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Baclofen

A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Also Known As:
Apo-Baclofen; Atrofen; Ba-34,647; Ba-34647; Baclofen AWD; Baclofène-Irex; Baclospas; CIBA-34,647-BA; Clofen; Gen-Baclofen; Genpharm; Lebic; Lioresal; Liorésal; Nu-Baclo; PCP-GABA; PMS-Baclofen; beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid; beta-(p-Chlorophenyl)-gamma-aminobutyric Acid; AWD, Baclofen; Apo Baclofen; ApoBaclofen; Ba34,647; Ba34647; Baclofène Irex; BaclofèneIrex; CIBA34,647BA; GABA, Chlorophenyl; Gen Baclofen; GenBaclofen; Nu Baclo; NuBaclo; PMS Baclofen; PMSBaclofen; Baclophen; Chlorophenyl GABA; Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
Networked: 2556 relevant articles (362 outcomes, 367 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Rolland, Benjamin: 32 articles (02/2020 - 11/2010)
2. Bordet, Régis: 22 articles (12/2019 - 11/2010)
3. Cottencin, Olivier: 22 articles (05/2019 - 11/2010)
4. Leggio, Lorenzo: 21 articles (12/2021 - 09/2003)
5. Addolorato, Giovanni: 19 articles (01/2020 - 09/2003)
6. Deheul, Sylvie: 18 articles (05/2019 - 11/2010)
7. Haber, Paul S: 15 articles (01/2022 - 12/2007)
8. Gautier, Sophie: 14 articles (12/2019 - 03/2014)
9. Morley, Kirsten C: 13 articles (01/2022 - 01/2018)
10. Auffret, Marine: 13 articles (12/2019 - 05/2014)

Related Diseases

1. Dystonia (Limb Dystonia)
2. Alcoholism (Alcohol Abuse)
3. Pain (Aches)
4. Spasm (Spasms)
5. Cerebral Palsy (Spastic Diplegia)

Related Drugs and Biologics

1. gamma-Aminobutyric Acid (GABA)
2. GABA-B Receptor Agonists
3. Gabapentin (Neurontin)
4. tizanidine (Zanaflex)
5. Morphine (MS Contin)
6. Carbamazepine (Tegretol)
7. GABA Agonists (GABA Receptor Agonists)
8. Clonidine (ST 155)
9. Diazepam (Valium)
10. Topiramate (Topamax)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Injections
4. Catheters
5. Transcutaneous Electric Nerve Stimulation (TENS)