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human MIRN424 microrna

RefSeq NR_029946

Also Known As:

MIRN424 microrna, human; MIR322, human; MIRN322, human; Mir-322, human; hsa-mir-424; miR-424, human; miR424, human; microRNA-424, human

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Untranslated RNA: 2850
      - Small Untranslated RNA: 566
        MicroRNAs: 67298
        human MIRN424 microrna: 3
    - Antisense RNA: 1599
      - MicroRNAs: 67298
        human MIRN424 microrna: 3
- Antisense Elements (Genetics): 31
  - Antisense RNA: 1599
    - MicroRNAs: 67298
      - human MIRN424 microrna: 3

Experts

1.	Chu, Ping: 1 article (01/2022)
2.	Li, Fengling: 1 article (01/2022)
3.	Li, Pan: 1 article (01/2022)
4.	Song, Yuchun: 1 article (01/2022)
5.	Barth, Stephanie: 1 article (03/2011)
6.	Faggioni, Alberto: 1 article (03/2011)
7.	Grässer, Friedrich A: 1 article (03/2011)
8.	Imig, Jochen: 1 article (03/2011)
9.	Meister, Gunter: 1 article (03/2011)
10.	Motsch, Natalie: 1 article (03/2011)

Related Diseases

1.	Epstein-Barr Virus Infections 03/01/2011 - "Here, we report a comprehensive miRNA-profiling study and show that hsa-miR-424, -223, -199a-3p, -199a-5p, -27b, -378, -26b, -23a, -23b were upregulated and hsa-miR-155, -20b, -221, -151-3p, -222, -29b/c, -106a were downregulated more than 2-fold due to EBV-infection of DLBCL. "
2.	Endometrial Neoplasms (Endometrial Cancer) 01/01/2022 - "1119 differential mRNAs, 14 differential lncRNAs, and 65 differential miRNAs were screened in TCGA; we constructed a ceRNA regulatory network composed of 5 DELs, 7 DEMs, and 90 DEGs; String combined with Cytoscape to screen out Top10 hub genes, namely: LEFTY1, LIN28A, LHX3, ST8SIA3, CEP55, FBXO32, DCN, ANGPTL1, ADRA1A, and KCNMA1; the StarBase database verification results show that ADRA1A, ANGPTL1, FBXO32, KCNMA1, and DCN are downregulated in endometrial cancer tissues; LEFTY1, LIN28A, LHX3, ST8SIA3, and CEP55 are upregulated in endometrial cancer; the constructed lncRNA-miRNA-hub Top10 mRNA network map identified CTD-2314B22, RP11-89 K21/hsa-miR-143, hsa-miR-424/LEFTY1, LIN28A, LHX3, ST8SIA3, and CEP55 signal axis; survival analysis results show that CTD-2314B22, RP11-89 K21, hsa-miR-96, hsa-miR-211, LHX3, ST8SIA3, and DCN are all related to survival; RT-qPCR results indicate CTD-2314B22, RP11-89 K21, LEFTY1, LIN28A, LHX3, ST8SIA3, and CEP55 are upregulated in endometrial cancer cells, and hsa-miR-143 and hsa-miR-424 are downregulated in endometrial cancer cells. "
3.	Breast Neoplasms (Breast Cancer) 11/05/2022 - "Additionally, knockdown of transcription factor YY1 and transfection of hsa-miR-424 mimics had a synergistic effect in reducing hypoxia-induced VWF production of breast cancer cells, cell migration and angiogenesis in vitro." 11/05/2022 - "Hypoxia promotes the expression of Von Willebrand factor in breast cancer cells by up-regulating the transcription factor YY1 and down-regulating the hsa-miR-424."
4.	Hypoxia (Hypoxemia) 11/05/2022 - "Here, we proved that hypoxia up-regulated the transcription factor YY1 and down-regulated hsa-miR-424 to increase the expression level of VWF. " 11/05/2022 - "Additionally, knockdown of transcription factor YY1 and transfection of hsa-miR-424 mimics had a synergistic effect in reducing hypoxia-induced VWF production of breast cancer cells, cell migration and angiogenesis in vitro." 11/05/2022 - "Hypoxia promotes the expression of Von Willebrand factor in breast cancer cells by up-regulating the transcription factor YY1 and down-regulating the hsa-miR-424."

Related Drugs and Biologics

1.	MicroRNAs (MicroRNA)
2.	Long Noncoding RNA
3.	YY1 Transcription Factor
4.	von Willebrand Factor
5.	Messenger RNA (mRNA)
6.	Competitive Endogenous RNA
7.	human MIRN211 microRNA
8.	human MIRN143 microRNA