Prilocaine Drug Combination Lidocaine

A topical local anesthetic preparation that is composed of a mixture of lidocaine and prilocaine. It is used to provide anesthesia during minor surgery and for the treatment of PREMATURE EJACULATION.

Also Known As:

Lidocaine, Prilocaine Drug Combination; EMLA Cream; Eutectic Lidocaine-Prilocaine; Eutectic Mixture of Local Anesthetics; Fortacin; Lidocaine Prilocaine; Lidocaine-Prilocaine Drug Combination; Oraqix; PSD 502; PSD-502; PSD502; Topical Eutectic-Like Mixture for Premature Ejaculation; Eutectic Lidocaine Prilocaine; Lidocaine Prilocaine Drug Combination; Lidocaine-Prilocaine, Eutectic; Prilocaine, Lidocaine; Topical Eutectic Like Mixture for Premature Ejaculation

Networked: 506 relevant articles (117 outcomes, 139 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Andersson, Lars: 6 articles (06/2021 - 01/2005)
2.	Abbas, Ahmed M: 5 articles (05/2020 - 03/2017)
3.	Montorsi, Francesco: 3 articles (04/2022 - 12/2005)
4.	Salonia, Andrea: 3 articles (04/2022 - 05/2008)
5.	Ohlsson, Arne: 3 articles (01/2020 - 06/2015)
6.	Shah, Prakeshkumar S: 3 articles (01/2020 - 06/2015)
7.	Cracowski, Jean-Luc: 3 articles (01/2013 - 03/2007)
8.	Khamis, Yasser: 2 articles (02/2022 - 03/2020)
9.	Mahmoud, Mostafa: 2 articles (02/2022 - 01/2019)
10.	Taher, Ayman: 2 articles (02/2022 - 01/2019)

Related Diseases

1.	Pain (Aches) 01/01/2019 - "Lidocaine-prilocaine cream is the most effective medication that can be used for IUD insertion-related pain. " 01/01/2015 - "Lidocaine-prilocaine cream proved the most effective in pain control regardless of the origin of pain. " 02/01/2011 - "Although most patients experienced limited pain during scaling, a significant reduction of pain is achieved by using EMLA cream and ultrasonic scaler." 01/01/2022 - "In a previous trial, we showed that the combination of Eutectic Mixture of Local Anesthetics (EMLA) + Sucrose + Ring Block (RB) was significantly effective in reducing pain during circumcision. " 06/29/2022 - "There was a significant reduction in pain scores during intravenous cannulation in the CoolSense group compared to the EMLA cream group (mean pain score 7.14 ± 4.322 versus 29.32 ± 8.95, p value 0.001). "
2.	Shock 01/01/2018 - "To identify the enhancing effect of extracorporeal shock wave-mediated transdermal drug delivery, 24 Wistar rats were randomly assigned to four groups: (i) topical application of a eutectic mixture of local anesthetics (EMLA); (ii) 1-MHz ultrasound; (iii) ESWT pre-treatment combined with EMLA application; (iv) ESWT concurrent with EMLA application on rat tails. " 07/01/1996 - "EMLA cream (10 g) was applied on the skin over the area (64-100 cm2) where the shock waves were to be focussed. " 10/01/1996 - "This randomized, double blind, placebo controlled study evaluated the efficacy of EMLA cream during extracorporeal shock wave lithotripsy (ESWL) using the Dornier MFL 5000 lithotripter. " 07/01/1996 - "EMLA cream for renal extracorporeal shock wave lithotripsy in ambulatory patients." 01/01/1993 - "A comparative randomized double-blind study between 99 patients with (group 1) and 100 without (group 2) cutaneous anesthesia with a lidocaine-prilocaine cream during extracorporeal shock wave lithotripsy (ESWL*) with an unmodified Dornier HM3 lithotriptor was done. "
3.	Premature Ejaculation 02/01/2006 - "The use of topical EMLA-cream-only seems to be an effective treatment of premature ejaculation." 12/01/2002 - "Therefore, lidocaine-prilocaine cream 5% is effective in premature ejaculation and 20 min of application time before sexual contact is the optimum period." 10/01/1995 - "We evaluated the efficacy of a new lidocaine-prilocaine cream in preventing premature ejaculation. " 09/01/2010 - "Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study." 11/01/1996 - "Re: Efficacy of prilocaine-lidocaine cream in the treatment of premature ejaculation."
4.	Wounds and Injuries (Trauma) 01/01/2015 - "In the pretreatment group, EMLA cream was applied during wound inspection. " 09/01/2001 - "It was concluded that lidocaine/prilocaine cream as topical anaesthetic agent had no adverse effect in an incisional wound model, furthermore it may have some beneficial effects on wound healing which remains to be evaluated and it can be used safely in day-to-day emergency practices." 07/01/1991 - "As a result of these investigations, we do not recommend the use of EMLA cream in wounds." 07/01/1991 - "This investigation evaluated the potential toxicity of EMLA cream in wounds by measuring its effect on host defenses and on the biology of wound repair. " 09/01/2003 - "Sharp wound debridement in local anaesthesia using EMLA cream: 6 years' experience in 1084 patients."
5.	Neoplasms (Cancer) 11/01/2018 - "The present results review that the application of EMLA cream for 30 min is suitable, acceptable, and convenient in cancer patients with totally implantable venous access device undergoing needle insertion." 09/01/1997 - "Differences among raters evaluating the success of EMLA cream in alleviating procedure-related pain in children with cancer." 07/01/1996 - "Resolution of tumor pain with EMLA cream." 01/01/1995 - "Resolution of tumor pain with EMLA cream: a case report." 09/01/1997 - "We evaluated the analgesic efficacy of EMLA cream after repeated bone marrow aspirations or lumbar punctures (LPs) in children with cancer, and compared the ratings among patients, their parents, physicians, and nurses. "

Related Drugs and Biologics

1.	Prilocaine Drug Combination Lidocaine
2.	Lidocaine (Xylocaine)
3.	Anesthetics (Anesthetic Agents)
4.	Analgesics (Analgesic Drugs)
5.	Local Anesthetics
6.	Prilocaine (Citanest)
7.	Tetracaine (Amethocaine)
8.	Solutions
9.	Botulinum Toxins (Botulinum Toxin)
10.	Diclofenac (SR 38)

Related Therapies and Procedures

1.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
2.	Anesthesia
3.	Lasers (Laser)
4.	Analgesia
5.	Debridement