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Non-Steroidal Anti-Inflammatory Agents (NSAIDs)

5342  relevant articles (469 outcomes, 841 trials/studies) found for this Bio-Agent

Description: Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)

Also Known As:
NSAIDs; Anti-Inflammatory Agents, Non-Steroidal; Anti Inflammatory Agents, Nonsteroidal; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Antirheumatic Agents, Non-Steroidal; Nonsteroidal Anti-Inflammatory Agents; Agents, Aspirin-Like; Agents, Non-Steroidal Anti-Inflammatory; Agents, Non-Steroidal Anti-Rheumatic; Agents, Non-Steroidal Antirheumatic; Agents, Nonsteroidal Anti-Inflammatory; Agents, Nonsteroidal Antiinflammatory; Analgesics, Anti Inflammatory; Anti Inflammatory Agents, Non Steroidal; Anti Rheumatic Agents, Non Steroidal; Anti-Inflammatory Agents, Nonsteroidal; Anti-Inflammatory Analgesics; Antirheumatic Agents, Non Steroidal; Aspirin Like Agents; Non Steroidal Anti Inflammatory Agents; Non-Steroidal Anti-Rheumatic Agents; Non-Steroidal Antirheumatic Agents; Nonsteroidal Anti Inflammatory Agents; Nonsteroidal Antiinflammatory Agents; Analgesics, Anti-Inflammatory; Anti-Rheumatic Agents, Non-Steroidal; Aspirin-Like Agents

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rigas, Basil: 7 articles (09/2008 - 01/2002)
2. Williams, Jennie L: 3 articles (09/2008 - 05/2002)
3. White, William B: 3 articles (12/2007 - 07/2004)
4. Tarnawski, Andrzej S: 3 articles (06/2007 - 02/2002)
5. Moore, Nicholas: 3 articles (07/2006 - 01/2003)
6. McLaughlin, Joseph K: 3 articles (12/2005 - 02/2002)
7. Olsen, Jørgen H: 3 articles (12/2005 - 02/2002)
8. Friis, Søren: 3 articles (12/2005 - 03/2003)
9. Sørensen, Henrik Toft: 3 articles (12/2005 - 02/2002)
10. Ouyang, Qin: 3 articles (10/2004 - 03/2002)

Related Diseases

1. Pain (Aches)
2. Osteoarthritis
3. Inflammation
4. Rheumatoid Arthritis
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Aspirin (Acetylsalicylic Acid)
2. Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
3. Acetaminophen (Paracetamol)
4. Analgesics (Analgesic Drugs)
5. Opioid Analgesics (Opioids)
6. celecoxib (Celebrex)
7. Misoprostol (Cytotec)
8. Omeprazole (Esomeprazole)
9. Ibuprofen (Motrin)
10. Cyclooxygenase 2 (Cyclooxygenase-2)

Related Therapies and Procedures

1. Chemoprevention
2. Analgesia
3. Oral Surgery (Maxillofacial Surgery)
4. Oral Surgical Procedures
5. Thoracotomy

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