.	Trihexyphenidyl (Artane)
3.	Biperiden (Akineton)
4.	Benztropine (Benzatropine)
5.	Tetrabenazine (Nitoman)
6.	Botulinum Toxins (Botulinum Toxin)
7.	Scopolamine (Hyoscine)
8.	Clozapine (Clozaril)
9.	Amantadine (Aman)
10.	Procyclidine (Procyclidine Hydrochloride)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Analgesia
3.	Electrodes (Electrode)
4.	Biofeedback (Psychology) (Biofeedback)
5.	Aftercare (After-Treatment)

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