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N- ((3,4- dihydro- 3- hydroxy- 2- methyl- 2- (4'- methyl- 3'- pentenyl)- 2H- 1- benzopyran- 6- yl)carbonyl)threonine

an antifibrotic agent isolated from Streptomycesn xiamenensis; structure in first source

Also Known As:

xiamenmycin; xiamenmycin A

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - N-((3,4-dihydro-3-hydroxy-2-methyl-2-(4'-methyl-3'-pentenyl)-2H-1-benzopyran-6-yl)carbonyl)threonine: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - N-((3,4-dihydro-3-hydroxy-2-methyl-2-(4'-methyl-3'-pentenyl)-2H-1-benzopyran-6-yl)carbonyl)threonine: 1
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Threonine: 2168
      - N-((3,4-dihydro-3-hydroxy-2-methyl-2-(4'-methyl-3'-pentenyl)-2H-1-benzopyran-6-yl)carbonyl)threonine: 1
  - Neutral Amino Acids: 200
    - Threonine: 2168
      - N-((3,4-dihydro-3-hydroxy-2-methyl-2-(4'-methyl-3'-pentenyl)-2H-1-benzopyran-6-yl)carbonyl)threonine: 1

Experts

1.	Fan, Si-Teng: 1 article (05/2013)
2.	Li, Jun: 1 article (05/2013)
3.	Liu, Xiao-Jin: 1 article (05/2013)
4.	Wang, Ya-Hui: 1 article (05/2013)
5.	Wu, Zheng: 1 article (05/2013)
6.	Xu, Jun: 1 article (05/2013)
7.	Xu, Min-Juan: 1 article (05/2013)
8.	Yang, Xiao-Mei: 1 article (05/2013)
9.	Zhang, Zhi-Gang: 1 article (05/2013)

Related Diseases

1.	Hypertrophic Cicatrix (Hypertrophic Scar) 05/01/2013 - "Taken together, the compound could simultaneously suppress both the inflammatory and mechanical stress responses, which are the two pivotal pathological processes in hypertrophic scar formation, thus suggesting that xiamenmycin can serve as a potential agent for treating hypertrophic scar formation and other excessive fibrotic diseases." 05/01/2013 - "Xiamenmycin attenuates hypertrophic scars by suppressing local inflammation and the effects of mechanical stress." 05/01/2013 - "Here we found that a benzopyran natural product, xiamenmycin, could significantly attenuate hypertrophic scar formation in a mechanical stretch-induced mouse model. "
2.	Pathologic Processes 05/01/2013 - "Taken together, the compound could simultaneously suppress both the inflammatory and mechanical stress responses, which are the two pivotal pathological processes in hypertrophic scar formation, thus suggesting that xiamenmycin can serve as a potential agent for treating hypertrophic scar formation and other excessive fibrotic diseases."
3.	Inflammation (Inflammations) 05/01/2013 - "Xiamenmycin attenuates hypertrophic scars by suppressing local inflammation and the effects of mechanical stress."

Related Drugs and Biologics

1.	Benzopyrans