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Threonine (L-Threonine)

An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Also Known As:
L-Threonine; L Threonine
Networked: 2168 relevant articles (35 outcomes, 163 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Blennow, Kaj: 17 articles (10/2022 - 08/2002)
2. Engelborghs, Sebastiaan: 12 articles (11/2022 - 03/2006)
3. Zetterberg, Henrik: 12 articles (10/2022 - 01/2010)
4. Hampel, Harald: 11 articles (10/2012 - 08/2002)
5. Scheltens, Philip: 9 articles (01/2022 - 01/2010)
6. Chen, Xiang: 7 articles (10/2020 - 03/2006)
7. Martin, Jean-Jacques: 7 articles (10/2016 - 09/2007)
8. Trojanowski, John Q: 7 articles (02/2015 - 04/2009)
9. Buerger, Katharina: 7 articles (10/2007 - 08/2002)
10. Teunissen, Charlotte E: 6 articles (11/2022 - 10/2012)

Related Diseases

1. Neoplasms (Cancer)
08/01/2005 - "Although the mechanism of action of Apoptin is presently unknown, it seems to function by the induction of programmed cell death (PCD) after translocation from the cytoplasm to the nucleus and arresting the cell cycle at G2/M, possibly by interfering with the cyclosome.(2) In addition, cancer specific phosphorylation of Threonine residue 108 has been suggested to be important for Apoptin's function to kill tumor cells.(3) In contrast to the large number of publications reporting that nuclear localization, induction of PCD and phosphorylation of Apoptin is restricted to cancer cells, several recent studies have shown that Apoptin has the ability to migrate to the nucleus and induce PCD in some of the normal cell lines tested. "
03/25/2023 - "Finally, we demonstrate that PP6c opposes the activation of large tumor suppressor 1 (LATS1) by dephosphorylating Threonine 35 (T35) on Mps One Binder (MOB1), thereby blocking the interaction of MOB1 and LATS1. "
01/01/2023 - "Finally, we demonstrate that PP6c opposes the activation of large tumor suppressor 1 (LATS1) by dephosphorylating Threonine 35 (T35) on Mps One Binder (MOB1), thereby blocking the interaction of MOB1 and LATS1. "
11/01/2022 - "PKG II secreted via the classical endoplasmic reticulum-Golgi apparatus secretory pathway blocks the activation of EGFR through phosporalting its threonine 406 and has an anti-tumor effect."
01/28/2022 - "Fbw7 binds to a phosphorylated Myc degron centered at threonine 58 (T58), and mutations of Fbw7 or T58 impair Myc degradation in cancers. "
2. Weight Gain
3. Body Weight (Weight, Body)
4. Obesity
5. Fibrosis (Cirrhosis)

Related Drugs and Biologics

1. Serine (L-Serine)
2. Methionine (L-Methionine)
3. Amino Acids
4. Proteins (Proteins, Gene)
5. Glycine (Aminoacetic Acid)
6. Lysine (L-Lysine)
7. Arginine (L-Arginine)
8. Caseins (Casein)
9. Glutamic Acid (Glutamate)
10. Phosphoprotein Phosphatases (Phosphatases, Protein)

Related Therapies and Procedures

1. Therapeutics
2. Oral Hygiene (Dental Hygiene)
3. Total Parenteral Nutrition
4. Drug Therapy (Chemotherapy)
5. Castration