Duodenal Ulcer (Curling's Ulcer)

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7649 relevant articles (553 outcomes, 1116 trials/studies) found for this Disease

Description: A PEPTIC ULCER located in the DUODENUM.

Also Known As:

Curling's Ulcer; Curling Ulcer; Curlings Ulcer; Duodenal Ulcers; Ulcer, Curling; Ulcer, Duodenal; Ulcers, Duodenal

Relationship Network

Disease Context: Research Results

Digestive System Diseases: 29

Gastrointestinal Diseases: 1159

Peptic Ulcer: 6805

Duodenal Ulcer: 7649

Intestinal Diseases: 580

Duodenal Diseases: 67

Peptic Ulcer: 6805

Duodenal Ulcer: 7649

Related Diseases

1.	Ulcer
2.	Stomach Ulcer (Gastric Ulcer)
3.	Infection
4.	Hemorrhage
5.	Pain (Aches)

Experts

1.	Rapoport, S I: 4 articles (01/2006 - 04/2001)
2.	Vasil'ev, Iu V: 4 articles (01/2002 - 01/2002)
3.	Kitajima, Masaki: 3 articles (09/2008 - 07/2005)
4.	Yoshida, Masashi: 3 articles (09/2008 - 12/2004)
5.	Namiot, Z: 3 articles (06/2007 - 01/2001)
6.	Raĭkhlin, N T: 3 articles (01/2006 - 01/2003)
7.	Lanas, A: 3 articles (10/2005 - 06/2003)
8.	Svennerholm, A M: 3 articles (04/2005 - 06/2000)
9.	Konturek, S J: 3 articles (06/2002 - 01/2001)
10.	Asad, M: 3 articles (11/2001 - 06/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Duodenal Ulcer:

1.	Ranitidine (Zantac)FDA LinkGeneric 07/01/1994 - "In summary, the proven efficacy and tolerability of ranitidine will ensure its continued use in the treatment of many patients with duodenal ulcer and mild to moderate reflux oesophagitis" 06/01/1995 - "BACKGROUND: The purpose of this study was to investigate if the use of a higher night time dose of ranitidine (300 mg) could keep significantly more duodenal ulcer patients in remission than the usual maintenance dose (150 mg)" 04/01/1991 - "We conclude that ranitidine is effective in preventing NSAID-associated duodenal ulcers and may be appropriate prophylaxis for certain high-risk patients." 08/01/1992 - "These results show that in patients with acute duodenal ulcer, 300 mg ranitidine administered at the end of the evening meal provides better control of nocturnal acidity than administration at bedtime and hence is suggested for optimization of therapeutic efficacy." 01/01/1992 - "While it is well-established that ranitidine 150 mg/day is effective in preventing recurrence and complications of duodenal ulcer, the economic impact of maintenance therapy is unknown" Order ALL the reference details at left...
2.	Cimetidine (Biomet)FDA LinkGeneric 10/01/1982 - "Cimetidine therapy has proved to be effective in healing most duodenal ulcers and in reducing the frequency of reulceration" 10/01/1980 - "We studied the healing efficacy of cimetidine or placebo in 23 endoscopically proven duodenal ulcer outpatients in a randomized, controlled, prospective, double-blind trial" 12/01/1990 - "A randomized controlled trial was carried out to compare the efficacy of conventional 400 mg twice daily dose of cimetidine with single bedtime 800 mg dose, in 40 patients with endoscopically proven duodenal ulcer" 01/01/1982 - "An intensive antacid regimen, 15 to 30 ml 1 and 3 hours after each meal and at bedtime, has a significant effect on duodenal ulcer healing as compared to placebo and is as effective as cimetidine in endoscopically assessed trials" 04/01/1978 - "Clinical trials have shown cimetidine to be effective in healing duodenal ulcers and free of significant side effects with short-term usage" Order ALL the reference details at left...
3.	Omeprazole (Esomeprazole)FDA LinkGeneric 11/01/1992 - "It is concluded that omeprazole, even in the presence of adverse prognostic influences, results in significantly better healing of duodenal ulcer and relief from symptoms than H2-RA." 01/01/1994 - "As omeprazole is more effective than the H2-receptor antagonists in the acute treatment of duodenal ulcer, healing virtually all patients within 4 weeks (4), it may also be more effective in the maintenance treatment of duodenal ulcer disease" 01/01/1989 - "Open studies using maintenance treatment with low-dose omeprazole suggest that such therapy is effective in keeping refractory duodenal ulcer healed." 03/01/1996 - "BACKGROUND & AIMS: Omeprazole is less effective in healthy subjects than in patients with duodenal ulcers" 07/01/1991 - "Omeprazole is effective and safe in the treatment of gastric and duodenal ulcers." Order ALL the reference details at left...
4.	Sucralfate (Carafate)FDA LinkGeneric 06/09/1989 - "Analysis of procedurally correct cases demonstrated that sucralfate suspension was significantly more effective in healing duodenal ulcers than placebo at two, four, and eight weeks" 01/01/1987 - "The results indicate that sucralfate is significantly more effective than placebo in the prevention of recurrence of duodenal ulcer disease." 01/01/1991 - "Sucralfate is superior to placebo and comparable to H2 antagonists in the prevention of duodenal ulcer recurrence." 02/01/1989 - "However, sucralfate is superior to antacid in the ongoing maintenance therapy of chronic duodenal ulcer in childhood" 11/02/1992 - "It is concluded that 2 g sucralfate at bedtime is effective in preventing recurrence of duodenal ulcer symptoms." Order ALL the reference details at left...
5.	Misoprostol (Cytotec)FDA LinkGeneric 12/01/1996 - "The results of the randomized, double-blind, controlled trials show that misoprostol is the only antiulcer drug proven to be effective in the prevention of NSAID-induced gastric and duodenal ulcers as well as for reducing serious upper gastrointestinal complications (perforation and/or haemorrhage)" 11/11/1996 - "Misoprostol and H2 blockers were beneficial in the long-term prevention of duodenal ulcers; misoprostol or H2 blockers in the short-term prevention of duodenal ulcers remains to be confirmed." 11/01/1986 - "Irrespective of whether duodenal ulcer was healed or unhealed, significantly (p less than 0.01) more patients on misoprostol (50% at week 8) showed improvement (nil or mild as endpoint) than the placebo group" 07/27/1999 - "Previous studies have shown that misoprostol is effective in reducing the incidence of gastric and duodenal ulcers as well as serious gastrointestinal complications" 09/01/2000 - "CONCLUSION: Misoprostol, PPI, and double dose H2RA are effective in preventing chronic NSAID related endoscopic gastric and duodenal ulcers" Order ALL the reference details at left...
6.	lansoprazole (Prevacid)FDA LinkGeneric 08/10/1998 - "CONCLUSIONS: In patients with an active or a recent history of duodenal ulcer, lansoprazole-based triple therapy for 10 or 14 days is highly effective in the eradication of H pylori" 04/01/1998 - "CONCLUSIONS: In patients with active or a recent history of duodenal ulcer, a 14-day course of lansoprazole-based triple therapy without additional acid suppression therapy is highly effective in the eradication of H" 10/01/1996 - "CONCLUSIONS: Lansoprazole was effective for prompt symptom relief in most patients and was able to heal more than 90% of gastric and duodenal ulcers with minimal side effects." 10/01/1995 - "CONCLUSION: Lansoprazole is an effective and safe treatment for duodenal ulcer and the 15 mg dose is as effective as 30 or 60 mg." 09/01/1995 - "It is shown that lansoprazole is effective and safe for treatment of duodenal ulcer." Order ALL the reference details at left...
7.	Amoxicillin (Wymox)FDA LinkGeneric 01/01/2002 - "Eradication of Helicobacter pylori in patients with duodenal ulcer following the short course of treatment with azitromycin and amoxycillin]" 01/01/1999 - "A comparative study; one week treatment versus two weeks treatment with lansoprazol, amoxycillin and clarythromycin for the eradication of Helicobacter pylori in patient with gastric and duodenal ulcer]" 01/01/1998 - "METHODS: Eighty-one patients with duodenal ulcers were randomized to the following treatments: 39 cases with amoxycillin 1 g b.d" 07/01/1996 - "It was assumed that patients would derive no benefit from eradication therapy unless they had a duodenal ulcer, and that all OA patients received generic amoxicillin" 01/01/2007 - "The purpose of this research was to formulate and systematically evaluate in vitro and in vivo performances of mucoadhesive amoxicillin microspheres for the potential use of treating gastric and duodenal ulcers, which were associated with Helicobacter pylori" Order ALL the reference details at left...
8.	Famotidine (Pepcid)FDA LinkGeneric 01/01/1990 - "Famotidine, a novel H2 receptor antagonist appears to be effective and well tolerated in the treatment of most patients with duodenal ulcer." 08/01/1992 - "is superior to 40 mg famotidine nocte in duodenal ulcer healing." 01/01/1988 - "Multicenter studies examining the efficacy of famotidine in reducing the incidence of duodenal ulcer recurrence showed that famotidine was superior to placebo at all intervals examined" 03/01/1989 - "In conclusion: 1) famotidine appears to be an effective and safe therapy for duodenal ulcer treatment; 2) it seems to act not only by inhibiting gastric acid secretion but also influencing some parameters related to the gastric mucosal barrier." 01/01/1988 - "Famotidine appears to be an effective treatment for acute duodenal ulcer" Order ALL the reference details at left...
9.	GastrinsIBA 01/01/1993 - "pylori was eradicated in all patients who have received antibacterial therapy in 4 weeks, and serum gastrin concentrations were significantly decreased after eradication of the organism both in gastric and in duodenal ulcer diseases" 10/01/1977 - "Gastric acid and gastrin responses to AAM were found to be significantly greater in duodenal ulcer patients than in normal subjects" 07/01/1977 - "The duodenal ulcer patients showed an augmented and significantly greater release of GIP as well as of gastrin compared to normal subjects" 02/01/1986 - "Serum gastrin has been reported to increase after therapy with some agents effective in the treatment of duodenal ulcer (DU)" 01/01/1985 - "Dynamics of the basal gastrin concentration of duodenal ulcer patients during the development of remission of the disease]" Order ALL the reference details at left...
10.	Clarithromycin (Biaxin)FDA LinkGeneric 01/01/2006 - "When patients with non-susceptibility to clarithromycin were excluded, eradication rates were >80% for both gastric and duodenal ulcers in the two groups" 01/01/2002 - "Fromilide (clarithromycin) in eradication of Helicobacter pylori in patients with duodenal ulcer]" 01/01/2002 - "AIM: Comparison of two treatment regimens of eradication treatment of duodenal ulcer (DU) associated with Helicobacter pylori based on fromilid (clarithromycin)" 01/01/2002 - "Fromilid (clarithromycin) in eradication patients in patients with duodenal ulcer associated with Helicobacter pylori (comparison of two treatment variations)]" 06/01/1999 - "pylori in patients with duodenal ulcer, clarithromycin, 500 mg bid for 2 weeks, with RBC, 400 mg bid for 4 weeks, is equivalent to clarithromycin, 500 mg tid with RBC" Order ALL the reference details at left...

Therapies and Procedures

1.	Vagotomy 01/01/1986 - "It is concluded that the absence of mortality, the negligible postoperative morbidity, the clinical and functional results make high selective vagotomy the best treatment for uncomplicated duodenal ulcer." 08/01/1975 - "Vagotomy and pyloroplasty in most patients showing duodenal ulcer with reduced posthistamine secretion provide for good results." 01/01/1999 - "In 4 patients isolated laparoscopic radiofrequency vagotomy without gastric drainage in uncomplicated forms of duodenal ulcer was performed with good results." 01/01/1993 - "The author considers vagotomy to be insufficiently effective in the treatment of an uncomplicated duodenal ulcer" 05/01/1991 - "Preoperative intragastric pH measurement in the prognosis of the efficacy of vagotomy in duodenal ulcer]" Order ALL the reference details at left...
2.	Proximal Gastric Vagotomy 08/11/1977 - "Of the currently practiced procedures parietal cell vagotomy seems to offer the best results in duodenal ulcer patients although long-term follow-up examinations are not yet available." 04/01/1991 - "Although almost 20% of the reviewed patients continue to require regular or frequent medication, the study shows that highly selective vagotomy can be therapeutically effective for duodenal ulcer, particularly in preventing haemorrhage and perforation in patients who have previously suffered these complications" 11/01/2007 - "OBJECTIVE: To evaluate the long-term therapeutic efficacy of extended parietal cell vagotomy (EPCV) in the treatment of duodenal ulcer complicated with acute perforation" 06/01/1989 - "Proximal gastric vagotomy and intermittent and maintenance therapy with H2-antagonists have all been claimed to be effective in long-term management of duodenal ulcer disease" 01/01/1993 - "Evidence continues to accrue that proximal gastric vagotomy is a safe and effective elective operation for duodenal ulcer" Order ALL the reference details at left...
3.	Truncal Vagotomy 05/01/1999 - "CONCLUSIONS: Videoendoscopic truncal vagotomy seems to be an alternative treatment regimen for the management of chronic duodenal ulcer in a group of selected patients, as a simple, surgeon independent and efficient procedure" 11/01/1996 - "CONCLUSION: Truncal vagotomy by videothoracoscopy as a simple, surgeon independent and efficient procedure seems to be an alternative treatment regimen for the management of chronic duodenal ulcer in a group of selected patients" 12/01/1994 - "The efficacy of truncal vagotomy combined with pyloroplasty has been studied in 56 patients, divided into the following groups: Group I-29 patients submitted to bilateral truncal vagotomy (BTV) and pyloroplasty, as the method of treatment to solve the problem of perforated duodenal ulcer (initial and retrospective phase of study)" 08/01/1983 - "Randomized trial of truncal vagotomy with either pyloroplasty or pyloric dilatation in the surgical management of chronic duodenal ulcer." 07/01/1995 - "Thirty cases of uncomplicated duodenal ulcer treated by anterior superficial lesser curvature seromyotomy and posterior truncal vagotomy were studied to evaluate the efficacy of this procedure" Order ALL the reference details at left...
4.	Aftercare (After-Treatment) 01/01/1983 - "The best results were found in duodenal ulcers after treatment with Renitidin" 01/01/1986 - "A significant reduction was observed after treatment in patients with duodenal ulcer, both in the corpus and in the duodenal mucosa, whereas no difference was seen in the duodenum" 06/01/1968 - "Studies on the 24 hour urinary excretion of 5-hydroxyindoleacetic acid in patients with stomach or duodenal ulcer before, during and after treatment with Spasmophen in relation to the "basal HC1 excretion" and the clinical condition of patients]" 01/01/2001 - "Recurrence rate of duodenal ulcer (DU) within one and two years after treatment was studied in 42 DU patients with incomplete eradication of Helicobacter pylori (HP) and 16 DU patients with its complete eradication" 01/01/2000 - "pylori) eradication on the natural history of duodenal ulcer disease and the reinfection rate after treatment in a developing country" Order ALL the reference details at left...
5.	Gastrectomy 01/01/1973 - "Curling's ulcer in a child: report of a case cured by gastrectomy and review of the literature]" 03/01/1963 - "This paper reports a study of the enzyme activity of the gastric mucosa obtained by oral biopsy from normal patients and from those with either gastric or duodenal ulcers or from post-gastrectomy patients" 10/01/2006 - "The first case, a man aged 36 years, was a classical one, with a G(jejuno)CF appearing three years after a gastrectomy with Reichel-Polya reconstruction for duodenal ulcer, resolved by a "revision gastrectomy" en block with segmental resection of the jejunum and transverse colon" 11/01/2004 - "Patient 2 was a 48-year-old man who had a polya gastrectomy for a large perforated duodenal ulcer" 02/01/2004 - "He had undergone subtotal gastrectomy due to duodenal ulcer at age 19" Order ALL the reference details at left...

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